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Property and Equipment, Net | 12 Months Ended
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Dec. 31, 2022
Property, Plant and Equipment [Abstract] |
Property and Equipment, Net | 7. Property and Equipment, Net Property and equipment, net as of December 31, 2022 and 2021 consisted of the following (in thousands):
|  | December 31, |
|  | 2022 |  |  | 2021 |
Laboratory equipment |  | $ | 43,592 |  |  | $ | 36,312 |
Computer equipment |  |  | 7,766 |  |  |  | 6,988 |
Furniture and office equipment |  |  | 5,342 |  |  |  | 5,579 |
Computer software |  |  | 1,069 |  |  |  | 992 |
Construction in progress |  |  | 7,625 |  |  |  | 5,658 |
Leasehold improvements |  |  | 72,403 |  |  |  | 65,959 |
Total property and equipment, at cost |  |  | 137,797 |  |  |  | 121,488 |
Less: Accumulated depreciation |  |  | (54,350 | ) |  |  | (36,226 | )
Property and equipment, net |  | $ | 83,447 |  |  | $ | 85,262 |
Depreciation expense was $19.2 million, $12.3 million and $6.8 million for the year ended December 31, 2022, 2021 and 2020, respectively.

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- Definition The entire disclosure for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 6 -URI https://asc.fasb.org/extlink&oid=126982197&loc=d3e99893-112916 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -URI https://asc.fasb.org/topic&trid=2155823 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 7 -URI https://asc.fasb.org/extlink&oid=126982197&loc=SL120174063-112916 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 1 -Subparagraph (d) -URI https://asc.fasb.org/extlink&oid=126982197&loc=d3e99779-112916 + Details
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