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Consolidated Statements of Stockholders' Equity (Deficit) - USD ($)
shares in Thousands, $ in Thousands
Total
Series A-2 Convertible Preferred Stock
Convertible Preferred Stock
Convertible Preferred Stock
Series A-2 Convertible Preferred Stock
Common Stock
Additional Paid-in Capital
Accumulated Deficit
Beginning balance, shares at Dec. 31, 2013     122,216   5,494    
Beginning balance at Dec. 31, 2013 $ (2,968)   $ 53,734   $ 5 $ 34,089 $ (90,796)
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
New issuances, shares       166 11,500    
New issuances 70,626 $ 509   $ 509 $ 11 70,615  
Conversion of preferred stock to common stock upon IPO, shares     (122,382)   30,595    
Conversion of preferred stock to common stock upon IPO (54,243)   $ (54,243)   $ 31 54,212  
Reclass of warrant liabilities to APIC upon IPO 2,647         2,647  
Issuance of common stock upon exercise of stock options and warrants, shares         1,556    
Issuance of common stock upon exercise of stock options and warrants 1,112       $ 2 1,110  
Issuance of common stock upon vesting of restricted stock units, shares         15    
Issuance of common stock under ESPP, shares         156    
Issuance of common stock under ESPP 660         660  
Issuance of unregistered common stock         6    
Vesting of early exercised stock options 200         200  
Stock-based compensation 6,753         6,753  
Net loss (37,786)           (37,786)
Ending balance at Dec. 31, 2014 41,753   $ 0   $ 49 170,286 (128,582)
Ending balance, shares at Dec. 31, 2014     0   49,322    
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Conversion of preferred stock to common stock upon IPO 0            
Reclass of warrant liabilities to APIC upon IPO 0            
Issuance of common stock upon exercise of stock options and warrants, shares         992    
Issuance of common stock upon exercise of stock options and warrants 1,266       $ 1 1,265  
Issuance of common stock upon vesting of restricted stock units, shares         566    
Issuance of common stock upon vesting of restricted stock units 0       $ 1 (1)  
Issuance of common stock under ESPP, shares         306    
Issuance of common stock under ESPP 1,369         1,369  
Vesting of early exercised stock options 0            
Stock-based compensation 7,730         7,730  
Forfeiture of unvested restricted common stock, shares         (21)    
Forfeiture of unvested restricted common stock 0            
Net loss (25,838)           (25,838)
Ending balance at Dec. 31, 2015 26,280   $ 0   $ 51 180,649 (154,420)
Ending balance, shares at Dec. 31, 2015     0   51,165    
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Conversion of preferred stock to common stock upon IPO 0            
Reclass of warrant liabilities to APIC upon IPO 0            
Issuance of common stock upon exercise of stock options and warrants, shares         982    
Issuance of common stock upon exercise of stock options and warrants 4,286       $ 1 4,285  
Issuance of common stock upon vesting of restricted stock units, shares         896    
Issuance of common stock upon vesting of restricted stock units 0       $ 1 (1)  
Issuance of common stock under ESPP, shares         320    
Issuance of common stock under ESPP 1,979         1,979  
Vesting of early exercised stock options 0            
Stock-based compensation 9,643         9,643  
Net loss (11,860)           (11,860)
Ending balance at Dec. 31, 2016 $ 30,328   $ 0   $ 53 $ 196,555 $ (166,280)
Ending balance, shares at Dec. 31, 2016     0   53,363