<SEC-DOCUMENT>0001831942-25-000029.txt : 20251114
<SEC-HEADER>0001831942-25-000029.hdr.sgml : 20251114
<ACCEPTANCE-DATETIME>20251114165749
ACCESSION NUMBER:		0001831942-25-000029
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20251114
DATE AS OF CHANGE:		20251114

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Cogent Biosciences, Inc.
		CENTRAL INDEX KEY:			0001622229
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				465308248
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-90431
		FILM NUMBER:		251487832

	BUSINESS ADDRESS:	
		STREET 1:		275 WYMAN STREET
		STREET 2:		3RD FLOOR
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451
		BUSINESS PHONE:		617-945-5576

	MAIL ADDRESS:	
		STREET 1:		275 WYMAN STREET
		STREET 2:		3RD FLOOR
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Unum Therapeutics Inc.
		DATE OF NAME CHANGE:	20180402

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Unum Therapeutics, Inc.
		DATE OF NAME CHANGE:	20141014

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Commodore Capital LP
		CENTRAL INDEX KEY:			0001831942
		ORGANIZATION NAME:           	
		EIN:				832659606
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		444 MADISON AVENUE
		STREET 2:		35TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		212-256-8600

	MAIL ADDRESS:	
		STREET 1:		444 MADISON AVENUE
		STREET 2:		35TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	COMMODORE CAPITAL LP
		DATE OF NAME CHANGE:	20201110
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      <amendmentNo>1</amendmentNo>
      <securitiesClassTitle>Common Stock, $0.001 Par Value</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>09/30/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001622229</issuerCik>
        <issuerName>Cogent Biosciences, Inc.</issuerName>
        <issuerCusip>19240Q201</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>275 Wyman Street</com:street1>
          <com:street2>3rd Floor</com:street2>
          <com:city>Waltham</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02451</com:zipCode>
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      <reportingPersonName>Commodore Capital LP</reportingPersonName>
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      <typeOfReportingPerson>PN</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Commodore Capital Master LP</reportingPersonName>
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    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Robert Egen Atkinson</reportingPersonName>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
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      <classPercent>7.2</classPercent>
      <typeOfReportingPerson>HC</typeOfReportingPerson>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Michael Kramarz</reportingPersonName>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
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        <sharedDispositivePower>10208060.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>10208060.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>7.2</classPercent>
      <typeOfReportingPerson>HC</typeOfReportingPerson>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
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    <items>
      <item1>
        <issuerName>Cogent Biosciences, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>275 Wyman Street, 3rd Floor, Waltham, MASSACHUSETTS, 02451.</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Commodore Capital LP
Commodore Capital Master LP
Robert Egen Atkinson
Michael Kramarz

Each a "Filer."</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>The address for Commodore Capital LP, Robert Egen Atkinson, and Michael Kramarz is 444 Madison
Avenue, Floor 35, New York, NY 10022.

The address for Commodore Capital Master LP is c/o Maples Corporate Services Limited, Ugland
House, South Church Street, PO Box 309, Grand Cayman KY1-1104, Cayman Islands.</principalBusinessOfficeOrResidenceAddress>
        <citizenship>See Item 4 of the cover page for each Filer.</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>See Item 9 of the cover page for each Filer.

This report on Schedule 13G is being filed by Commodore Capital LP (the "Firm"), Commodore Capital Master LP ("Commodore Master"), Michael Kramarz, and Robert Egen Atkinson. The Firm is the investment manager to Commodore Master. As of September 30, 2025, the Firm may be deemed to beneficially own an aggregate of 10,208,060 shares Common Stock, $0.001 Par Value per share (the "Common Stock"), of Cogent Biosciences, Inc. (the "Issuer"), consisting of (i) 7,250,000 shares of Common Stock (ii) 2,352,000 shares of Common Stock underlying Series B Non-Voting Convertible Preferred Stock, which is subject to a beneficial ownership limitation of 9.99%, and (iii) 606,060 shares of Common Stock underlying a warrant which is subject to a beneficial ownership limitation of 9.99%. The Firm, as the investment manager to Commodore Master, may be deemed to beneficially own these securities. Michael Kramarz and Robert Egen Atkinson are the managing partners of the Firm and exercise investment discretion with respect to these securities. Ownership percentages are based on 139,827,662 Common Shares reported as issued and outstanding as of September 30, 2025 in the Issuer's Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 7, 2025, plus 2,352,000 shares of Common Stock underlying Series B Non-Voting Convertible Preferred Stock and 606,060 shares of Common Stock which the Filers may acquire upon the exercise of the warrants, subject to the beneficial ownership limitation of 9.99%.</amountBeneficiallyOwned>
        <classPercent>See Item 11 of the cover page for each Filer.</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>See Item 5 of the cover page for each Filer.</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>See Item 6 of the cover page for each Filer.</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>See Item 7 of the cover page for each Filer.</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>See Item 8 of the cover page for each Filer.</sharedPowerOrDirectToDispose>
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        <notApplicableFlag>Y</notApplicableFlag>
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      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
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      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under &amp;#167; 240.14a-11.

</certifications>
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    </items>
    <exhibitInfo>Exhibit 1: Joint Filing Agreement</exhibitInfo>
    <signatureInformation>
      <reportingPersonName>Commodore Capital LP</reportingPersonName>
      <signatureDetails>
        <signature>Michael Kramarz</signature>
        <title>Managing Partner</title>
        <date>11/14/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Commodore Capital Master LP</reportingPersonName>
      <signatureDetails>
        <signature>Michael Kramarz</signature>
        <title>Authorized Signatory</title>
        <date>11/14/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Robert Egen Atkinson</reportingPersonName>
      <signatureDetails>
        <signature>Robert Egen Atkinson</signature>
        <title>Authorized Signatory</title>
        <date>11/14/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Michael Kramarz</reportingPersonName>
      <signatureDetails>
        <signature>Michael Kramarz</signature>
        <title>Authorized Signatory</title>
        <date>11/14/2025</date>
      </signatureDetails>
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<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: right">Exhibit 1</P>

<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><B>JOINT FILING AGREEMENT</B></P>

<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0">The undersigned acknowledge and agree that the foregoing statement on Schedule
13G is filed on behalf of each of the undersigned, and that all subsequent amendments to this statement on Schedule 13G shall be filed
on behalf of each of the undersigned without the necessity of filing additional joint acquisition statements. The undersigned acknowledge
that each shall be responsible for the timely filing of such amendments, and for the completeness and accuracy of the information concerning
it contained therein, but shall not be responsible for the completeness and accuracy of the information concerning the other, except to
the extent that it knows or has reason to believe that such information is inaccurate.</P>

<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0">Dated: November 14, 2025</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">By: <B>Commodore Capital LP</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">By: <U>/s/Michael Kramarz</U></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">Name: Michael Kramarz</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">Title: Managing Partner</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">By: <B>Commodore Capital Master LP</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">By: <U>/s/Michael Kramarz </U></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">Name: Michael Kramarz</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">By: <B>Robert Egen Atkinson</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">By: <U>/s/Robert Egen Atkinson</U></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">Name: Robert Egen Atkinson</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">By: <B>Michael Kramarz</B></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">By: <U>/s/ Michael Kramarz </U></P>

<P STYLE="font: 11pt Times New Roman, Times, Serif; margin: 0 0 0 3.5in">Name: Michael Kramarz</P>

<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 12pt Times New Roman, Times, Serif; margin: 0 0 0 4in">&nbsp;</P>

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