<SEC-DOCUMENT>0001398344-18-008296.txt : 20180531
<SEC-HEADER>0001398344-18-008296.hdr.sgml : 20180531
<ACCEPTANCE-DATETIME>20180531101015
ACCESSION NUMBER:		0001398344-18-008296
CONFORMED SUBMISSION TYPE:	SD
PUBLIC DOCUMENT COUNT:		2
<RULE>
<RULE-NAME>13p-1
<ITEM>
<ITEM-NUMBER>1.01
<ITEM-PERIOD>20171231
</ITEM>
</RULE>
FILED AS OF DATE:		20180531
DATE AS OF CHANGE:		20180531

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CRYOLIFE INC
		CENTRAL INDEX KEY:			0000784199
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				592417093
		STATE OF INCORPORATION:			FL
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SD
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-13165
		FILM NUMBER:		18870294

	BUSINESS ADDRESS:	
		STREET 1:		1655 ROBERTS BOULEVARD N W
		CITY:			KENNESAW
		STATE:			GA
		ZIP:			30144
		BUSINESS PHONE:		7704193355

	MAIL ADDRESS:	
		STREET 1:		1655 ROBERTS BOULEVARD N W
		CITY:			KENNESAW
		STATE:			GA
		ZIP:			30144
</SEC-HEADER>
<DOCUMENT>
<TYPE>SD
<SEQUENCE>1
<FILENAME>fp0033751_sd.htm
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<P STYLE="font: 14pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>UNITED STATES</B></P>

<P STYLE="font: 14pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><B>WASHINGTON, D.C. 20549</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"></P>

<P STYLE="font: 14pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 11pt"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 14pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>FORM SD</B></P>

<P STYLE="font: 14pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 11pt"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 14pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Specialized Disclosure Report </B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 14pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>CRYOLIFE, INC.</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>(Exact name of registrant as specified in
its charter)</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

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<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>


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    <TD STYLE="vertical-align: top; text-align: center; width: 33%"><FONT STYLE="font-size: 11pt"><B>Florida</B></FONT></TD>
    <TD STYLE="vertical-align: top; text-align: center; width: 34%"><FONT STYLE="font-size: 11pt"><B>1-13165</B></FONT></TD>
    <TD STYLE="vertical-align: top; text-align: center; width: 33%"><FONT STYLE="font-size: 11pt"><B>59-2417093</B></FONT></TD></TR>
<TR>
    <TD STYLE="vertical-align: top">
        <P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>(State or other jurisdiction</B></P>
        <P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>of incorporation)</B></P></TD>
    <TD STYLE="vertical-align: top">
        <P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>(Commission</B></P>
        <P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>File Number)</B></P></TD>
    <TD STYLE="vertical-align: top">
        <P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>(IRS Employer</B></P>
        <P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Identification No.)</B></P></TD></TR>
</TABLE>
<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>1655 Roberts Boulevard, N.W., Kennesaw, Georgia
30144</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>(Address of principal executive office) (zip
code)</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-size: 11pt"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Jean F. Holloway</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Senior Vice President, General Counsel, Corporate
Secretary and Chief Compliance Officer</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>(770) 419-3355</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>(<FONT STYLE="font-family: Times New Roman, Times, Serif">Name
and telephone number, including area code, of person to contact in connection with this report)</FONT></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

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<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">Check the appropriate box to indicate the rule pursuant to which
this form is being filed, and provide the period to which the information in this form applies:</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">__X__ Rule 13p-1 under the Securities Exchange Act (17 CFR 240.13p-1)
for the reporting period from January 1 to December 31, 2017.</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"><B>Section 1 -- Conflict Minerals Disclosure</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"><B>Item 1.01 Conflict Minerals Disclosure and Report</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.25in">This Form SD of CryoLife, Inc. (the <B>&ldquo;Company&rdquo;</B>)
is filed pursuant to Rule 13p-1 promulgated under the Securities Exchange Act of 1934, as amended, for the reporting period January
1, 2017 to December 31, 2017.</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.25in">A copy of the Company&rsquo;s Conflict Minerals
Report is provided as Exhibit 1.01. This Form SD and the Conflict Minerals Report is publicly available on the Company&rsquo;s
website at http://phx.corporate-ir.net/phoenix.zhtml?c=80253&amp;p=irol-confilctminerals.</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"><B>Item 1.01 Exhibit</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.25in">As specified in Section 2, Item 2.01 of this
Form SD, the Company is hereby filing its Conflict Minerals Report as Exhibit 1.01 to this Form SD.</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"><B>Section 2 &ndash; Exhibits</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"><B>Item 2.01 Exhibits</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

