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Segment Information (Tables) | 6 Months Ended
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Jun. 30, 2026
Segment Reporting [Abstract] |
Schedule of Reconciliation of Segment Loss Before Income Taxes and Total Consolidated Loss Before Income Taxes | The following table presents selected financial information with respect to the Company’s single operating segment for the three and six months ended June 30, 2026 and 2025 (in thousands):
| Therapeutics Segment
| Three Months Ended June 30, |  | Six Months Ended June 30, |
| 2026 |  | 2025 |  | 2026 |  | 2025 |
Product revenue, net | $ | 3,604 |  |  | $ | — |  |  | $ | 3,604 |  |  | $ | — |  |
Less: |  |  |  |  |  |  |  |
Cost of goods sold | 93 |  |  | — |  |  | 93 |  |  | — |  |
External research and development expenses - TV programs, including cost sharing | 40,419 |  |  | 37,594 |  |  | 78,883 |  |  | 84,052 |  |
Other research and development expenses, including small molecule programs | 16,494 |  |  | 24,847 |  |  | 40,048 |  |  | 54,347 |  |
Personnel related research and development expenses | 40,106 |  |  | 40,255 |  |  | 81,934 |  |  | 80,524 |  |
Total research and development expenses | 97,019 |  |  | 102,696 |  |  | 200,865 |  |  | 218,923 |  |
Personnel related selling, general and administrative expenses | 22,921 |  |  | 20,115 |  |  | 45,485 |  |  | 38,853 |  |
Other selling, general and administrative expenses | 13,362 |  |  | 12,152 |  |  | 24,309 |  |  | 22,767 |  |
Total selling, general and administrative expenses | 36,283 |  |  | 32,267 |  |  | 69,794 |  |  | 61,620 |  |
Intangible asset amortization | $ | 750 |  |  | $ | — |  |  | $ | 750 |  |  | $ | — |  |
Segment operating expenses | 134,145 |  |  | 134,963 |  |  | 271,502 |  |  | 280,543 |  |
Segment loss from operations | (130,541) |  |  | (134,963) |  |  | (267,898) |  |  | (280,543) |  |
Segment interest and other income, net | 2,988 |  |  | 10,844 |  |  | 11,898 |  |  | 23,454 |  |
Segment net loss | $ | (127,553) |  |  | $ | (124,119) |  |  | $ | (256,000) |  |  | $ | (257,089) |  |

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- Definition Tabular disclosure of segment reporting. Includes, but is not limited to, reconciliation of reportable segment amount to corresponding consolidated total. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 31 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-31 Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 34 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-34 Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 32 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-32 Reference 4: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 Reference 5: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 26C -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-26C Reference 6: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 26B -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-26B Reference 7: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 26A -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-26A Reference 8: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 9: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 10: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 15 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-15 + Details
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