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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Revenue:        
Total revenue $ 36,194 $ 28,652 $ 103,575 $ 87,343
Costs and operating expenses:        
Cost of revenue — amortization of intangible assets 33,473 33,473 100,417 100,417
Research and development [1] 48,647 78,231 148,898 274,052
Sales and marketing 25,503 35,625 89,021 123,433
General and administrative [2] 37,408 47,418 120,396 171,745
Goodwill and intangible assets impairment 0 0 28,000 1,420,936
Total costs and operating expenses 161,485 212,159 541,327 2,139,563
Loss from operations (125,291) (183,507) (437,752) (2,052,220)
Other income:        
Interest income 6,107 11,661 20,695 17,367
Other income (expense), net 466 (561) (929) (514)
Total other income, net 6,573 11,100 19,766 16,853
Loss before income taxes (118,718) (172,407) (417,986) (2,035,367)
Benefit from income taxes 29,741 46,719 108,811 105,428
Net loss $ (88,977) $ (125,688) $ (309,175) $ (1,929,939)
Net loss        
Net loss per share—basic (in dollars per share) $ (2.46) $ (3.94) $ (8.73) $ (61.61)
Net loss per share—diluted (in dollars per share) $ (2.46) $ (3.94) $ (8.73) $ (61.61)
Weighted-average shares of common stock used in computing net loss per share—basic (in shares) 36,124,256 31,880,054 35,415,266 31,326,117
Weighted-average shares of common stock used in computing net loss per share—diluted (in shares) 36,124,256 31,880,054 35,415,266 31,326,117
Screening revenue        
Revenue:        
Total revenue [3] $ 32,807 $ 25,374 $ 96,319 $ 77,076
Costs and operating expenses:        
Cost of revenue [4] 15,910 15,970 52,379 45,481
Development services revenue        
Revenue:        
Total revenue 3,387 3,278 7,256 10,267
Costs and operating expenses:        
Cost of revenue [5] $ 544 $ 1,442 $ 2,216 $ 3,499
[1] Includes related party research and development expenses of $973 and $2,947 for the three and nine months ended September 30, 2025 and $6,588 and $16,700 for the three and nine months ended September 30, 2024, respectively.
[2] Includes related party general and administrative expenses of nil for the three and nine months ended September 30, 2025 and $1 and $104 for the three and nine months ended September 30, 2024, respectively.
[3] ncludes related party screening revenue of $50 and $179 for the three and nine months ended September 30, 2025 and $129 and $366 for the three and nine months ended September 30, 2024, respectively.
[4] ncludes related party cost of screening revenue of $1,237 and $3,924 for the three and nine months ended September 30, 2025 and $3,658 and $9,784 for the three and nine months ended September 30, 2024, respectively.
[5] Includes related party cost of development services revenue of $78 and $260 for the three and nine months ended September 30, 2025 and $143 and $259 for the three and nine months ended September 30, 2024, respectively.