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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (USD $) In Thousands, except Share data, unless otherwise specified | Total | Common Stock | Additional Paid-In Capital | Accumulated Other Comprehensive Income | Accumulated Deficit
--- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2009 | $ 73,767 | $ 32 | $ 228,863 | $ 2,546 | $ (157,674)
Balance (in shares) at Dec. 31, 2009 |  | 31,685,061 |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Shares Issued under Stock Option and Employee Stock Purchase Plans | 1,014 |  | 1,014 |  |
Shares Issued under Stock Option and Employee Stock Purchase Plans (in shares) |  | 370,321 |  |  |
Share-Based Compensation | 2,802 |  | 2,802 |  |
Foreign Currency Translation Adjustments | 2 |  |  | 2 |
Unrealized Gains (Losses) on Marketable Securities | 203 |  |  | 203 |
Net Loss | (2,533) |  |  |  | (2,533)
Balance at Dec. 31, 2010 | 75,255 | 32 | 232,679 | 2,751 | (160,207)
Balance (in shares) at Dec. 31, 2010 |  | 32,055,382 |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Shares Issued under Stock Option and Employee Stock Purchase Plans | 173 |  | 173 |  |
Shares Issued under Stock Option and Employee Stock Purchase Plans (in shares) |  | 80,254 |  |  |
Shares Issued in Connection with Cantor Agreement | 2,155 | 1 | 2,154 |  |
Shares Issued in Connection with Cantor Agreement (in Shares) |  | 575,000 |  |  |
Shares Issued in Underwritten Offering | 33,695 | 11 | 33,684 |  |
Shares Issued in Underwritten Offering (in shares) |  | 11,500,000 |  |  |
Share-Based Compensation | 2,342 |  | 2,342 |  |
Foreign Currency Translation Adjustments | (9) |  |  | (9) |
Unrealized Gains (Losses) on Marketable Securities | (90) |  |  | (90) |
Net Loss | (44,799) |  |  |  | (44,799)
Balance at Dec. 31, 2011 | 68,722 | 44 | 271,032 | 2,652 | (205,006)
Balance (in shares) at Dec. 31, 2011 | 44,210,636 | 44,210,636 |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Shares Issued under Stock Option and Employee Stock Purchase Plans | 163 |  | 163 |  |
Shares Issued under Stock Option and Employee Stock Purchase Plans (in shares) |  | 70,587 |  |  |
Shares Issued in Connection with Cantor Agreement | 40,138 | 8 | 40,130 |  |
Shares Issued in Connection with Cantor Agreement (in Shares) |  | 8,003,290 |  |  |
Shares Issued in Underwritten Offering | 43,483 | 12 | 43,471 |  |
Shares Issued in Underwritten Offering (in shares) |  | 12,075,000 |  |  |
Share-Based Compensation | 2,298 |  | 2,298 |  |
Foreign Currency Translation Adjustments | 2 |  |  | 2 |
Unrealized Gains (Losses) on Marketable Securities | 91 |  |  | 91 |
Net Loss | (59,123) |  |  |  | (59,123)
Balance at Dec. 31, 2012 | $ 95,774 | $ 64 | $ 357,094 | $ 2,745 | $ (264,129)
Balance (in shares) at Dec. 31, 2012 | 64,359,513 | 64,359,513 |  |  |

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- Definition Total number of common shares of an entity that have been sold or granted to shareholders (includes common shares that were issued, repurchased and remain in the treasury). These shares represent capital invested by the firm's shareholders and owners, and may be all or only a portion of the number of shares authorized. Shares issued include shares outstanding and shares held in the treasury. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.29) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 30 -Article 5 + Details
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