<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2022 Workiva-->
<!--r:e6891988-c797-4972-93bc-9ac5fa18c933,g:19ec5362-98a4-465a-8335-497bfcde1bb2-->
<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:aort="http://www.cryolife.com/20220930" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:dtr-types="http://www.xbrl.org/dtr/type/2020-01-21" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" attributeFormDefault="unqualified" elementFormDefault="qualified" targetNamespace="http://www.cryolife.com/20220930">
  <xs:import namespace="http://fasb.org/srt/2021-01-31" schemaLocation="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd"/>
  <xs:import namespace="http://fasb.org/us-gaap/2021-01-31" schemaLocation="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd"/>
  <xs:import namespace="http://www.w3.org/1999/xlink" schemaLocation="http://www.xbrl.org/2003/xlink-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/2003/instance" schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/2003/linkbase" schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/dtr/type/2020-01-21" schemaLocation="https://www.xbrl.org/dtr/type/2020-01-21/types.xsd"/>
  <xs:import namespace="http://xbrl.org/2005/xbrldt" schemaLocation="http://www.xbrl.org/2005/xbrldt-2005.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/country/2021" schemaLocation="https://xbrl.sec.gov/country/2021/country-2021.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/dei/2021q4" schemaLocation="https://xbrl.sec.gov/dei/2021q4/dei-2021q4.xsd"/>
  <xs:annotation>
    <xs:appinfo>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="aort-20220930_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="aort-20220930_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="aort-20220930_cal.xml" xlink:role="http://www.xbrl.org/2003/role/calculationLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="aort-20220930_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:type="simple"/>
      <link:roleType id="Cover" roleURI="http://www.cryolife.com/role/Cover">
        <link:definition>0000001 - Document - Cover</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CondensedConsolidatedStatementsofOperationsandComprehensiveLossIncome" roleURI="http://www.cryolife.com/role/CondensedConsolidatedStatementsofOperationsandComprehensiveLossIncome">
        <link:definition>0000002 - Statement - Condensed Consolidated Statements of Operations and Comprehensive (Loss) Income</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CondensedConsolidatedBalanceSheets" roleURI="http://www.cryolife.com/role/CondensedConsolidatedBalanceSheets">
        <link:definition>0000003 - Statement - Condensed Consolidated Balance Sheets</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CondensedConsolidatedBalanceSheetsParenthetical" roleURI="http://www.cryolife.com/role/CondensedConsolidatedBalanceSheetsParenthetical">
        <link:definition>0000004 - Statement - Condensed Consolidated Balance Sheets (Parenthetical)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CondensedConsolidatedStatementsofCashFlows" roleURI="http://www.cryolife.com/role/CondensedConsolidatedStatementsofCashFlows">
        <link:definition>0000005 - Statement - Condensed Consolidated Statements of Cash Flows</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CondensedConsolidatedStatementsofShareholdersEquity" roleURI="http://www.cryolife.com/role/CondensedConsolidatedStatementsofShareholdersEquity">
        <link:definition>0000006 - Statement - Condensed Consolidated Statements of Shareholders' Equity</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BasisofPresentationandSummaryofSignificantAccountingPolicies" roleURI="http://www.cryolife.com/role/BasisofPresentationandSummaryofSignificantAccountingPolicies">
        <link:definition>0000007 - Disclosure - Basis of Presentation and Summary of Significant Accounting Policies</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SaleofPerClot" roleURI="http://www.cryolife.com/role/SaleofPerClot">
        <link:definition>0000008 - Disclosure - Sale of PerClot</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancialInstruments" roleURI="http://www.cryolife.com/role/FinancialInstruments">
        <link:definition>0000009 - Disclosure - Financial Instruments</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CashEquivalents" roleURI="http://www.cryolife.com/role/CashEquivalents">
        <link:definition>0000010 - Disclosure - Cash Equivalents</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InventoriesnetandDeferredPreservationCosts" roleURI="http://www.cryolife.com/role/InventoriesnetandDeferredPreservationCosts">
