<SEC-DOCUMENT>0001415889-23-005801.txt : 20230403
<SEC-HEADER>0001415889-23-005801.hdr.sgml : 20230403
<ACCEPTANCE-DATETIME>20230403164217
ACCESSION NUMBER:		0001415889-23-005801
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20230331
FILED AS OF DATE:		20230403
DATE AS OF CHANGE:		20230403

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Aspbury Robert
		CENTRAL INDEX KEY:			0001834221

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39799
		FILM NUMBER:		23793365

	MAIL ADDRESS:	
		STREET 1:		100 OVERLOOK CENTER, SUITE 101
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08540

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Certara, Inc.
		CENTRAL INDEX KEY:			0001827090
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-PREPACKAGED SOFTWARE [7372]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		100 OVERLOOK CENTER, SUITE 101
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08540
		BUSINESS PHONE:		(609) 716-7900

	MAIL ADDRESS:	
		STREET 1:		100 OVERLOOK CENTER, SUITE 101
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08540
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>form4-04032023_080407.xml
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    <schemaVersion>X0407</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2023-03-31</periodOfReport>

    <issuer>
        <issuerCik>0001827090</issuerCik>
        <issuerName>Certara, Inc.</issuerName>
        <issuerTradingSymbol>CERT</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001834221</rptOwnerCik>
            <rptOwnerName>Aspbury Robert</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O CERTARA, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>100 OVERLOOK CENTER, SUITE 101</rptOwnerStreet2>
            <rptOwnerCity>PRINCETON</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>08540</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>false</isDirector>
            <isOfficer>true</isOfficer>
            <isTenPercentOwner>false</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle>PRESIDENT, SIMCYP</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <aff10b5One>0</aff10b5One>

    <nonDerivativeTable>
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                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2023-03-31</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>F</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
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                <transactionShares>
                    <value>2870</value>
                    <footnoteId id="F1"/>
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                <transactionPricePerShare>
                    <value>23.80</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
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                <transactionPricePerShare>
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                <sharesOwnedFollowingTransaction>
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                <directOrIndirectOwnership>
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            <securityTitle>
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            <transactionDate>
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        </nonDerivativeTransaction>
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    <derivativeTable>
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            <conversionOrExercisePrice>
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                    <value>8646</value>
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                <transactionPricePerShare>
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                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
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            <exerciseDate>
                <footnoteId id="F3"/>
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            <expirationDate>
                <value>2025-04-01</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>8646</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
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                    <value>17293</value>
                </sharesOwnedFollowingTransaction>
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                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Restricted Stock Units</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F5"/>
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            <transactionDate>
                <value>2023-04-01</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>M</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>23556</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F5"/>
            </exerciseDate>
            <expirationDate>
                <value>2026-04-01</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>23556</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>23556</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Represents restricted stock units (&quot;RSUs&quot;) withheld to satisfy the tax withholding obligations in connection with the vesting and settlement of RSUs, exempt under Rule 16b-3.  Each RSUs was granted on April 1, 2021, under the Certara, Inc. 2020 Incentive Plan (the &quot;2020 Incentive Plan&quot;) and represents a right to receive one share of common stock or the cash equivalent thereof.  One-third of the RSUs vested and were settled on April 1, 2022.  One-third of the RSUs vested and were on March 31, 2023.  The remaining one-third of the RSUs are scheduled to vest and settle on April 1, 2024.</footnote>
        <footnote id="F2">The total reported in Column 5 includes 9,769 RSUs which was previously reported in Table 1 of Form 4.</footnote>
        <footnote id="F3">Each RSU was granted on April 1, 2022, under the 2020 Incentive Plan and represents a right to receive one share of common stock or the cash equivalent thereof.  One-third of the RSUs vested and were settled on March 31, 2023.  The remaining two-thirds of the RSUs are scheduled to vest and settle in two equal installments on April 1, 2024, and April 1, 2025.</footnote>
        <footnote id="F4">Represents  RSUs withheld to satisfy the tax withholding obligations in connection with the vesting and settlement of RSUs, exempt under Rule 16b-3.</footnote>
        <footnote id="F5">Each RSU was granted on April 1, 2023, under the 2020 Incentive Plan and represents a right to receive one share of common stock or the cash equivalent thereof.  The RSUs will vest and settle in three equal installments on April 1, 2024, April 1, 2025, and April 1, 2026.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Richard M. Traynor as attorney in fact for Robert Aspbury</signatureName>
        <signatureDate>2023-04-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
