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Stock-Based Compensation (Tables) | 3 Months Ended
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Mar. 31, 2023
Schedule of stock-based compensation expense recognized for employees and non-employees | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended | ​
​ | ​ | March 31, | ​
By Expense Category: |  | 2023 |  | 2022 | ​
Research and development | ​ | $ | 581 | ​ | $ | 383 | ​
General and administrative | ​ |  | 1,971 | ​ |  | 3,802 | ​
Total stock-based compensation expense | ​ | $ | 2,552 | ​ | $ | 4,185 | ​
​
Schedule of unamortized compensation expense and weighted average remaining recognition period | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | As of March 31, 2023
​ | ​ | ​ | ​ | ​ | Weighted
​ | ​ | ​ | ​ | ​ | Average
​ | ​ | ​ | ​ | ​ | Remaining
​ | ​ | ​ | ​ | ​ | Recognition
​ |  | Unamortized |  | Period
​ | ​ | Expense | ​ | (Years)
Stock options | ​ | $ | 19,293 |  | 2.9
Restricted stock units | ​ | $ | 10,692 | ​ | 3.6
​
Schedule of assumptions used for estimating the fair value of stock options | ​
​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended
​ | ​ | March 31,
​ |  | 2023 |  | 2022
Expected dividend yield | ​ | — | ​ | —
Risk-free interest rate |  | 3.46% - 3.64% |  | 1.46% - 2.34%
Expected volatility |  | 94% - 95% |  | 90% - 92%
Expected life (years) |  | 5.9 - 6.1 |  | 6.0 - .6.1
​
Schedule of stock option activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ |  | ​ | ​ |  | Weighted |  | ​ | ​
​ | ​ | ​ | ​ | Weighted | ​ | Average | ​ | ​ | ​
​ | ​ | ​ | ​ | Average | ​ | Contractual | ​ | Aggregate
​ | ​ | Number of | ​ | Exercise | ​ | Term | ​ | Intrinsic
​ | ​ | Shares | ​ | Price | ​ | (in years) | ​ | Value
Outstanding as of December 31, 2022 |  | 8,398,262 | ​ | $ | 4.49 |  |  |  | ​ |
Granted |  | 1,144,146 | ​ | ​ | 6.17 |  |  |  | ​ |
Exercised |  | (21,447) | ​ | ​ | 3.68 |  |  |  | ​ |
Cancelled |  | (6,120) | ​ | ​ | 2.97 |  |  |  | ​ |
Outstanding as of March 31, 2023 |  | 9,514,841 | ​ | $ | 4.69 |  | 8.5 | ​ | $ | 22,693
Exercisable as of March 31, 2023 |  | 4,366,134 | ​ | $ | 4.27 |  | 7.8 | ​ | $ | 13,072
Vested and expected to vest as of March 31, 2023 |  | 9,112,607 | ​ | $ | 4.69 |  | 8.5 | ​ | $ | 21,845
​
Schedule of non vested RSU awards outstanding | ​
​ | ​ | ​ | ​ | ​ | ​
​ |  |  |  | Weighted
​ | ​ | ​ | ​ | Average
​ | ​ | ​ | ​ | Grant-Date
​ | ​ | Number of | ​ | Fair Value
​ | ​ | RSUs | ​ | (per RSU)
Unvested as of December 31, 2022 |  | 407,726 | ​ | $ | 5.57
Granted |  | 1,483,166 | ​ |  | 6.48
Vested |  | (89,804) | ​ |  | 6.00
Forfeited |  | (1,617) | ​ |  | 6.75
Unvested as of March 31, 2023 |  | 1,799,471 | ​ | $ | 6.30
Employee Stock Purchase Plan |
Schedule of assumptions used for estimating the fair value of stock options | ​
​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended
​ | ​ | March 31,
​ |  | 2023 |  | 2022
Expected dividend yield | ​ | — | ​ | —
Risk-free interest rate | ​ | 5.20% | ​ | 0.69%
Expected volatility | ​ | 64% | ​ | 80%
Expected life (years) | ​ | 0.50 | ​ | 0.50
​

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- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the changes in outstanding nonvested restricted stock units. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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