        <link:definition>0000011 - Disclosure - Inventories, net and Deferred Preservation Costs</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandOtherIntangibleAssets" roleURI="http://www.cryolife.com/role/GoodwillandOtherIntangibleAssets">
        <link:definition>0000012 - Disclosure - Goodwill and Other Intangible Assets</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxes" roleURI="http://www.cryolife.com/role/IncomeTaxes">
        <link:definition>0000013 - Disclosure - Income Taxes</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Leases" roleURI="http://www.cryolife.com/role/Leases">
        <link:definition>0000014 - Disclosure - Leases</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Debt" roleURI="http://www.cryolife.com/role/Debt">
        <link:definition>0000015 - Disclosure - Debt</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CommitmentsandContingencies" roleURI="http://www.cryolife.com/role/CommitmentsandContingencies">
        <link:definition>0000016 - Disclosure - Commitments and Contingencies</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenueRecognition" roleURI="http://www.cryolife.com/role/RevenueRecognition">
        <link:definition>0000017 - Disclosure - Revenue Recognition</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockCompensation" roleURI="http://www.cryolife.com/role/StockCompensation">
        <link:definition>0000018 - Disclosure - Stock Compensation</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LossEarningsPerCommonShare" roleURI="http://www.cryolife.com/role/LossEarningsPerCommonShare">
        <link:definition>0000019 - Disclosure - (Loss) Earnings Per Common Share</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentInformation" roleURI="http://www.cryolife.com/role/SegmentInformation">
        <link:definition>0000020 - Disclosure - Segment Information</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BasisofPresentationandSummaryofSignificantAccountingPoliciesPolicies" roleURI="http://www.cryolife.com/role/BasisofPresentationandSummaryofSignificantAccountingPoliciesPolicies">
        <link:definition>0000021 - Disclosure - Basis of Presentation and Summary of Significant Accounting Policies (Policies)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancialInstrumentsTables" roleURI="http://www.cryolife.com/role/FinancialInstrumentsTables">
        <link:definition>0000022 - Disclosure - Financial Instruments (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CashEquivalentsTables" roleURI="http://www.cryolife.com/role/CashEquivalentsTables">
        <link:definition>0000023 - Disclosure - Cash Equivalents (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InventoriesNetAndDeferredPreservationCostsTables" roleURI="http://www.cryolife.com/role/InventoriesNetAndDeferredPreservationCostsTables">
        <link:definition>0000024 - Disclosure - Inventories, Net And Deferred Preservation Costs (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandOtherIntangibleAssetsTables" roleURI="http://www.cryolife.com/role/GoodwillandOtherIntangibleAssetsTables">
        <link:definition>0000025 - Disclosure - Goodwill and Other Intangible Assets (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesTables" roleURI="http://www.cryolife.com/role/LeasesTables">
        <link:definition>0000026 - Disclosure - Leases (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DebtTables" roleURI="http://www.cryolife.com/role/DebtTables">
        <link:definition>0000027 - Disclosure - Debt (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenueRecognitionTables" roleURI="http://www.cryolife.com/role/RevenueRecognitionTables">
        <link:definition>0000028 - Disclosure - Revenue Recognition (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockCompensationTables" roleURI="http://www.cryolife.com/role/StockCompensationTables">
        <link:definition>0000029 - Disclosure - Stock Compensation (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LossEarningsPerCommonShareTables" roleURI="http://www.cryolife.com/role/LossEarningsPerCommonShareTables">
        <link:definition>0000030 - Disclosure - (Loss) Earnings Per Common Share (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentInformationTables" roleURI="http://www.cryolife.com/role/SegmentInformationTables">
        <link:definition>0000031 - Disclosure - Segment Information (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SaleofPerClotDetails" roleURI="http://www.cryolife.com/role/SaleofPerClotDetails">