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    <TD STYLE="width: 15%; border-bottom: Black 1pt solid"><FONT STYLE="font-size: 11pt"><B>Exhibit No.</B></FONT></TD>
    <TD STYLE="width: 85%; border-bottom: Black 1pt solid"><FONT STYLE="font-size: 11pt"><B>Description</B></FONT></TD></TR>
<TR STYLE="background-color: Gainsboro">
    <TD><FONT STYLE="font-size: 11pt">1.01</FONT></TD>
    <TD><FONT STYLE="font-size: 11pt">Conflict Minerals Report as required by Item 1.01 and 1.02 of this Form</FONT></TD></TR>
</TABLE>
<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>SIGNATURES</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-indent: 23.1pt">Pursuant to the requirements of the Securities
Exchange Act of 1934, CryoLife, Inc. has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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    <TD><FONT STYLE="font-size: 11pt">&nbsp;</FONT></TD>
    <TD COLSPAN="2"><FONT STYLE="font-size: 11pt">CRYOLIFE, INC.</FONT></TD>
    <TD>&nbsp;</TD></TR>
<TR>
    <TD STYLE="width: 50%"><FONT STYLE="font-size: 11pt">&nbsp;</FONT></TD>
    <TD STYLE="width: 5%"><FONT STYLE="font-size: 11pt">&nbsp;</FONT></TD>
    <TD STYLE="width: 35%"><FONT STYLE="font-size: 11pt">&nbsp;</FONT></TD>
    <TD STYLE="width: 10%">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-size: 11pt">Date: May 31, 2018</FONT></TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 11pt">By:</FONT></TD>
    <TD STYLE="vertical-align: bottom">
        <P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; border-bottom: Black 0.75pt solid">/s/ D. Ashley Lee</P></TD>
    <TD>&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-size: 11pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 11pt">Name:</FONT></TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 11pt">D. Ashley Lee</FONT></TD>
    <TD>&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-size: 11pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 11pt">Title:</FONT></TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 11pt">Executive Vice President, Chief</FONT></TD>
    <TD>&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-size: 11pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 11pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 11pt">Operating Officer and Chief</FONT></TD>
    <TD>&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-size: 11pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 11pt">&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 11pt">Financial Officer</FONT></TD>
    <TD>&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>Exhibit
Index</B></FONT></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>&nbsp;</B></FONT></P>

<TABLE CELLSPACING="0" CELLPADDING="4" STYLE="width: 100%; font: 11pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR>
    <TD STYLE="width: 15%; border-bottom: Black 1pt solid"><FONT STYLE="font-size: 11pt"><B>Exhibit No.</B></FONT></TD>
    <TD STYLE="width: 85%; border-bottom: Black 1pt solid"><FONT STYLE="font-size: 11pt"><B>Description</B></FONT></TD></TR>
<TR STYLE="background-color: Gainsboro">
    <TD><FONT STYLE="font-size: 11pt">1.01</FONT></TD>
    <TD><FONT STYLE="font-size: 11pt">Conflict Minerals Report as required by Item 1.01 and 1.02 of this Form</FONT></TD></TR>
</TABLE>
<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"><B>&nbsp;</B></P>

