<SEC-DOCUMENT>0000784199-16-000312.txt : 20161114
<SEC-HEADER>0000784199-16-000312.hdr.sgml : 20161111
<ACCEPTANCE-DATETIME>20161114090256
ACCESSION NUMBER:		0000784199-16-000312
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20161114
DATE AS OF CHANGE:		20161114

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CRYOLIFE INC
		CENTRAL INDEX KEY:			0000784199
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				592417093
		STATE OF INCORPORATION:			FL
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-214583
		FILM NUMBER:		161990999

	BUSINESS ADDRESS:	
		STREET 1:		1655 ROBERTS BOULEVARD N W
		CITY:			KENNESAW
		STATE:			GA
		ZIP:			30144
		BUSINESS PHONE:		7704193355

	MAIL ADDRESS:	
		STREET 1:		1655 ROBERTS BOULEVARD N W
		CITY:			KENNESAW
		STATE:			GA
		ZIP:			30144
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3
<SEQUENCE>1
<FILENAME>c199-20161114xs3.htm
<DESCRIPTION>S-3
<TEXT>
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		<title>
			S-3 Amendment
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			<a name="_GoBack"></a><font style="display: inline;">As filed with the Securities and </font><font style="display: inline;">Ex</font><font style="display: inline;">change Commission on November 11</font><font style="display: inline;">, 2016</font>
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		<p style="margin:0pt 0pt 10pt;border-bottom:2pt double #000000 ;text-align:right;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">Registration No. </font><font style="display: inline;">333-</font><font style="display: inline;">&nbsp;</font><font style="display: inline;">210046</font>
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		<p style="margin:0pt;text-align:center;font-weight:bold;font-family:Times New Roman;font-size: 14pt">
			<font style="display: inline;">UNITED STATES</font><br /><font style="display: inline;">SECURITIES AND EXCHANGE COMMISSION</font>
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		<p style="margin:0pt;text-align:center;font-weight:bold;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">Washington, D.C. 20549</font>
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		<p style="margin:0pt 0pt 5pt 180pt;font-family:Times New Roman;font-size: 10pt">
			<font style="text-indent:0pt;margin-left:0pt; overflow: hidden; white-space: nowrap;">_____________________________________________________________________________________</font><font style="text-indent:0pt;margin-left:0pt;text-align:right"><font style="display: inline;"></font></font>
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		<p style="margin:0pt;text-align:center;font-weight:bold;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">POST-EFFECTIVE AMENDMENT</font><font style="display: inline;font-size:10pt;"> NO. 2</font>
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			<font style="display: inline;">TO</font>
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		<p style="margin:0pt;border-top:1pt none #D9D9D9 ;text-align:center;font-weight:bold;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">FORM S-3</font><br /><font style="display: inline;">REGISTRATION STATEMENT</font>
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		<p style="margin:0pt;text-align:center;font-weight:bold;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-style:italic;">UNDER</font><br /><font style="display: inline;font-style:italic;">THE SECURITIES ACT OF 1933</font>
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			<font style="text-indent:0pt;margin-left:0pt; overflow: hidden; white-space: nowrap;">_____________________________________________________________________________________</font><font style="text-indent:0pt;margin-left:0pt;text-align:right"><font style="display: inline;"></font></font>
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		<div style="width:100%"><table cellpadding="0" cellspacing="0" align="center" style="border-collapse:collapse;width:468.00pt;margin-left:0pt;">
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					<p style="margin:0pt;font-family:Times New Roman;height:1.00pt;overflow:hidden;font-size: 1pt">
						<font style="display: inline;font-size:1pt;">&#xFEFF;</font></p>
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					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 16pt">
						<font style="display: inline;font-weight:bold;font-size:16pt;">CryoLife, Inc.</font></p>
				</td>
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				<td valign="bottom" style="width:468.00pt;padding:0pt 6.9pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
						<font style="display: inline;font-size:8.5pt;">(Exact Name of Registrant as Specified in its Charter)</font></p>
