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Commitments and Contingencies | 6 Months Ended
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Jun. 30, 2026
Commitments and Contingencies Disclosure [Abstract] |
Commitments and Contingencies | Commitments and Contingencies Lease Obligations In May 2018, the Company entered into an operating lease for its corporate headquarters in South San Francisco (the "Headquarters Lease"), and in April 2023, the Company entered into a finance lease for its clinical manufacturing site in Salt Lake City (the "SLC Lease"). Both leases are further described in Note 7, "Commitments and Contingencies," to the consolidated financial statements in the Company's 2025 Annual Report on Form 10-K. There were no changes to the terms of the leases recognized under ASC 842 during the three and six months ended June 30, 2026 or 2025. The following table summarizes lease costs recognized for the periods presented (in thousands):
| Three Months Ended June 30, |  | Six Months Ended June 30,
| 2026 |  | 2025 |  | 2026 |  | 2025
Operating lease cost | $ | 1,821 |  |  | $ | 1,893 |  |  | $ | 3,674 |  |  | $ | 3,786 |
Finance lease cost: |  |  |  |  |  |  |
Amortization of ROU assets | 915 |  |  | 911 |  |  | 1,831 |  |  | 1,798 |
Interest | 178 |  |  | 180 |  |  | 357 |  |  | 361 |
Variable lease cost | 1,792 |  |  | 1,338 |  |  | 2,832 |  |  | 2,691 |
Total lease costs | $ | 4,706 |  |  | $ | 4,322 |  |  | $ | 8,694 |  |  | $ | 8,636 |
Operating cash flows for operating leases were $3.0 million and $2.9 million for the three months ended June 30, 2026 and 2025, respectively, and $6.0 million and $5.8 million for the six months ended June 30, 2026 and 2025, respectively. Indemnification In the ordinary course of business, the Company may provide indemnifications of varying scope and terms to vendors, lessors, business partners, board members, officers, and other parties with respect to certain matters, including, but not limited to, losses arising out of breach of such agreements, services to be provided by the Company, negligence or willful misconduct of the Company, violations of law by the Company, or from intellectual property infringement claims made by third parties. In addition, the Company has entered into indemnification agreements with directors and certain officers and employees that will require the Company, among other things, to indemnify them against certain liabilities that may arise by reason of their status or service as directors, officers or employees. No demands have been made upon the Company to provide indemnification under such agreements, and thus, there are no claims that the Company is aware of that could have a material effect on the Company’s Condensed Consolidated Balance Sheets, Condensed Consolidated Statements of Operations and Comprehensive Loss, or Condensed Consolidated Statements of Cash Flows. Commitments In the normal course of business, the Company enters into firm purchase commitments primarily related to supply of commercial product, certain research and development services, and clinical manufacturing activities. The Company had contractual obligations of $104.7 million as of June 30, 2026, of which $91.9 million related to supply of commercial product, and $44.3 million as of December 31, 2025. Contingencies From time to time, the Company may be involved in lawsuits, arbitration, claims, investigations and proceedings consisting of intellectual property, employment and other matters which arise in the ordinary course of business. The Company records accruals for loss contingencies to the extent that the Company concludes that it is probable that a liability has been incurred and the amount of the related loss can be reasonably estimated.

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