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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $)
In Thousands, unless otherwise specified
 9 Months Ended 282 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Operating activities:      
Net loss $ (22,824) $ (16,879) $ (263,704)
Adjustments to reconcile net loss to net cash used for operating activities:      
Depreciation and amortization 487 464 7,985
Loss on property held for resale     110
Amortization of discounts and premiums on investments     (1,704)
Stock compensation expense 3,166 2,767 17,051
Decrease in fair value of warrants (3,289) (4,286) (15,578)
Inventory write downs and reserves     2,240
Stock issued pursuant to license agreement     3,300
Provision for losses on accounts receivable     204
Changes in operating assets and liabilities:      
Receivables   16 (258)
Inventories     (2,335)
Other current assets 272 (196) (344)
Accounts payable and accrued expenses 281 (452) 3,012
Accrued employee benefits (300) 218 742
Net cash used for operating activities (22,207) (18,348) (249,279)
Investing activities:      
Organizational costs     (73)
Purchase of short-term investments     (217,041)
Maturities of short-term investments     218,745
Property and equipment purchases (169) (803) (7,386)
Proceeds from sale of property held for resale     400
Net cash used for investing activities (169) (803) (5,355)
Financing activities:      
Net proceeds from issuance of preferred stock 37,620   89,267
Net proceeds from issuance of common stock and warrants 346 32 185,054
Payments received for stock purchase rights and other, net     3,500
Proceeds from long-term debt     751
Principal payments under long-term debt obligations (31) (182) (2,831)
Other, net     (18)
Net cash provided by (used for) financing activities 37,935 (150) 275,723
Net increase (decrease) in cash and cash equivalents 15,559 (19,301) 21,089
Cash and cash equivalents at beginning of period 5,530 31,248  
Cash and cash equivalents at end of period 21,089 11,947 21,089
Supplemental cash flow information (non-cash):      
Accretion of convertible preferred stock 2,738   3,706
Warrants exchanged for common stock $ 10,382   $ 10,382