				</td>
			</tr>
		</table></div>
		<p style="margin:0pt 0pt 10pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">&#xFEFF;</font>
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			<font style="text-indent:0pt;margin-left:0pt; overflow: hidden; white-space: nowrap;"><font style="display: inline;">&nbsp;</font>___________________________________________________________________________________</font><font style="text-indent:0pt;margin-left:0pt;text-align:right"><font style="display: inline;"></font></font>
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						&nbsp;</p>
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					<p style="margin:0pt;text-indent:18pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
						<font style="display: inline;font-weight:bold;font-size:8.5pt;">Florida</font></p>
				</td>
				<td valign="bottom" style="width:234.00pt;padding:0pt 6.9pt;">
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;font-size:10pt;">59-2417093</font></p>
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					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
						<font style="display: inline;font-size:8.5pt;">(State or Other Jurisdiction </font><br /><font style="display: inline;font-size:8.5pt;">of Incorporation or Organization)</font></p>
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					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
						<font style="display: inline;font-size:8.5pt;">(I.R.S. Employer </font><br /><font style="display: inline;font-size:8.5pt;">Identification No.)</font></p>
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					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
						<font style="display: inline;font-size:8.5pt;">&#xFEFF;</font></p>
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					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						&nbsp;</p>
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					<p style="margin:6pt 0pt 0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;font-size:10pt;">1655 Roberts Boulevard, NW </font></p>
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;font-size:10pt;">Kennesaw, Georgia 30144 </font></p>
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;font-size:10pt;">(770) 419-3355 </font></p>
					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 9pt">
						&nbsp;</p>
				</td>
			</tr>
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					<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
						<font style="display: inline;font-size:8.5pt;">(Address, Including Zip Code, and Telephone Number, Including Area Code, of Registrant</font><font style="display: inline;font-size:8.5pt;">&#x2019;</font><font style="display: inline;font-size:8.5pt;">s Principal Executive Offices)</font></p>
				</td>
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		<p style="margin:0pt 0pt 10pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">&#xFEFF;</font>
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		<p style="margin:0pt 0pt 5pt 180pt;font-family:Times New Roman;font-size: 10pt">
			<font style="text-indent:0pt;margin-left:0pt; overflow: hidden; white-space: nowrap;">_____________________________________________________________________________________</font><font style="text-indent:0pt;margin-left:0pt;text-align:right"><font style="display: inline;"></font></font>
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		<p style="margin:6pt 0pt 0pt;text-align:center;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">J. Patrick Mackin, </font>
		</p>
		<p style="margin:0pt;text-align:center;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">Chairman, President and </font>
		</p>
		<p style="margin:0pt;text-align:center;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">Chief Executive Officer </font>
		</p>
		<p style="margin:0pt;text-align:center;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">CryoLife, Inc. </font>
		</p>
		<p style="margin:0pt;text-align:center;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">1655 Roberts Boulevard, NW </font>
		</p>
		<p style="margin:0pt;text-align:center;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">Kennesaw, Georgia 30144 </font>
		</p>
		<p style="margin:0pt;text-align:center;border-top:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">(770) 419-3355 </font>
		</p>
		<p style="margin:0pt;text-align:center;font-weight:bold;font-family:Times New Roman;font-size: 8pt">
			<font style="display: inline;font-size:8.5pt;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 8pt">
			<font style="display: inline;font-size:8.5pt;">(Name, Address, Including Zip Code, and Telephone Number, Including Area Code, of Agent for Service)</font>
