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INCOME TAXES (Details) (USD $) In Thousands, unless otherwise specified | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2012 | Sep. 30, 2012 | Jun. 30, 2012 | Mar. 31, 2012 | Dec. 31, 2011 | Sep. 30, 2011 | Jun. 30, 2011 | Mar. 31, 2011 | Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2010
Income tax benefit (provision): |  |  |  |  |  |  |  |  |  |  |
Federal |  |  |  |  |  |  |  |  | $ 19,394 | $ 16,204 | $ 1,512
State |  |  |  |  |  |  |  |  | 4,237 | 3,131 | 779
Foreign |  |  |  |  |  |  |  |  |  | 84 | 107
Expiration of Net Operating Losses and Research & Development Tax Credits |  |  |  |  |  |  |  |  | (1,426) | (411) | (13,924)
Income tax benefit (provision) attributable to continuing operations |  |  |  |  |  |  |  |  | 22,205 | 19,008 | (11,526)
Deferred tax valuation allowance |  |  |  |  |  |  |  |  | (22,205) | (19,008) | 11,526
Income tax benefit (provision) |  |  |  |  |  |  |  |  | 0 |  |
Reconciliation between the amount of reported income tax and the amount computed using U.S. Statutory rate |  |  |  |  |  |  |  |  |  |  |
U.S. Statutory rate (as a percent) |  |  |  |  |  |  |  |  | 34.00% |  |
Pre-tax loss | (16,807) | (15,027) | (13,773) | (13,516) | (12,732) | (11,772) | (10,236) | (10,059) | (59,123) | (44,799) | (2,533)
Loss at Statutory Rates |  |  |  |  |  |  |  |  | (20,102) | (15,213) | (838)
Research and Development Credits |  |  |  |  |  |  |  |  |  | (1,736) | (1,498)
State Taxes |  |  |  |  |  |  |  |  | (4,237) | (3,131) | (779)
Other |  |  |  |  |  |  |  |  | 708 | 661 | 717
Expiration of Net Operating Losses and Research & Development Tax Credits |  |  |  |  |  |  |  |  | 1,426 | 411 | 13,924
Change in Valuation Allowance |  |  |  |  |  |  |  |  | 22,205 | 19,008 | (11,526)
Income tax benefit (provision) |  |  |  |  |  |  |  |  | 0 |  |
Gross Deferred Tax Assets |  |  |  |  |  |  |  |  |  |  |
Net Operating Loss Carryforwards | 67,728 |  |  |  | 58,802 |  |  |  | 67,728 | 58,802 |
Tax Credit Carryforwards | 20,692 |  |  |  | 20,285 |  |  |  | 20,692 | 20,285 |
Deferred Expenses | 43,226 |  |  |  | 31,002 |  |  |  | 43,226 | 31,002 |
Stock-based Compensation | 3,264 |  |  |  | 3,184 |  |  |  | 3,264 | 3,184 |
Fixed Assets | 2,156 |  |  |  | 2,029 |  |  |  | 2,156 | 2,029 |
Accrued Expenses and Other | 241 |  |  |  | 197 |  |  |  | 241 | 197 |
Gross Deferred Tax Assets | 137,307 |  |  |  | 115,499 |  |  |  | 137,307 | 115,499 |
Gross Deferred Tax Liabilities |  |  |  |  |  |  |  |  |  |  |
Other Acquired Intangibles | (4,481) |  |  |  | (4,878) |  |  |  | (4,481) | (4,878) |
IPR&D Intangibles | (4,661) |  |  |  | (4,661) |  |  |  | (4,661) | (4,661) |
Gross Deferred Tax Liabilities | (9,142) |  |  |  | (9,539) |  |  |  | (9,142) | (9,539) |
Total Deferred Tax Assets and Liabilities | 128,165 |  |  |  | 105,960 |  |  |  | 128,165 | 105,960 |
Deferred Tax Assets Valuation Allowance | (132,826) |  |  |  | (110,621) |  |  |  | (132,826) | (110,621) |
Net Deferred Tax Asset (Liability) | $ (4,661) |  |  |  | $ (4,661) |  |  |  | $ (4,661) | $ (4,661) |

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