        <link:definition>0000032 - Disclosure - Sale of PerClot (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancialInstrumentsSummaryOfFinancialInstrumentsMeasuredAtFairValueDetails" roleURI="http://www.cryolife.com/role/FinancialInstrumentsSummaryOfFinancialInstrumentsMeasuredAtFairValueDetails">
        <link:definition>0000033 - Disclosure - Financial Instruments (Summary Of Financial Instruments Measured At Fair Value) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancialInstrumentsNarrativeDetails" roleURI="http://www.cryolife.com/role/FinancialInstrumentsNarrativeDetails">
        <link:definition>0000034 - Disclosure - Financial Instruments (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancialInstrumentsReconciliationOfChangesInFairValueOfLevel3LiabilitiesDetails" roleURI="http://www.cryolife.com/role/FinancialInstrumentsReconciliationOfChangesInFairValueOfLevel3LiabilitiesDetails">
        <link:definition>0000035 - Disclosure - Financial Instruments (Reconciliation Of Changes In Fair Value Of Level 3 Liabilities) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CashEquivalentsSummaryOfCashEquivalentsAndRestrictedSecuritiesDetails" roleURI="http://www.cryolife.com/role/CashEquivalentsSummaryOfCashEquivalentsAndRestrictedSecuritiesDetails">
        <link:definition>0000036 - Disclosure - Cash Equivalents (Summary Of Cash Equivalents And Restricted Securities) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CashEquivalentsNarrativeDetails" roleURI="http://www.cryolife.com/role/CashEquivalentsNarrativeDetails">
        <link:definition>0000037 - Disclosure - Cash Equivalents (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InventoriesnetandDeferredPreservationCostsScheduleOfInventoriesDetails" roleURI="http://www.cryolife.com/role/InventoriesnetandDeferredPreservationCostsScheduleOfInventoriesDetails">
        <link:definition>0000038 - Disclosure - Inventories, net and Deferred Preservation Costs (Schedule Of Inventories) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InventoriesnetandDeferredPreservationCostsNarrativeDetails" roleURI="http://www.cryolife.com/role/InventoriesnetandDeferredPreservationCostsNarrativeDetails">
        <link:definition>0000039 - Disclosure - Inventories, net and Deferred Preservation Costs (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandOtherIntangibleAssetsScheduleofCarryingValuesofIndefiniteLivedIntangibleAssetsDetails" roleURI="http://www.cryolife.com/role/GoodwillandOtherIntangibleAssetsScheduleofCarryingValuesofIndefiniteLivedIntangibleAssetsDetails">
        <link:definition>0000040 - Disclosure - Goodwill and Other Intangible Assets (Schedule of Carrying Values of Indefinite Lived Intangible Assets) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandOtherIntangibleAssetsScheduleofGoodwillbyReportableSegmentDetails" roleURI="http://www.cryolife.com/role/GoodwillandOtherIntangibleAssetsScheduleofGoodwillbyReportableSegmentDetails">
        <link:definition>0000041 - Disclosure - Goodwill and Other Intangible Assets (Schedule of Goodwill by Reportable Segment) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandOtherIntangibleAssetsScheduleofGrossCarryingValuesAccumulatedAmortizationandApproximateAmortizationPeriodofDefiniteLivedIntangibleAssetsDetails" roleURI="http://www.cryolife.com/role/GoodwillandOtherIntangibleAssetsScheduleofGrossCarryingValuesAccumulatedAmortizationandApproximateAmortizationPeriodofDefiniteLivedIntangibleAssetsDetails">
        <link:definition>0000042 - Disclosure - Goodwill and Other Intangible Assets (Schedule of Gross Carrying Values, Accumulated Amortization, and Approximate Amortization Period of Definite Lived Intangible Assets) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandOtherIntangibleAssetsSummaryofAmortizationExpenseDetails" roleURI="http://www.cryolife.com/role/GoodwillandOtherIntangibleAssetsSummaryofAmortizationExpenseDetails">
        <link:definition>0000043 - Disclosure - Goodwill and Other Intangible Assets (Summary of Amortization Expense) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandOtherIntangibleAssetsScheduledAmortizationofIntangibleAssetsforNextFiveYearsDetails" roleURI="http://www.cryolife.com/role/GoodwillandOtherIntangibleAssetsScheduledAmortizationofIntangibleAssetsforNextFiveYearsDetails">
        <link:definition>0000044 - Disclosure - Goodwill and Other Intangible Assets (Scheduled Amortization of Intangible Assets for Next Five Years) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxesDetails" roleURI="http://www.cryolife.com/role/IncomeTaxesDetails">