		</p>
		<p style="margin:0pt 0pt 5pt 180pt;font-family:Times New Roman;font-size: 10pt">
			<font style="text-indent:0pt;margin-left:0pt; overflow: hidden; white-space: nowrap;">_____________________________________________________________________________________</font><font style="text-indent:0pt;margin-left:0pt;text-align:right"><font style="display: inline;"></font></font>
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		<p style="margin:0pt;border-bottom:1pt none #D9D9D9 ;text-align:center;font-weight:bold;font-family:Times New Roman;font-size: 8pt">
			<font style="display: inline;font-style:italic;font-size:8.5pt;">Copies to:</font>
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		<p style="margin:0pt;border-top:1pt none #D9D9D9 ;text-align:center;font-weight:bold;font-family:Times New Roman;font-size: 8pt">
			<font style="display: inline;font-size:8.5pt;">Paul Tobias</font><font style="display: inline;font-size:8.5pt;">&nbsp;</font><br /><font style="display: inline;font-size:8.5pt;">Vinson &amp; Elkins L.L.P.</font><br /><font style="display: inline;font-size:8.5pt;"></font><font style="display: inline;font-size:8.5pt;">2801 Via Fortuna</font><font style="display: inline;font-size:8.5pt;">, &nbsp;</font><font style="display: inline;font-size:8.5pt;">Suite 100</font><br /><font style="display: inline;font-size:8.5pt;"></font><font style="display: inline;font-size:8.5pt;">Austin, Texas 78746</font><br /><font style="display: inline;font-size:8.5pt;">Tel: (5</font><font style="display: inline;font-size:8.5pt;">12) </font><font style="display: inline;font-size:8.5pt;">542-8400</font><br /><font style="display: inline;font-size:8.5pt;"></font><font style="display: inline;font-size:8.5pt;">Fax: (</font><font style="display: inline;font-size:8.5pt;">512</font><font style="display: inline;font-size:8.5pt;">) &nbsp;</font><font style="display: inline;font-size:8.5pt;">236</font><font style="display: inline;font-size:8.5pt;">&nbsp;</font><font style="display: inline;font-size:8.5pt;">-</font><font style="display: inline;font-size:8.5pt;"> 3266</font><font style="display: inline;font-size:8.5pt;"> &nbsp;&nbsp; </font>
		</p>
		<p style="margin:0pt 0pt 5pt 180pt;font-family:Times New Roman;font-size: 10pt">
			<font style="text-indent:0pt;margin-left:0pt; overflow: hidden; white-space: nowrap;">_____________________________________________________________________________________</font><font style="text-indent:0pt;margin-left:0pt;text-align:right"><font style="display: inline;"></font></font>
		</p>
		<p style="margin:0pt;text-indent:18pt;font-family:Times New Roman;font-size: 8pt">
			<font style="display: inline;font-size:8.5pt;">Approximate date of commencement of proposed sale to the public: From time to time after the effective date of this registration statement as determined by market conditions and other factors.</font>
		</p>
		<p style="margin:0pt 0pt 5pt 180pt;font-family:Times New Roman;font-size: 10pt">
			<font style="text-indent:0pt;margin-left:0pt; overflow: hidden; white-space: nowrap;">_____________________________________________________________________________________</font><font style="text-indent:0pt;margin-left:0pt;text-align:right"><font style="display: inline;"></font></font>
		</p>
		<p style="margin:0pt 0pt 3pt;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 8pt">
			<font style="display: inline;font-size:8.5pt;">If the only securities being registered on this Form are being offered pursuant to dividend or interest reinvestment plans, please check the following box: </font><font style="display: inline;font-size:8.5pt;">&#x2610;</font>
		</p>
		<p style="margin:0pt 0pt 3pt;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 8pt">
			<font style="display: inline;font-size:8.5pt;">If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, other than securities offered only in connection with dividend or interest reinvestment plans, check the following box: </font><font style="display: inline;font-size:8.5pt;">&#x2610;</font>
		</p>
		<p style="margin:0pt 0pt 3pt;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 8pt">
			<font style="display: inline;font-size:8.5pt;">If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. </font><font style="display: inline;font-size:8.5pt;">&#x2610;</font>
		</p>
		<p style="margin:0pt 0pt 3pt;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 8pt">
			<font style="display: inline;font-size:8.5pt;">If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. </font><font style="display: inline;font-size:8.5pt;">&#x2610;</font>
		</p>
		<p style="margin:0pt 0pt 3pt;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 8pt">

