<SEC-DOCUMENT>0001209191-16-142355.txt : 20160921
<SEC-HEADER>0001209191-16-142355.hdr.sgml : 20160921
<ACCEPTANCE-DATETIME>20160921212819
ACCESSION NUMBER:		0001209191-16-142355
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20160919
FILED AS OF DATE:		20160921
DATE AS OF CHANGE:		20160921

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Sarepta Therapeutics, Inc.
		CENTRAL INDEX KEY:			0000873303
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				930797222
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		215 FIRST STREET
		STREET 2:		SUITE 415
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
		BUSINESS PHONE:		617-274-4000

	MAIL ADDRESS:	
		STREET 1:		215 FIRST STREET
		STREET 2:		SUITE 415
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Sarepta Therapuetics, Inc.
		DATE OF NAME CHANGE:	20120712

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AVI BIOPHARMA INC
		DATE OF NAME CHANGE:	19980930

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ANTIVIRALS INC
		DATE OF NAME CHANGE:	19970123

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Howton David T
		CENTRAL INDEX KEY:			0001529297

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14895
		FILM NUMBER:		161896578

	MAIL ADDRESS:	
		STREET 1:		VERTEX PHARMACEUTICALS INCORPORATED
		STREET 2:		130 WAVERLY STREET
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
</SEC-HEADER>
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<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
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        <issuerName>Sarepta Therapeutics, Inc.</issuerName>
        <issuerTradingSymbol>SRPT</issuerTradingSymbol>
    </issuer>

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            <rptOwnerName>Howton David T</rptOwnerName>
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        <reportingOwnerAddress>
            <rptOwnerStreet1>215 FIRST STREET, SUITE 415</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>SVP, General Counsel</officerTitle>
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        <derivativeTransaction>
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                <value>Non-Qualified Stock Options (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>13.90</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2016-09-19</value>
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                <transactionShares>
                    <value>8000</value>
                    <footnoteId id="F1"/>
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                <transactionPricePerShare>
                    <value>13.90</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2016-02-27</value>
            </exerciseDate>
            <expirationDate>
                <value>2025-02-27</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>8000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
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                <sharesOwnedFollowingTransaction>
                    <value>72007</value>
                </sharesOwnedFollowingTransaction>
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    <footnotes>
        <footnote id="F1">This transaction was effected pursuant to a Rule 10b5-1 Plan adopted by the reporting person, on March 16, 2016, accordingly, the reporting person had no discretion with regards to the timing of the transaction.</footnote>
        <footnote id="F2">100% of the Restricted Stock Award (&quot;RSA&quot;) granted on September 19, 2016 vests six months from the date of grant. The Company will withhold the shares to satisfy the executive's tax obligation upon vesting.</footnote>
        <footnote id="F3">15,300 RSAs vest upon the Company exceeding $80 million in total revenue reported in publicly released GAAP financials, in any fiscal quarter between grant date and June 30, 2018, with an additional 3,825 RSAs vesting during the same period if the total revenue reported in the publicly released GAAP financials exceeds $100 million. The Company will withhold the shares to satisfy the executive's tax obligation upon vesting.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>David Tyronne Howton</signatureName>
        <signatureDate>2016-09-21</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
