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Deferred Revenue - Additional Information (Details) - USD ($) $ in Thousands		3 Months Ended		12 Months Ended
	Mar. 31, 2021	Mar. 31, 2021	Mar. 31, 2020	Dec. 31, 2020
Disaggregation Of Revenue [Line Items]
Current deferred revenue	$ 78,348	$ 78,348		$ 73,319
Deferred revenue, less current portion	144,356	144,356		163,618
Revenue recognized	19,000	(21,351)
MRD Development Agreements
Disaggregation Of Revenue [Line Items]
Revenue recognized		7,200	$ 400
Development Revenue
Disaggregation Of Revenue [Line Items]
Current deferred revenue	61,157	61,157		57,856
Deferred revenue, less current portion	143,694	143,694		162,894
Development Revenue | Genentech, Inc.
Disaggregation Of Revenue [Line Items]
Current deferred revenue	58,600	58,600		55,100
Deferred revenue, less current portion	137,900	137,900		157,000
Sequencing Revenue
Disaggregation Of Revenue [Line Items]
Current deferred revenue	17,191	17,191		15,463
Deferred revenue, less current portion	$ 662	662		724
Revenue recognized		200
Medicare | Specific Patients
Disaggregation Of Revenue [Line Items]
Revenue recognized				$ 200
Anticipated Samples | MRD Development Agreements
Disaggregation Of Revenue [Line Items]
Revenue recognized		$ 400

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