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<DOCUMENT>
<TYPE>EX-1.01
<SEQUENCE>2
<FILENAME>fp0033751_ex101.htm
<DESCRIPTION>CRYOLIFE, INC.
<TEXT>
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<P STYLE="margin: 0"></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: right"><B>Exhibit 1.01</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: right"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>CryoLife, Inc.</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Conflict Minerals Report</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>For the reporting period January 1, 2017
to December 31, 2017</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B><I>Background</I></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B><I>&nbsp;</I></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.25in">This Conflict Minerals
Report (the &ldquo;<B>Report</B>&rdquo;) of CryoLife, Inc. (&ldquo;<B>CryoLife</B>,&rdquo; the &ldquo;<B>Company,</B>&rdquo; &ldquo;<B>we</B>,&rdquo;
or &ldquo;<B>us</B>&rdquo;) has been prepared pursuant to Rule 13p-1 and Form SD (the &ldquo;<B>Rule</B>&rdquo;) promulgated under
the Securities Exchange Act of 1934, as amended, for the reporting period January 1, 2017 to December 31, 2017. The Rule requires
disclosure of certain information when a company manufactures or contracts to manufacture products, and the minerals specified
in the Rule are necessary to the functionality or production of those products. The specified minerals, which we collectively refer
to in this Report as the &ldquo;<B>Conflict Minerals</B>,&rdquo; are gold, columbite-tantalite (coltan), cassiterite, and wolframite
(including their derivatives, which are limited to tantalum, tin, and tungsten). The &ldquo;<B>Covered Countries</B>,&rdquo; for
purposes of the Rule and this Report, are the Democratic Republic of the Congo, the Republic of the Congo, the Central African
Republic, South Sudan, Uganda, Rwanda, Burundi, Tanzania, Zambia, and Angola.</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B><I>Company Overview and Conflict Minerals
Approach</I></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B><I>&nbsp;</I></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.25in">The Company, incorporated
in 1984 in Florida, is a leader in the manufacturing, processing, and distribution of medical devices and implantable human tissues
used in cardiac and vascular surgical procedures focused on aortic repair. Our medical devices and processed tissues primarily
include four product families: BioGlue<SUP>&reg;</SUP> Surgical Adhesive; On-X<SUP>&reg;</SUP> mechanical heart valves and surgical
products; JOTEC<SUP>&reg;</SUP> endovascular and surgical products; and cardiac and vascular human tissues including the CryoValve<SUP>&reg;</SUP>
SG pulmonary heart valve and the CryoPatch<SUP>&reg;</SUP> SG pulmonary cardiac patch, both of which are processed using our proprietary
SynerGraft<SUP>&reg;</SUP> technology. Additional products include CardioGenesis<SUP>&reg;</SUP> cardiac laser therapy, PerClot<SUP>&reg;</SUP>
and PhotoFix<SUP>&reg;</SUP>.</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.25in">Our approach to Conflict
Minerals is based, to the extent applicable and feasible, on the framework set forth in the <I>Organization for Economic Co-operation
and Development Due Diligence Guidance for Responsible Supply Chain of Minerals from Conflict-Affected and High Risk Areas: Third
Edition</I>, including the related supplements on gold, tin, tantalum, and tungsten (the &ldquo;<B>Guidance</B>&rdquo;). As part
of our approach, we maintain a Conflict Minerals Policy (the &ldquo;<B>Policy</B>&rdquo;), which incorporates the standards set
forth in the Guidance. The Policy has been reviewed and approved by senior management and presented to the Audit Committee of the
Company&rsquo;s Board of Directors. In addition, our Purchasing and Legal and Compliance departments have been directed by management
to communicate the Policy to employees who have responsibilities for applying, enforcing, or communicating it internally or to
relevant outside parties. The Policy is maintained on our website.</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B><I>Reasonable Country of Origin Inquiry</I></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B><I>&nbsp;</I></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.25in">Under the Rule, if any
Conflict Minerals are necessary to the functionality or production of a product manufactured by a company or contracted by the
company to be manufactured, the company must conduct, in good faith, a reasonable country of origin inquiry (&ldquo;<B>RCOI</B>&rdquo;)
regarding those Conflict Minerals to determine if the Conflict Minerals originated from a Covered Country or are from recycled
or scrap sources. We undertook a process to identify any necessary Conflict Minerals. Through that process, we determined that
Conflict Minerals from two of our suppliers are necessary and that it is uncertain whether any Conflict Minerals are used by a
third supplier. We subsequently conducted a RCOI to determine whether any of these Conflict Minerals originated from the Covered
Countries or are from recycled or scrap sources. One of our suppliers certified to our reasonable satisfaction that the Conflict
Minerals did not originate in the Covered Countries. One of our suppliers indicated that it obtains Conflict Minerals from a direct
supplier that, in turn, obtains Conflict Minerals from the Covered Countries. One of our suppliers, notwithstanding its due diligence,
was unable to determine whether any Conflict Minerals are used at all because of the large number of upstream suppliers in its
supply chain. As a result, we either know that some of our necessary Conflict Minerals originated from a Covered Country or we
were unable to determine whether the supplier uses Conflict Minerals, which may have originated in the Covered Countries. Accordingly,
the Company undertook the due diligence process described in the section below. Our recently acquired JOTEC products are not covered
by this report.</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B><I>Due Diligence Process and Results</I></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B><I>&nbsp;</I></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.25in">Based on our RCOI, we
exercised reasonable due diligence with respect to the source and chain of custody of the Conflict Minerals that are or might be
contained in our products. As a result of our due diligence, one of our suppliers has provided evidence that the Conflict Minerals
originated from conflict-free sources within the Covered Countries. This supplier obtains the Conflict Minerals directly from Global
Tungsten &amp; Powders Corp., a smelter located in Towanda, Pennsylvania, USA (&ldquo;<B>Global Tungsten</B>&rdquo;). Although
Global Tungsten reportedly obtains Conflict Minerals from Covered Countries, Global Tungsten participates annually in the Responsible
Mineral Initiative (&ldquo;<B>RMI</B>&rdquo;) independent third party audit that examines the purchasing activities, processes,
and systems associated with Global Tungsten&rsquo;s smelting pursuant to the Responsible Minerals Assurance Process (&ldquo;<B>RMAP</B>&rdquo;).
As of the date of this report, Global Tungsten is listed as conformant tungsten smelter by RMI. Our other supplier was unable to
determine whether any Conflict Minerals are used because of the large number of upstream suppliers in its supply chain. We have
continued to engage directly with the supplier&rsquo;s senior management on a number of occasions to determine whether any Conflict
Minerals are used and to obtain information about the upstream supply, the origin of any Conflict Minerals, and whether they benefitted
armed groups in the Covered Countries. For the reporting period, however, the supplier was unable to confirm precisely whether
any Conflict Minerals are used or to conclusively determine the country of origin of those minerals.</P>

