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Deferred Revenue - Additional Information (Details) - USD ($) $ in Thousands		12 Months Ended
	Dec. 31, 2021	Dec. 31, 2021	Dec. 31, 2020
Disaggregation Of Revenue [Line Items]
Current deferred revenue	$ 80,460	$ 80,460	$ 73,319
Deferred revenue, less current portion	98,750	98,750	163,618
Revenue recognized	75,700	(95,789)
Development Revenue
Disaggregation Of Revenue [Line Items]
Current deferred revenue	58,545	58,545	57,856
Deferred revenue, less current portion	98,576	98,576	162,894
Development Revenue | Genentech, Inc.
Disaggregation Of Revenue [Line Items]
Current deferred revenue	56,100	56,100	55,100
Deferred revenue, less current portion	94,000	94,000	157,000
Sequencing Revenue
Disaggregation Of Revenue [Line Items]
Current deferred revenue	21,915	21,915	15,463
Deferred revenue, less current portion	$ 174	174	$ 724
Revenue recognized		3,600
Medicare | Specific Patients
Disaggregation Of Revenue [Line Items]
Revenue recognized		$ 2,500

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