<SEC-DOCUMENT>0001714899-26-000056-index.html : 20260421
<SEC-HEADER>0001714899-26-000056.hdr.sgml : 20260421
<ACCEPTANCE-DATETIME>20260421163415
ACCESSION NUMBER:		0001714899-26-000056
CONFORMED SUBMISSION TYPE:	DEFA14A
PUBLIC DOCUMENT COUNT:		3
FILED AS OF DATE:		20260421
DATE AS OF CHANGE:		20260421

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Denali Therapeutics Inc.
		CENTRAL INDEX KEY:			0001714899
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				463872213
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEFA14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38311
		FILM NUMBER:		26880003

	BUSINESS ADDRESS:	
		STREET 1:		161 OYSTER POINT BLVD.
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
		BUSINESS PHONE:		(650) 866-8547

	MAIL ADDRESS:	
		STREET 1:		161 OYSTER POINT BLVD.
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEFA14A
<SEQUENCE>1
<FILENAME>a2026fy25defa14aproxy-defi.htm
<DESCRIPTION>DEFA14A ADDITIONAL MATERIALS
<TEXT>
Document 1 - file: a2026fy25defa14aproxy-defi.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>denalitherapeuticsinc_vxna.jpg
<TEXT>
Document 2 - file: denalitherapeuticsinc_vxna.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>denalitherapeuticsinc_vxnaa.jpg
<TEXT>
Document 3 - file: denalitherapeuticsinc_vxnaa.jpg

</DOCUMENT>
</SEC-DOCUMENT>