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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Operating activities    
Net loss $ (11,745) $ (15,943)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 2,552 4,185
Depreciation and amortization 569 947
Non-cash lease expense 91 70
(Gain) on disposal of property and equipment (2)  
Loss on extinguishment of debt 2,311 997
Non-cash interest expense (income) 953 (6)
Changes in operating assets and liabilities:    
Accounts receivable, net 886 (297)
Prepaid expenses and other current assets 214 (82)
Other noncurrent assets 0 4
Accounts payable (1,495) 458
Accrued expenses and other current liabilities (2,577) 70
Operating lease liabilities (214) (185)
Net cash used in operating activities (8,457) (9,782)
Investing activities    
Purchases of property, plant and equipment (366)  
Proceeds from the sale of property, plant and equipment 2 0
Net cash used in investing activities (364) 0
Financing activities    
Proceeds from revenue interest financing, net 31,814  
Principal payments on long-term debt (20,000) (10,500)
Payments for debt prepayment and extinguishment costs (2,190) 0
Proceeds from issuance of long-term debt with warrants, net 0 19,767
Principal payments on finance leases (105) (82)
Receipts from litigation financing 17 276
Proceeds from issuance of common stock under stock incentive plans 414 621
Net cash provided by financing activities 9,950 10,082
Net increase in cash and cash equivalents 1,129 300
Cash and cash equivalents, beginning of period 93,283 57,494
Cash and cash equivalents, end of period 94,412 57,794
Supplemental disclosure of cash flow information    
Cash paid for interest 360 261
Cash paid for operating lease liabilities 319 309
Non-cash increase in property, plant and equipment through accounts payable 122  
Non-cash increase in indemnification asset through accounts payable $ 17 $ 138