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v3.25.2

Segment Information - Schedule of Segment Information, Including Significant Segment Expenses (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2025 | Jun. 30, 2024 | Jun. 30, 2025 | Jun. 30, 2024
Segment Reporting Information [Line Items] |  |  |  |  |
Revenue |  | $ 58,879 | $ 43,190 | $ 111,322 | $ 85,063
Cost of revenue |  | 17,999 | 19,317 | 34,978 | 37,368
Research and development |  | 24,134 | 25,353 | 48,337 | 55,598
Sales and marketing |  | 23,573 | 20,314 | 46,620 | 42,633
General and administrative |  | 17,786 | 17,895 | 35,185 | 37,492
Share-based compensation expense |  | (13,359) | (12,958) | (25,506) | (27,256)
Restructuring expense | [1] |  | (680) |  | (1,724)
Impairment of long-lived assets | [1] |  | (7,205) |  | (7,205)
Depreciation and amortization expense |  | (4,071) | (4,571) | (8,376) | (9,354)
Other unallocated items | [2] | (6,058) | (4,943) | (12,169) | (10,623)
Net loss |  | (25,593) | (46,248) | (55,423) | (93,781)
Operating Segments |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |
Revenue |  | 58,879 | 43,190 | 111,322 | 85,063
Cost of revenue |  | 16,535 | 16,863 | 32,420 | 32,784
Research and development |  | 24,134 | 25,353 | 48,337 | 55,598
Sales and marketing |  | 21,954 | 18,658 | 43,367 | 39,043
General and administrative |  | 10,131 | 9,976 | 19,633 | 20,632
Items to reconcile net loss to Adjusted EBITDA | [3] | 15,378 | 22,983 | 29,540 | 40,650
Adjusted EBITDA | [3] | (4,157) | (18,322) | (13,714) | (42,508)
Operating Segments | MRD |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |
Revenue |  | 49,938 | 35,284 | 93,659 | 67,910
Cost of revenue |  | 16,535 | 16,863 | 32,420 | 32,784
Research and development |  | 8,498 | 10,045 | 17,657 | 22,969
Sales and marketing |  | 21,954 | 18,658 | 43,367 | 39,043
General and administrative |  | 10,131 | 9,976 | 19,633 | 20,632
Items to reconcile net loss to Adjusted EBITDA | [3] | 9,092 | 11,788 | 17,219 | 21,789
Adjusted EBITDA | [3] | 1,912 | (11,289) | (2,199) | (28,548)
Operating Segments | Immune Medicine |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |
Revenue |  | 8,941 | 7,906 | 17,663 | 17,153
Research and development |  | 15,636 | 15,308 | 30,680 | 32,629
Items to reconcile net loss to Adjusted EBITDA | [3] | 6,286 | 11,195 | 12,321 | 18,861
Adjusted EBITDA | [3] | (6,069) | (7,033) | (11,515) | (13,960)
Operating Segments | MRD and Immune Medicine |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |
Share-based compensation expense | [4] | (11,307) | (10,527) | (21,164) | (22,367)
Unallocated Corporate |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |
Other segment items | [5] | 5,660 | 13,645 | 10,819 | 20,164
Unallocated Corporate | MRD |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |
Other segment items | [5] |  | 2,819 |  | 2,819
Unallocated Corporate | Immune Medicine |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |
Other segment items | [5] | $ 5,660 | $ 10,826 | $ 10,819 | $ 17,345
[1] | Represents expenses recognized in conjunction with restructuring activities. See Note 12, Restructurings for details on our restructuring expense.
[2] | Represents unallocated expenses and income not included in the measurements reviewed by the CODM to assess each segment's performance.
[3] | Adjusted EBITDA is a non-GAAP financial measure. See “Management's Discussion and Analysis of Financial Condition and Results of Operations—Adjusted EBITDA” for an explanation of how it is calculated and used by management.
[4] | Represents share-based compensation expense related to stock option, restricted stock unit and market-based restricted stock unit awards. See Note 11, Equity Incentive Plans for details on our share-based compensation expense.
[5] | For the MRD segment, includes MRD expenses related to the impairment of long-lived assets. For the Immune Medicine segment, includes all Immune Medicine operating expenses, other than research and development expenses.

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