		</p>
		<p><font size="1"> </font></p><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p>
		<p style="margin:0pt 0pt 3pt;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;;font-size: 8pt"><font style="display: inline;font-size:8.5pt;">If this Form is a registration statement pursuant to General Instruction I.D. or a post-effective amendment thereto that shall become effective upon filing with the Commission pursuant to Rule 462(e) under the Securities Act, check the following box. </font><font style="display: inline;font-size:8.5pt;">&#x2610;</font>
		</p>
		<p style="margin:0pt 0pt 3pt;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 8pt">
			<font style="display: inline;font-size:8.5pt;">If this Form is a post-effective amendment to a registration statement filed pursuant to General Instruction I.D. filed to register additional securities or additional classes of securities pursuant to Rule 413(b) under the Securities Act, check the following box. </font><font style="display: inline;font-size:8.5pt;">&#x2610;</font>
		</p>
		<p style="margin:0pt 0pt 3pt;border-top:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 8pt">
			<font style="display: inline;font-size:8.5pt;">Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of </font><font style="display: inline;font-size:8.5pt;">&#x201C;</font><font style="display: inline;font-size:8.5pt;">large accelerated filer,</font><font style="display: inline;font-size:8.5pt;">&#x201D;</font><font style="display: inline;font-size:8.5pt;">&nbsp;</font><font style="display: inline;font-size:8.5pt;">&#x201C;</font><font style="display: inline;font-size:8.5pt;">accelerated filer</font><font style="display: inline;font-size:8.5pt;">&#x201D;</font><font style="display: inline;font-size:8.5pt;"> and </font><font style="display: inline;font-size:8.5pt;">&#x201C;</font><font style="display: inline;font-size:8.5pt;">smaller reporting company</font><font style="display: inline;font-size:8.5pt;">&#x201D;</font><font style="display: inline;font-size:8.5pt;"> in Rule 12b-2 of the Exchange Act.</font>
		</p>
		<p style="margin:0pt;border-bottom:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 8pt">
			<font style="text-indent:0pt;margin-left:0pt; padding-right:338pt;"><font style="display: inline;font-size:8.5pt;">Large accelerated filer&nbsp;</font><font style="display: inline;font-size:8.5pt;">&#x2610;</font></font><font style="text-indent:0pt;margin-left:0pt; padding-right:4pt;text-align:right"><font style="display: inline;font-size:8.5pt;">Accelerated filer&nbsp;</font><font style="display: inline;font-family:MS Gothic;font-size:8.5pt;">&#x2612;</font></font>
		</p>
		<p style="margin:0pt;border-top:1pt none #D9D9D9 ;font-family:Times New Roman;font-size: 8pt">
			<font style="text-indent:0pt;margin-left:0pt; padding-right:401pt;"><font style="display: inline;font-size:8.5pt;">Non-accelerated filer&nbsp;</font><font style="display: inline;font-size:8.5pt;">&#x2610;</font><font style="display: inline;font-size:8.5pt;"> (Do not check if a smaller reporting company)</font></font><font style="text-indent:0pt;margin-left:0pt; padding-right:4pt;text-align:right"><font style="display: inline;font-size:8.5pt;">Smaller reporting company&nbsp;</font><font style="display: inline;font-size:8.5pt;">&#x2610;</font></font>
		</p></div><div style="margin-left:72pt;margin-right:72pt;">
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		</p>

