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Income Taxes - Components of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands | Dec. 31, 2022 | Dec. 31, 2021
--- | --- | ---
Deferred tax assets |  |
Net operating losses | $ 63,702 | $ 74,463
Research tax credits | 78,340 | 80,468
Foreign tax credits | 29,077 | 69,637
Expenses not currently deductible | 18,823 | 14,434
Fixed and intangible assets |  | 207
Deferred revenue | 8,428 | 6,385
Capitalized research expenses | 38,806 | 34,963
Lease liability | 1,598 | 1,715
Gross deferred tax assets | 238,774 | 282,272
Valuation allowance | (120,508) | (178,731)
Net deferred tax assets | 118,266 | 103,541
Deferred tax liabilities |  |
Revenue recognition | (4,288) | (1,445)
Operating leases | (1,388) | (1,508)
Acquired intangible assets | (74,075) | (101,679)
Other | (3,237) | (4,076)
Net deferred tax assets | $ 35,278 |
Net deferred tax liabilities |  | $ (5,167)

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