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Revenue - Additional Information (Details) - USD ($) | 1 Months Ended | 3 Months Ended
--- | --- | ---
Feb. 28, 2019 | Mar. 31, 2022 | Mar. 31, 2021
Disaggregation Of Revenue [Line Items] |  |  |
Revenue from collaboration agreement |  | $ 38,620,000 | $ 38,442,000
Medicare Reimbursements |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Revenue from collaboration agreement |  | 1,400,000 | 800,000
Medicare Reimbursements | Immune Medicine Service Revenue |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Revenue from collaboration agreement |  | 200,000 |
Medicare Reimbursements | MRD Service Revenue |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Revenue from collaboration agreement |  | 1,200,000 |
M R D Development Agreements | Maximum |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Additional milestone payment receivable |  | 330,500,000 |
Genentech Collaboration Agreement |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Revenue from collaboration agreement |  | 12,300,000 | $ 15,600,000
Non-refundable upfront payments received | $ 300,000,000.0 | $ 300,000,000.0 |
Genentech Collaboration Agreement | Maximum |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Revenue recognition expected period |  | 8 years |
Genentech Collaboration Agreement | Maximum | Regulatory Milestones |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Expected revenue through milestone payments |  | $ 75,000,000.0 |
Genentech Collaboration Agreement | Maximum | Development Milestones |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Expected revenue through milestone payments |  | 300,000,000.0 |
Genentech Collaboration Agreement | Maximum | Commercial Milestones |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Expected revenue through milestone payments |  | 1,430,000,000.0 |
Genentech Collaboration Agreement | Minimum |  |  |
Disaggregation Of Revenue [Line Items] |  |  |
Expected revenue through milestone payments |  | $ 1,800,000 |
Revenue recognition expected period |  | 7 years |

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