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Equity Incentive Plans - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Weighted-average remaining contractual life stock options outstanding 7 years 3 months 18 days    
Weighted-average remaining contractual life vested and exercisable stock options 5 years 4 months 24 days    
Proceeds from exercise of stock options $ 2,749 $ 14,185  
Proceeds from settlement of stock option exercised in prior periods   300  
Unsettled cash proceeds related to stock options exercised   $ 500  
Grant date fair value $ 7.81 $ 27.67  
Recognized share-based compensation expense $ 12,861 $ 8,484  
Option Valuation Model      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected dividend yield 0.00%    
Monte Carlo Valuation Model      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Recognized share-based compensation expense $ 4,700    
Requisite service period term 3 years    
Market-Based Restricted Stock Units | Monte Carlo Valuation Model      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Grant date fair value $ 18.89    
Market-Based Restricted Stock Units | Chief Executive Officer      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Performance period term 3 years    
Market-Based Restricted Stock Units | Minimum | Chief Executive Officer      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Common stock that may be earned under the award 0    
Market-Based Restricted Stock Units | Maximum | Chief Executive Officer      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Common stock that may be earned under the award 494,234    
Restricted Stock Units (RSUs)      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Grant date fair value $ 12.17 $ 44.10  
2009 Equity Incentive Plan | Grant      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Shares available for future issuance 0    
2009 Equity Incentive Plan | Grant | Maximum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Option expiration period 10 years    
2019 Equity Incentive Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Shares available for future issuance 14,500,039   22,299,923
2019 Equity Incentive Plan | Grant      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Number of shares authorized for issuance 29,213,355    
2019 Equity Incentive Plan | Grant | Non Employee Directors      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Vesting period 4 years    
2019 Equity Incentive Plan | Grant | Maximum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Option expiration period 10 years    
2019 Equity Incentive Plan | Restricted Stock Units (RSUs)      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Grant date fair value $ 12.17