<SEC-DOCUMENT>0001950047-25-009303.txt : 20251124
<SEC-HEADER>0001950047-25-009303.hdr.sgml : 20251124
<ACCEPTANCE-DATETIME>20251124165814
ACCESSION NUMBER:		0001950047-25-009303
CONFORMED SUBMISSION TYPE:	144/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20251124
DATE AS OF CHANGE:		20251124

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Adaptive Biotechnologies Corp
		CENTRAL INDEX KEY:			0001478320
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				270907024
		STATE OF INCORPORATION:			WA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		144/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	001-38957
		FILM NUMBER:		251513989

	BUSINESS ADDRESS:	
		STREET 1:		1165 EASTLAKE AVE E
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98109
		BUSINESS PHONE:		206-659-0067

	MAIL ADDRESS:	
		STREET 1:		1165 EASTLAKE AVE E
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98109

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Adaptive TCR Corp
		DATE OF NAME CHANGE:	20091209

REPORTING-OWNER:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BENZENO SHARON
		CENTRAL INDEX KEY:			0001780854
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		144/A

	MAIL ADDRESS:	
		STREET 1:		C/O ADAPTIVE BIOTECHNOLOGIES CORPORATION
		STREET 2:		1551 EASTLAKE AVE E STE 200
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98102
</SEC-HEADER>
<DOCUMENT>
<TYPE>144/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144/A</submissionType>
    <previousAccessionNumber>0001950047-25-009206</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001780854</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001478320</issuerCik>
      <issuerName>Adaptive Biotechnologies Corp</issuerName>
      <secFileNumber>001-38957</secFileNumber>
      <issuerAddress>
        <com:street1>1165 EASTLAKE AVE E</com:street1>
        <com:city>SEATTLE</com:city>
        <com:stateOrCountry>WA</com:stateOrCountry>
        <com:zipCode>98109</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>206-659-0067</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>BENZENO SHARON</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Morgan Stanley Smith Barney LLC Executive Financial Services </name>
        <address>
          <com:street1>1 New York Plaza 8th Floor</com:street1>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10004</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>308477</noOfUnitsSold>
      <aggregateMarketValue>5034344.64</aggregateMarketValue>
      <noOfUnitsOutstanding>152665188</noOfUnitsOutstanding>
      <approxSaleDate>11/21/2025</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>11/21/2025</acquiredDate>
      <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>308477</amountOfSecuritiesAcquired>
      <paymentDate>11/21/2025</paymentDate>
      <natureOfPayment>Cash</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>10b5-1 Sales for SHARON BENZENO </name>
        <address>
          <com:street1>1165 Eastlake Avenue </com:street1>
          <com:city>Seattle</com:city>
          <com:stateOrCountry>WA</com:stateOrCountry>
          <com:zipCode>98109</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>11/20/2025</saleDate>
      <amountOfSecuritiesSold>297925</amountOfSecuritiesSold>
      <grossProceeds>4928722.24</grossProceeds>
    </securitiesSoldInPast3Months>
    <remarks>The Form 144 was amended to update the amount sold on 11/21/2025.</remarks>
    <noticeSignature>
      <noticeDate>11/24/2025</noticeDate>
      <planAdoptionDates>
        <planAdoptionDate>08/18/2025</planAdoptionDate>
      </planAdoptionDates>
      <signature>/s/ Sharon Benzeno</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
