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Segment Information - Schedule of Segment Information (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2024 | Jun. 30, 2023 | Jun. 30, 2024 | Jun. 30, 2023
Segment Reporting Information [Line Items] |  |  |  |  |  |
Revenue |  | $ 43,190 | $ 48,926 | $ 85,063 | $ 86,573 |
Operating expenses |  | 90,508 | 96,744 | 181,143 | 191,584 |
Adjusted EBITDA | [1] | (21,446) | (24,819) | (49,626) | (61,917) | [2]
Net loss |  | (46,248) | (47,811) | (93,781) | (105,511) |
Net loss attributable to noncontrolling interest |  | 26 | 1 | 52 | 2 |
Net loss attributable to Adaptive Biotechnologies Corporation |  | (46,222) | (47,810) | (93,729) | (105,509) |
Interest and other income, net |  | (3,766) | (3,612) | (7,988) | (6,636) |
Interest expense | [3] | 2,696 | 3,605 | 5,689 | 7,136 |
Depreciation and amortization expense |  | 5,003 | 5,653 | 10,217 | 11,076 |
Impairment of long-lived assets | [4] | 7,205 |  | 7,205 |  |
Restructuring expense | [4] | 680 |  | 1,724 |  |
Share-based compensation expense | [2] | 12,958 | 17,345 | 27,256 | 32,016 |
Operating Segments | MRD |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |
Revenue |  | 35,284 | 25,882 | 67,910 | 47,309 |
Operating expenses |  | 58,361 | 58,944 | 118,247 | 114,969 |
Adjusted EBITDA | [1] | (11,289) | (23,079) | (28,548) | (49,465) | [2]
Net loss |  | (23,077) | (33,063) | (50,337) | (67,660) |
Net loss attributable to Adaptive Biotechnologies Corporation |  | (23,077) | (33,063) | (50,337) | (67,660) |
Depreciation and amortization expense |  | 2,604 | 2,267 | 5,305 | 4,323 |
Impairment of long-lived assets | [4] | 2,819 |  | 2,819 |  |
Restructuring expense | [4] | 561 |  | 1,028 |  |
Share-based compensation expense | [2] | 5,804 | 7,717 | 12,637 | 13,872 |
Operating Segments | IM |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |
Revenue |  | 7,906 | 23,044 | 17,153 | 39,264 |
Operating expenses |  | 26,133 | 30,681 | 49,974 | 62,353 |
Adjusted EBITDA | [1] | (7,033) | 1,264 | (13,960) | (6,163) | [2]
Net loss |  | (18,228) | (7,636) | (32,821) | (23,088) |
Net loss attributable to Adaptive Biotechnologies Corporation |  | (18,228) | (7,636) | (32,821) | (23,088) |
Depreciation and amortization expense |  | 1,967 | 2,608 | 4,049 | 5,361 |
Impairment of long-lived assets | [4] | 4,386 |  | 4,386 |  |
Restructuring expense | [4] | 119 |  | 696 |  |
Share-based compensation expense | [2] | 4,723 | 6,292 | 9,730 | 11,564 |
Unallocated Corporate |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |
Operating expenses |  | 6,014 | 7,119 | 12,922 | 14,262 |
Adjusted EBITDA | [1] | (3,124) | (3,004) | (7,118) | (6,289) | [2]
Net loss |  | (4,943) | (7,112) | (10,623) | (14,763) |
Net loss attributable to noncontrolling interest |  | 26 | 1 | 52 | 2 |
Net loss attributable to Adaptive Biotechnologies Corporation |  | (4,917) | (7,111) | (10,571) | (14,761) |
Interest and other income, net |  | (3,766) | (3,612) | (7,988) | (6,636) |
Interest expense | [3] | 2,696 | 3,605 | 5,689 | 7,136 |
Depreciation and amortization expense |  | 432 | 778 | 863 | 1,392 |
Share-based compensation expense | [2] | $ 2,431 | $ 3,336 | $ 4,889 | $ 6,580 |
[1] | Adjusted EBITDA is a non-GAAP financial measure. See “Management's Discussion and Analysis of Financial Condition and Results of Operations—Adjusted EBITDA” for an explanation for how it is calculated and used by management.
[2] | Represents share-based compensation expense related to stock option, restricted stock unit and market-based restricted stock unit awards. See Note 11, Equity Incentive Plans for details on our share-based compensation expense.
[3] | Represents costs associated with our revenue interest liability and noncash interest costs associated with the amortization of the related deferred issuance costs. See Note 8, Revenue Interest Purchase Agreement for details on the Purchase Agreement.
[4] | Represents expenses recognized in conjunction with restructuring activities. See Note 12, Restructurings for details on our restructuring expenses.

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