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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Operating activities    
Net loss $ (105,511) $ (114,880)
Adjustments to reconcile net loss to net cash used in operating activities    
Depreciation expense 10,234 9,409
Noncash lease expense 3,635 3,597
Share-based compensation expense 32,016 27,041
Intangible assets amortization 842 842
Investment amortization (3,527) 1,414
Inventory reserve 757 2,769
Noncash interest expense 2,807  
Other 65 (19)
Changes in operating assets and liabilities    
Accounts receivable, net 8,464 (6,303)
Inventory (6,542) (2,284)
Prepaid expenses and other current assets 366 644
Accounts payable and accrued liabilities (7,938) (8,956)
Operating lease right-of-use assets and liabilities (4,462) (715)
Deferred revenue (13,902) (24,174)
Other (12) 97
Net cash used in operating activities (82,708) (111,518)
Investing activities    
Purchases of property and equipment (6,621) (8,375)
Purchases of marketable securities (188,479) (85,191)
Proceeds from maturities of marketable securities 295,402 136,000
Net cash provided by investing activities 100,302 42,434
Financing activities    
Proceeds from exercise of stock options 2,141 6,739
Net cash provided by financing activities 2,141 6,739
Net increase (decrease) in cash, cash equivalents and restricted cash 19,735 (62,345)
Cash, cash equivalents and restricted cash at beginning of year 92,428 141,203
Cash, cash equivalents and restricted cash at end of period 112,163 78,858
Noncash investing activities    
Purchases of equipment included in accounts payable and accrued liabilities 1,291 $ 3,286
Supplemental disclosure of cash flow information    
Cash paid for interest $ 4,642