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Equity Incentive Plans - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |
Weighted-average remaining contractual life options outstanding | 7 years |  |
Weighted-average remaining contractual life vested and exercisable options outstanding | 5 years 8 months 12 days |  |
Weighted-average grant date fair value | $ 24.22 | $ 21.11 | $ 6.87
Total intrinsic value of options exercised | $ 156,500 | $ 190,400 | $ 39,100
Proceeds from exercise of stock options | 26,717 | 21,748 | $ 4,055
Proceeds from settlement of stock option exercised in prior periods | 300 | $ 500 |
Unrecognized share-based compensation expense related to unvested stock options | $ 96,800 |  |
Unrecognized share-based compensation expense related to unvested stock options, weighted-average period for recognition | 2 years 10 months 24 days |  |
Option Valuation Model |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |
Expected dividend yield | 0.00% |  |
Restricted Stock Units (RSUs) |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |
Unrecognized share-based compensation expense related to unvested stock options, weighted-average period for recognition | 3 years 4 months 24 days |  |
Unrecognized share-based compensation expense related to unvested RSUs | $ 38,300 |  |
Sequenta 2008 Stock Plan |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |
Shares available for future issuance | 0 |  |
Equity awards outstanding | 0 |  |
2009 Equity Incentive Plan | Grant |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |
Shares available for future issuance | 0 |  |
2009 Equity Incentive Plan | Grant | Maximum |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |
Option expiration period | 10 years |  |
2019 Equity Incentive Plan |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |
Shares available for future issuance | 22,299,923 | 18,617,001 |
2019 Equity Incentive Plan | Grant |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |
Number of shares authorized for issuance | 29,131,628 |  |
2019 Equity Incentive Plan | Grant | Non Employee Directors |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |
Vesting period | 4 years |  |
2019 Equity Incentive Plan | Grant | Maximum |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |
Option expiration period | 10 years |  |
2019 Equity Incentive Plan | Restricted Stock Units (RSUs) |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |
Weighted-average grant date fair value | $ 37.98 | $ 28.10 | $ 41.63

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- Definition Share based compensation arrangement by share based payment award vested and exercisable options outstanding weighted average remaining contractual term. + References No definition available. + Details
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- Definition Weighted-average period over which cost not yet recognized is expected to be recognized for award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (i) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Amount of cost to be recognized for nonvested award under share-based payment arrangement. Excludes share and unit options. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (i) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The weighted average fair value at grant date for nonvested equity-based awards issued during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan). + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2)(iii)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(iii) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Period from grant date that an equity-based award expires, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (a)(2) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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