		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">

			<font style="font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;font-size:9pt;"></font><font style="display: inline;"></font><font style="display: inline;">2</font><font style="display: inline;"></font>

		</p>

</div><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p>
		<p style="margin:0pt 0pt 10pt;text-align:center;font-weight:bold;font-family:Times New Roman;;font-size: 10pt"><font style="display: inline;">DEREGISTRATION OF SECURITIES</font>
		</p>
		<p style="margin:0pt 0pt 10pt;border-bottom:1pt none #D9D9D9 ;text-indent:18pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">This Post-Effective Amendment</font><font style="display: inline;"> No. 2</font><font style="display: inline;"> (this &#x201C;Post Effective Amendment&#x201D;)</font><font style="display: inline;"> relates to the Registration Statement of </font><font style="display: inline;">CryoLife, Inc.</font><font style="display: inline;"> &nbsp;(</font><font style="display: inline;">the &#x201C;</font><font style="display: inline;">Company</font><font style="display: inline;">&#x201D;</font><font style="display: inline;">) &nbsp;</font><font style="display: inline;">on Form S-3 (File No. 333-</font><font style="display: inline;">&nbsp;</font><font style="display: inline;">210046</font><font style="display: inline;">) filed with the Securities and Exchange Commission (the </font><font style="display: inline;">&#x201C;</font><font style="display: inline;">SEC</font><font style="display: inline;">&#x201D;</font><font style="display: inline;">) on </font><font style="display: inline;">March 23, 2016</font><font style="display: inline;"> and declared effective by the SEC</font><font style="display: inline;"> on </font><font style="display: inline;">March 29</font><font style="display: inline;">, 2016</font><font style="display: inline;"> (the </font><font style="display: inline;">&#x201C;</font><font style="display: inline;">Registration Statement</font><font style="display: inline;">&#x201D;</font><font style="display: inline;">), pursuant to which the </font><font style="display: inline;">Company</font><font style="display: inline;"> registered the resale up to </font><font style="display: inline;">3,703,699 shares of </font><font style="display: inline;">common </font><font style="display: inline;">stock of the Company (the &#x201C;Shares&#x201D;)</font><font style="display: inline;">. The </font><font style="display: inline;">Shares</font><font style="display: inline;"> were registered to permit resale by selling </font><font style="display: inline;">stock</font><font style="display: inline;">holders, as named</font><font style="display: inline;"> in the Registration Statement, who acquired the </font><font style="display: inline;">Shares</font><font style="display: inline;"> in connection with the </font><font style="display: inline;">Company</font><font style="display: inline;">&#x2019;s acquisition</font><font style="display: inline;"> of </font><font style="display: inline;background-color:yellow;">On-X Life Technologies Holdings, Inc.</font>
		</p>
		<p style="margin:0pt 0pt 10pt;border-top:1pt none #D9D9D9 ;text-indent:18pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">The </font><font style="display: inline;">Company</font><font style="display: inline;"> seeks to deregister all </font><font style="display: inline;">of the Shares</font><font style="display: inline;"> that remain unsold under the Registration Statement as of the date hereof because it no longer has an obligation to keep the Registration Statement effective pursuant to the terms of its registration rights agreement with the selli</font><font style="display: inline;">ng </font><font style="display: inline;">stockholders</font><font style="display: inline;">. Accordingly, the </font><font style="display: inline;">Company</font><font style="display: inline;"> is filing this Post-Effective Amendment to terminate the effectiveness of the Registration Statem</font><font style="display: inline;">ent and, in accordance with an undertaking made by the </font><font style="display: inline;">Company</font><font style="display: inline;"> in Part II of the </font><font style="display: inline;">Registration Statement to remove from registration by means of a post-effective amendment</font><font style="display: inline;">&nbsp;</font><font style="display: inline;">any of the securities</font><font style="display: inline;"> registered </font><font style="display: inline;">which remain</font><font style="display: inline;"> unsold </font><font style="display: inline;">at the termination of the offering, remove from registration any and all </font><font style="display: inline;">Shares</font><font style="display: inline;"> registered but unsold </font><font style="display: inline;">under the Registration Statement as of the date hereof. </font>
		</p>
		<p style="margin:0pt 0pt 10pt;font-family:Times New Roman;font-size: 10pt">