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<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.25in">There are many third parties
in the supply chain between our direct suppliers and the original sources of any actual or potential Conflict Minerals. In this
regard, we do not purchase Conflict Minerals directly from mines, smelters, or refiners. We must therefore rely on our suppliers
and their upstream supplier to provide information regarding the origin of any Conflict Minerals.</P>

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<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.25in">This Conflict Minerals
Report is unaudited.</P>

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<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B><I>Risk Mitigation</I></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><B><I>&nbsp;</I></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify; text-indent: 0.25in">We intend to take the
following steps to mitigate the risk that our necessary Conflict Minerals benefit armed groups:</P>

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<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 11pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: justify; width: 2%">&bull;</TD>
    <TD STYLE="text-align: justify; width: 98%"><P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 11pt">We will continue to work with our supplier who provided incomplete information to obtain complete and accurate information for 2018;</FONT></P>
                                                <P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 11pt">&nbsp;</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: justify">&bull;</TD>
    <TD STYLE="text-align: justify"><P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 11pt">We will continue to follow our due diligence process and make improvements in our due diligence process as warranted; and</FONT></P>
                                    <P STYLE="margin-top: 0; margin-bottom: 0"><FONT STYLE="font-size: 11pt">&nbsp;</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: justify">&bull;</TD>
    <TD STYLE="text-align: justify"><FONT STYLE="font-size: 11pt">We will continue to inform our suppliers about the principles set forth in our Policy.</FONT></TD></TR>
</TABLE>
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<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"><B><I>Forward-Looking Statements</I></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0"><B><I>&nbsp;</I></B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><I>Statements made in this Report that look
forward in time or that express management's beliefs, expectations, or hopes are forward-looking statements within the meaning
of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements reflect the views of management at the
time such statements are made. These statements include those regarding the steps the Company expects to take to improve its due
diligence measures and further mitigate the risk that necessary Conflict Minerals contained in the Company&rsquo;s products finance
or benefit armed groups in the Covered Countries. These forward-looking statements are subject to a number of risks, uncertainties,
estimates, and assumptions that may cause actual results to differ materially from current expectations. These risks and uncertainties
include, but are not limited to, internal and external resource constraints,, the continued implementation of satisfactory traceability
and other compliance measures by our direct and indirect suppliers on a timely basis or at all, whether smelters, refiners and
other market participants responsibly source Conflict Minerals, and political and regulatory developments, whether in the Covered
Countries, the United States or elsewhere. These risks and uncertainties include the risk factors detailed in our Securities and
Exchange Commission filings, including our Form 10-K for the year ended December 31, 2017, and our subsequent filings with the
SEC. CryoLife does not undertake to update its forward-looking statements.</I></P>

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<P STYLE="font: 11pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; text-align: center"><FONT STYLE="font-size: 9pt">E-2</FONT></P>

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