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CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $) In Thousands, unless otherwise specified | 12 Months Ended
--- | ---
Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2010
Cash Flows From Operating Activities: |  |  |
Net Loss | $ (59,123) | $ (44,799) | $ (2,533)
Adjustments to Reconcile Net Loss to Cash Used in Operating Activities: |  |  |
Depreciation and Amortization | 2,047 | 2,248 | 2,718
Amortization of Intangible Assets | 1,090 | 1,913 | 3,143
Amortization and Premium of Marketable Securities | (660) | 17 | (14)
Realized (Gain) Loss on Sales and Maturities of Marketable Securities | (6) | 5 | (4)
Gain on Sale or Disposal of Assets | (74) | (58) | (38)
Stock-Based Compensation Expense | 2,298 | 2,342 | 2,802
Non-Cash Interest Expense | 226 | 307 | 728
Changes in Operating Assets and Liabilities: |  |  |
Accounts and Other Receivables | 126 | 154 | 220
Prepaid and Other Current Assets | 33 | 241 | (546)
Other Assets | (95) | 34 | 5,592
Accounts Payable and Accrued Expenses | 3,762 | 2,076 | (1,193)
Deferred Revenue |  |  | (39,382)
Other Liabilities | 594 | (138) | (1,865)
Net Cash Used in Operating Activities | (49,782) | (35,658) | (30,372)
Cash Flows From Investing Activities: |  |  |
Sales and Maturities of Marketable Securities | 52,360 | 51,003 | 42,383
Purchases of Marketable Securities | (69,255) | (52,717) | (56,522)
Acquisition of Property and Equipment | (303) | (509) | (2,100)
Proceeds from Sale or Disposal of Assets | 218 | 68 | 77
Net Cash Used in Investing Activities | (16,980) | (2,155) | (16,162)
Cash Flows From Financing Activities: |  |  |
Net Proceeds from Stock Issuances | 83,784 | 36,023 | 1,014
(Payments) Issuance of Term Loan | (3,971) | 5,000 | 10,000
Payment of Convertible Subordinated Debt |  | (12,503) |
Payment of Other Liabilities | (55) | (86) | (197)
Net Cash Provided by Financing Activities | 79,758 | 28,434 | 10,817
Effect of Exchange Rate Changes on Cash and Cash Equivalents | 2 | (9) | 2
Net Increase (Decrease) in Cash and Cash Equivalents | 12,998 | (9,388) | (35,715)
Cash and Cash Equivalents at Beginning of Period | 11,899 | 21,287 | 57,002
Cash and Cash Equivalents at End of Period | 24,897 | 11,899 | 21,287
Supplemental Disclosure of Cash Flow Information |  |  |
Cash Paid for Interest | $ 1,384 | $ 1,560 | $ 604

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- Definition The sum of the periodic adjustments of the differences between securities' face values and purchase prices that are charged against earnings. This is called accretion if the security was purchased at a discount and amortization if it was purchased at premium. As a noncash item, this element is an adjustment to net income when calculating cash provided by or used in operations using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=6943989&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 95 -Paragraph 28 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. + Details
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- Definition Amount of noncash expense included in interest expense to amortize debt discount and premium associated with the related debt instruments. Excludes amortization of financing costs. Alternate captions include noncash interest expense. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.8) -URI http://asc.fasb.org/extlink&oid=6880815&loc=d3e20235-122688 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 03 -Paragraph 8 -Article 5 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 835 -SubTopic 30 -Section 45 -Paragraph 1A -URI http://asc.fasb.org/extlink&oid=6451184&loc=d3e28541-108399 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher AICPA -Name Accounting Principles Board Opinion (APB) -Number 21 -Paragraph 16 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6943989&loc=d3e3602-108585 + Details
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