		</p>
		<p><font size="1"> </font></p><div style="width:100%">

		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">

			&nbsp;

		</p>

		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">

			&nbsp;

		</p>

		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">

			<font style="font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;font-size:9pt;"></font><font style="display: inline;"></font><font style="display: inline;">3</font><font style="display: inline;"></font>

		</p>

</div><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p>
		<p style="margin:0pt 0pt 10pt;font-family:Times New Roman;;font-size: 10pt"><font style="display: inline;"></font>
		</p>
		<p style="margin:0pt 0pt 10pt;text-align:center;font-weight:bold;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">SIGNATURES </font>
		</p>
		<p style="margin:0pt 0pt 10pt;text-indent:18pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">Pursuant to the requirements of the Securities Act of 1933, as amended, the registrant certifies that it has reasonable grounds to believe that it meets all the requirements for filing on Form S-3 and has duly caused this Post-Effective Amendment to the Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of </font><font style="display: inline;">Kennesaw, </font><font style="display: inline;">State of </font><font style="display: inline;">Georgia</font><font style="display: inline;"> on </font><font style="display: inline;">November 11</font><font style="display: inline;">, 2016. </font>
		</p>
		<p style="margin:0pt 0pt 8pt 216pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">CryoLife, Inc.</font>
		</p>
		<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;margin-bottom:0pt;margin-left:0pt;">
			<tr>
				<td valign="top" style="width:239.40pt;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;height:6.75pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;height:6.75pt;font-size: 1pt">
						<font style="display: inline;font-size:1pt;">&#xFEFF;</font></p>
				</td>
				<td colspan="2" valign="top" style="width:239.40pt;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;height:6.75pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;height:6.75pt;overflow: hidden;font-size:0pt;">
						&nbsp;</p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:239.40pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Date: November 11, 2016</font></p>
				</td>
				<td valign="top" style="width:40.50pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">By:</font></p>
				</td>
				<td valign="top" style="width:198.90pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">/s/ D. Ashley Lee</font></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:239.40pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">&#xFEFF;</font></p>
				</td>
				<td valign="top" style="width:40.50pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Name:</font></p>
				</td>
				<td valign="top" style="width:198.90pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">D. Ashley Lee</font></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:239.40pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">&#xFEFF;</font></p>
				</td>
				<td valign="top" style="width:40.50pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Title:</font></p>
				</td>
				<td valign="top" style="width:198.90pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Executive Vice President, Chief&nbsp;&nbsp;&nbsp;&nbsp;Operating Officer and Chief Financial Officer</font></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:239.40pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">&#xFEFF;</font></p>
				</td>
				<td colspan="2" valign="top" style="width:239.40pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						&nbsp;</p>
				</td>
			</tr>
		</table></div>
		<p style="margin:0pt 0pt 10pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt 0pt 10pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt 0pt 10pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;">&nbsp;</font><font style="display: inline;"></font>
		</p>
		<p style="margin:0pt 0pt 6pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;">POWER OF ATTORNEY </font>
		</p>
		<p style="margin:0pt 0pt 4pt;border-bottom:1pt none #D9D9D9 ;text-indent:18pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">Pursuant to the requirements of the Securities Act of 1933, as amended, this Post-Effective Amendment to the Registration Statement has been signed by the following persons in the capacities and on the dates indicated. </font>
		</p>
		<p style="margin:0pt 0pt 4pt;border-top:1pt none #D9D9D9 ;text-indent:18pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;margin-bottom:0pt;margin-left:0pt;">
			<tr>
				<td valign="top" style="width:159.60pt;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;height:1.00pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;height:1.00pt;overflow:hidden;font-size: 1pt">
						<font style="display: inline;font-size:1pt;">&#xFEFF;</font></p>
				</td>
				<td valign="top" style="width:159.60pt;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;height:1.00pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;height:1.00pt;overflow:hidden;font-size:0pt;">
						&nbsp;</p>
				</td>
				<td valign="top" style="width:159.60pt;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;height:1.00pt;padding:0pt 6.5pt">
					<p style="margin:0pt;font-family:Times New Roman;height:1.00pt;overflow:hidden;font-size:0pt;">
						&nbsp;</p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 3pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-weight:bold;font-size:9pt;">Signature</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 3pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-weight:bold;font-size:9pt;">Title</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 3pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 9pt">
						<font style="display: inline;font-weight:bold;font-size:9pt;">Date</font></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:6pt 0pt 12pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">*</font></p>
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">J. Patrick Mackin</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Chairman of the Board, Chief Executive Officer, President and Director</font><br /><font style="display: inline;">(Principal Executive Officer)</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">November 11, 2016</font></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:6pt 0pt 12pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">&#xFEFF;</font></p>
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">D. Ashley Lee</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Executive Vice President, Chief Operating Officer, Chief Financial Officer and Treasurer</font><br /><font style="display: inline;">(Principal Financial Officer)</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">November 11, 2016</font></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:6pt 0pt 12pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">*</font></p>
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Amy D. Horton</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Vice President, Chief Accounting Officer</font><br /><font style="display: inline;">(Principal Accounting Officer)</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">November 11, 2016</font></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:6pt 0pt 12pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">*</font></p>
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Thomas F. Ackerman</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Director</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">November 11, 2016</font></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:6pt 0pt 12pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">*</font></p>
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">James S. Benson</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Director</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">November 11, 2016</font></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:6pt 0pt 12pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">*</font></p>
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Daniel J. Bevevino</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Director</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">November 11, 2016</font></p>
				</td>
			</tr></table>
		<p><font size="1"> </font></p><div style="width:100%">