        <link:definition>0000045 - Disclosure - Income Taxes (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesNarrativeDetails" roleURI="http://www.cryolife.com/role/LeasesNarrativeDetails">
        <link:definition>0000046 - Disclosure - Leases (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesScheduleOfSupplementalBalanceSheetInformationRelatedToLeasesDetails" roleURI="http://www.cryolife.com/role/LeasesScheduleOfSupplementalBalanceSheetInformationRelatedToLeasesDetails">
        <link:definition>0000047 - Disclosure - Leases (Schedule Of Supplemental Balance Sheet Information Related To Leases) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesSummaryOfLeaseCostsDetails" roleURI="http://www.cryolife.com/role/LeasesSummaryOfLeaseCostsDetails">
        <link:definition>0000048 - Disclosure - Leases (Summary Of Lease Costs) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesScheduleOfSupplementalCashFlowInformationRelatedToLeasesDetails" roleURI="http://www.cryolife.com/role/LeasesScheduleOfSupplementalCashFlowInformationRelatedToLeasesDetails">
        <link:definition>0000049 - Disclosure - Leases (Schedule Of Supplemental Cash Flow Information Related To Leases) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesScheduleOfMinimumLeasePaymentsForFinanceOperatingAndSubleaseIncomeLeasesDetails" roleURI="http://www.cryolife.com/role/LeasesScheduleOfMinimumLeasePaymentsForFinanceOperatingAndSubleaseIncomeLeasesDetails">
        <link:definition>0000050 - Disclosure - Leases (Schedule Of Minimum Lease Payments For Finance, Operating, And Sublease Income Leases) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DebtNarrativeDetails" roleURI="http://www.cryolife.com/role/DebtNarrativeDetails">
        <link:definition>0000051 - Disclosure - Debt (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DebtScheduleOfShortTermAndLongTermBalancesOfTermLoanDetails" roleURI="http://www.cryolife.com/role/DebtScheduleOfShortTermAndLongTermBalancesOfTermLoanDetails">
        <link:definition>0000052 - Disclosure - Debt (Schedule Of Short-Term And Long-Term Balances Of Term Loan) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CommitmentsandContingenciesDetails" roleURI="http://www.cryolife.com/role/CommitmentsandContingenciesDetails">
        <link:definition>0000053 - Disclosure - Commitments and Contingencies (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenueRecognitionDisaggregationOfRevenueDetails" roleURI="http://www.cryolife.com/role/RevenueRecognitionDisaggregationOfRevenueDetails">
        <link:definition>0000054 - Disclosure - Revenue Recognition (Disaggregation Of Revenue) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockCompensationNarrativeDetails" roleURI="http://www.cryolife.com/role/StockCompensationNarrativeDetails">
        <link:definition>0000055 - Disclosure - Stock Compensation (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockCompensationScheduleOfWeightedAverageAssumptionsUsedToDetermineTheFairValueOfOptionsDetails" roleURI="http://www.cryolife.com/role/StockCompensationScheduleOfWeightedAverageAssumptionsUsedToDetermineTheFairValueOfOptionsDetails">
        <link:definition>0000056 - Disclosure - Stock Compensation (Schedule Of Weighted-Average Assumptions Used To Determine The Fair Value Of Options) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockCompensationSummaryOfTotalStockCompensationExpensesDetails" roleURI="http://www.cryolife.com/role/StockCompensationSummaryOfTotalStockCompensationExpensesDetails">
        <link:definition>0000057 - Disclosure - Stock Compensation (Summary Of Total Stock Compensation Expenses) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LossEarningsPerCommonShareComputationOfBasicAndDilutedLossIncomePerCommonShareDetails" roleURI="http://www.cryolife.com/role/LossEarningsPerCommonShareComputationOfBasicAndDilutedLossIncomePerCommonShareDetails">
        <link:definition>0000058 - Disclosure - (Loss) Earnings Per Common Share (Computation Of Basic And Diluted (Loss) Income Per Common Share) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentInformationNarrativeDetails" roleURI="http://www.cryolife.com/role/SegmentInformationNarrativeDetails">
        <link:definition>0000059 - Disclosure - Segment Information (Narrative) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentInformationRevenuesCostOfProductsAndServicesAndGrossMarginsForOperatingSegmentsDetails" roleURI="http://www.cryolife.com/role/SegmentInformationRevenuesCostOfProductsAndServicesAndGrossMarginsForOperatingSegmentsDetails">
