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Stock Based Compensation - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands | 1 Months Ended | 3 Months Ended
--- | --- | ---
Jun. 30, 2017 | Mar. 31, 2023 | Mar. 31, 2022
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |  |  |
Stock-based compensation expense |  | $ 41,250 | $ 29,198
Stock-based compensation expenses |  | $ 41,300 | $ 29,200
Grants, Stock options |  | 1,030,349 | 1,291,537
Chief Executive Officer |  |  |
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |  |  |
Grants, Stock options | 3,300,000 |  |
Minimum [Member] |  |  |
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |  |  |
Compound annual growth rate |  | 5.00% |
Unvested Tranche Member |  |  |
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |  |  |
Stock-based compensation expense |  | $ 8,400 |
Incremental compensation cost |  | $ 5,000 |
Vesting, Stock options |  | 550,110 |
Average closing price |  | $ 128.65 |
Share-Based Compensation Arrangement by Share-Based Payment Award, Terms of Award |  | 550,110 options relating to the Unvested Tranche met the conditions for vesting as the average closing price of the Company's common stock exceeded $128.65 during 20 consecutive trading days in March 2023 and the compound annual growth rate of the Company's common stock exceeded that of the Nasdaq Biotech Index by greater than 5% |

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