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SEGMENT INFORMATION (Tables) | 9 Months Ended
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Sep. 30, 2025
Segment Reporting [Abstract] |
Schedule of reconciliation to the consolidated net loss | A reconciliation to the consolidated net loss for the three and nine months ended September 30, 2025 and September 30, 2024 is included in the table below:
| Three Months Ended |  | Nine Months Ended
(in thousands) | September 30, 2025 |  | September 30, 2024 |  | September 30, 2025 |  | September 30, 2024
Revenue: |  |  |  |  |  |  |
Screening revenue | $ | 32,807 |  |  | $ | 25,374 |  |  | $ | 96,319 |  |  | $ | 77,076 |
Development services revenue | 3,387 |  |  | 3,278 |  |  | 7,256 |  |  | 10,267 |
Total revenue | 36,194 |  |  | 28,652 |  |  | 103,575 |  |  | 87,343 |
Costs and operating expenses: |  |  |  |  |  |  |
Cost of screening revenue (exclusive of amortization of intangible assets) (1)(2) | 15,910 |  |  | 15,970 |  |  | 52,379 |  |  | 45,481 |
Cost of development services revenue (1)(2) | 544 |  |  | 1,442 |  |  | 2,216 |  |  | 3,499 |
Compensation | 53,375 |  |  | 84,733 |  |  | 173,537 |  |  | 257,578 |
Depreciation and intangible assets amortization expense | 37,646 |  |  | 38,630 |  |  | 112,577 |  |  | 114,808 |
Stock-based compensation | 13,868 |  |  | 16,871 |  |  | 43,068 |  |  | 70,980 |
Professional services | 8,831 |  |  | 11,298 |  |  | 27,353 |  |  | 52,459 |
Cloud computing and information technology | 6,416 |  |  | 7,517 |  |  | 19,537 |  |  | 23,619 |
Clinical studies | 7,835 |  |  | 8,048 |  |  | 20,020 |  |  | 39,280 |
Laboratory supplies and research collaborations | 3,242 |  |  | 8,556 |  |  | 10,421 |  |  | 37,631 |
Facilities | 5,517 |  |  | 6,185 |  |  | 16,510 |  |  | 21,344 |
Other segment expenses (3) | 8,301 |  |  | 12,909 |  |  | 35,709 |  |  | 51,948 |
Goodwill and intangible assets impairment | — |  |  | — |  |  | 28,000 |  |  | 1,420,936 |
Total costs and operating expenses | 161,485 |  |  | 212,159 |  |  | 541,327 |  |  | 2,139,563 |
Loss from Operations | (125,291) |  |  | (183,507) |  |  | (437,752) |  |  | (2,052,220) |
Other income (expense): |  |  |  |  |  |  |
Interest income | 6,107 |  |  | 11,661 |  |  | 20,695 |  |  | 17,367 |
Other income (expense), net | 466 |  |  | (561) |  |  | (929) |  |  | (514) |
Benefit from income taxes | 29,741 |  |  | 46,719 |  |  | 108,811 |  |  | 105,428 |
Net Loss | $ | (88,977) |  |  | $ | (125,688) |  |  | $ | (309,175) |  |  | $ | (1,929,939) |
(1) Cost of screening revenue (exclusive of amortization of intangible assets) and cost of development services revenue include stock-based compensation expense. See Note 8 — Stock-Based Compensation for further details. (2) Cost of screening revenue (exclusive of amortization of intangible assets) and cost of development services revenue include $1.3 million and $4.9 million of depreciation expense for the three and nine months ended September 30, 2025 and $0.6 million and $3.8 million for the three and nine months ended September 30, 2024. (3) Other segment expenses primarily includes costs related to contractors and temporary labor, marketing expenses, legal expenses, and credit loss expense

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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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