        <link:definition>0000060 - Disclosure - Segment Information (Revenues, Cost Of Products And Services, And Gross Margins For Operating Segments) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentInformationSummaryOfNetRevenuesByProductAndServiceDetails" roleURI="http://www.cryolife.com/role/SegmentInformationSummaryOfNetRevenuesByProductAndServiceDetails">
        <link:definition>0000061 - Disclosure - Segment Information (Summary Of Net Revenues By Product And Service) (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
    </xs:appinfo>
  </xs:annotation>
  <xs:element id="aort_StarchMedicalInc.Member" abstract="false" name="StarchMedicalInc.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_AscyrusMedicalLlcMember" abstract="false" name="AscyrusMedicalLlcMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentalsYearTwo" abstract="false" name="OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentalsYearTwo" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_InternationalDistributorMember" abstract="false" name="InternationalDistributorMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_MedicalDevicesMember" abstract="false" name="MedicalDevicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_StockOptionAndEmployeeStockPurchasePlanOptionExpenseMember" abstract="false" name="StockOptionAndEmployeeStockPurchasePlanOptionExpenseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_DebtInstrumentConvertibleRedemptionPercentageOfPrincipalAmount" abstract="false" name="DebtInstrumentConvertibleRedemptionPercentageOfPrincipalAmount" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="aort_OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentalsYearFour" abstract="false" name="OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentalsYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_CircumstanceAfterJuly52023Member" abstract="false" name="CircumstanceAfterJuly52023Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_ProductsMember" abstract="false" name="ProductsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_DomesticHospitalsMember" abstract="false" name="DomesticHospitalsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentalsRemainderOfFiscalYear" abstract="false" name="OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentalsRemainderOfFiscalYear" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_DebtInstrumentExtensionPeriod" abstract="false" name="DebtInstrumentExtensionPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="aort_ShareBasedCompensationArrangementByShareBasedPaymentAwardOtherThanOptionsMarketValueOfSharesGranted" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOtherThanOptionsMarketValueOfSharesGranted" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_GovernmentSponsoredDebtKfwLoan1Member" abstract="false" name="GovernmentSponsoredDebtKfwLoan1Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_FinanceLeaseCost" abstract="false" name="FinanceLeaseCost" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_PropertyPlantAndEquipmentAndOperatingLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization" abstract="false" name="PropertyPlantAndEquipmentAndOperatingLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_DisposalGroupIncludingDiscontinuedOperationContingentConsiderationReceivable" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationContingentConsiderationReceivable" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentalsYearThree" abstract="false" name="OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentalsYearThree" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_ConsignmentInventoryPercentage" abstract="false" name="ConsignmentInventoryPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="aort_AssetsAndLiabilitiesLesseeTableTextBlock" abstract="false" name="AssetsAndLiabilitiesLesseeTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="aort_DebtPeriodAxis" abstract="true" name="DebtPeriodAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="aort_BaxterAchievementOfWorldwideSalesMember" abstract="false" name="BaxterAchievementOfWorldwideSalesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentalsAfterYearFour" abstract="false" name="OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentalsAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_DebtPeriodDomain" abstract="true" name="DebtPeriodDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_ContingentConsiderationNoncurrentFairValue" abstract="false" name="ContingentConsiderationNoncurrentFairValue" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_PropertyPlantAndEquipmentAndOperatingLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization" abstract="false" name="PropertyPlantAndEquipmentAndOperatingLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_RestrictedStockAwardsRestrictedStockUnitsPerformanceStockAwardsPerformanceStockUnitsMember" abstract="false" name="RestrictedStockAwardsRestrictedStockUnitsPerformanceStockAwardsPerformanceStockUnitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_AorticStentGraftsMember" abstract="false" name="AorticStentGraftsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_CardiogenesisMember" abstract="false" name="CardiogenesisMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_PmaApprovalMember" abstract="false" name="PmaApprovalMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_NoncashInterestExpense" abstract="false" name="NoncashInterestExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_RevolvingCreditFacilityAndTermLoanMember" abstract="false" name="RevolvingCreditFacilityAndTermLoanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_PerClotMember" abstract="false" name="PerClotMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_DebtInstrumentExtensionCircumstancePeriod" abstract="false" name="DebtInstrumentExtensionCircumstancePeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="aort_FiniteLivedIntangibleAssetsAmortizationExpenseEstimate" abstract="false" name="FiniteLivedIntangibleAssetsAmortizationExpenseEstimate" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_DeferredPreservationCosts" abstract="false" name="DeferredPreservationCosts" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_WriteDownOfDeferredPreservationCostsAndInventories" abstract="false" name="WriteDownOfDeferredPreservationCostsAndInventories" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_RevolvingCreditFacilityPercentageRepaidForNoCovenants" abstract="false" name="RevolvingCreditFacilityPercentageRepaidForNoCovenants" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="aort_IncreaseDecreaseInDeferredPreservationCostsAndInventories" abstract="false" name="IncreaseDecreaseInDeferredPreservationCostsAndInventories" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_CircumstanceIiMember" abstract="false" name="CircumstanceIiMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_FinanceLeaseLiabilityToBePaidAfterYearFour" abstract="false" name="FinanceLeaseLiabilityToBePaidAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_NoncashLeaseExpense" abstract="false" name="NoncashLeaseExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_ArtivionInc.AndStarchMedicalInc.Member" abstract="false" name="ArtivionInc.AndStarchMedicalInc.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_OnXMember" abstract="false" name="OnXMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentalsYearOne" abstract="false" name="OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentalsYearOne" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_PreservationServicesMember" abstract="false" name="PreservationServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_CircumstanceIMember" abstract="false" name="CircumstanceIMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_CreditAgreementMember" abstract="true" name="CreditAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_TransferOfPerclotManufacturingEquipmentMember" abstract="false" name="TransferOfPerclotManufacturingEquipmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_AccruedProcurementFees" abstract="false" name="AccruedProcurementFees" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_InternationalHospitalsMember" abstract="false" name="InternationalHospitalsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_GovernmentSponsoredDebtKfwLoan2Member" abstract="false" name="GovernmentSponsoredDebtKfwLoan2Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" abstract="false" name="LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_ResearchAndDevelopmentExpenseTerminationAndWindDownCosts" abstract="false" name="ResearchAndDevelopmentExpenseTerminationAndWindDownCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="aort_OtherProductsMember" abstract="false" name="OtherProductsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_RestrictedStockAwardsRestrictedStockUnitsPreferredStockUnitsMember" abstract="false" name="RestrictedStockAwardsRestrictedStockUnitsPreferredStockUnitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_IntangibleAssetsOtherThanAcquiredTechnologyMember" abstract="false" name="IntangibleAssetsOtherThanAcquiredTechnologyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="aort_SurgicalSealantsMember" abstract="false" name="SurgicalSealantsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
