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Stock-Based Compensation - Summary of Stock-Based Compensation Expense by Grant Type Included within Condensed Consolidated Statements of Operations and Comprehensive Loss (Detail) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
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Jun. 30, 2024 | Jun. 30, 2023 | Jun. 30, 2024 | Jun. 30, 2023
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |  |
Total stock-based compensation expense |  | $ 50,500 | $ 47,400 | $ 91,200 | $ 88,600
Total stock-based compensation expense included in expenses |  | 50,482 | 47,377 | 91,174 | 88,627
Subtotal |  | 55,654 | 47,377 | 100,859 | 88,627
Capitalized stock-based compensation costs | [1] | (5,172) | 0 | (9,685) | 0
Research and Development Expense |  |  |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |  |
Total stock-based compensation expense included in expenses |  | 19,806 | 21,577 | 36,079 | 37,990
Selling, General and Administrative |  |  |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |  |
Total stock-based compensation expense included in expenses |  | 30,676 | 25,800 | 55,095 | 50,637
Employee Stock Option |  |  |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |  |
Total stock-based compensation expense included in expenses |  | 15,515 | 21,135 | 31,796 | 44,965
Restricted stock units |  |  |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |  |
Total stock-based compensation expense included in expenses |  | 37,808 | 25,037 | 65,335 | 41,177
Employee Stock Purchase Plan |  |  |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |  |
Total stock-based compensation expense included in expenses |  | $ 2,331 | $ 1,205 | $ 3,728 | $ 2,485
[1] | Prior to the six months ended June 30, 2024, capitalized stock-based compensation costs were not material.

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