		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">

			&nbsp;

		</p>

		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">

			&nbsp;

		</p>

		<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">

			<font style="font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;font-size:9pt;"></font><font style="display: inline;"></font><font style="display: inline;">4</font><font style="display: inline;"></font>

		</p>

</div><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p>
		<table cellpadding="0" cellspacing="0" style="border-collapse:collapse;margin-bottom:0pt;margin-left:0pt;">
			<tr>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:6pt 0pt 12pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">*</font></p>
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Ronald C. Elkins</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Director</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">November 11, 2016</font></p>
				</td>
			</tr>
			<tr>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:6pt 0pt 12pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">*</font></p>
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Ronald D. McCall</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Director</font></p>
				</td>
				<td valign="top" style="width:159.60pt;padding:0pt 6.5pt">
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						<font style="display: inline;">November 11, 2016</font></p>
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						<font style="display: inline;">*</font></p>
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Harvey Morgan</font></p>
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						<font style="display: inline;">Director</font></p>
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					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">November 11, 2016</font></p>
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					<p style="margin:6pt 0pt 12pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">*</font></p>
					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Jon W. Salveson</font></p>
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					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">Director</font></p>
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					<p style="margin:0pt 0pt 12pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;">November 11, 2016</font></p>
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			<font style="display: inline;">&#xFEFF;</font>
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						<font style="display: inline;font-size:10pt;">*By: </font><font style="display: inline;font-size:10pt;text-decoration:underline;">/s/ D. Ashley Lee</font></p>
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					<p style="margin:0pt 0pt 0pt 21.6pt;text-align:left;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-size:10pt;">D. Ashley Lee</font></p>
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						<font style="display: inline;font-size:10pt;">Attorney-in-fact</font></p>
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			<font style="display: inline;">&#xFEFF;</font>
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			&nbsp;

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			&nbsp;

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			<font style="font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;font-size:9pt;"></font><font style="display: inline;"></font><font style="display: inline;">5</font><font style="display: inline;"></font>

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