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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (USD $) In Thousands, except Per Share data, unless otherwise specified | 3 Months Ended
--- | ---
Mar. 31, 2013 | Mar. 31, 2012
REVENUE: |  |
Product Development and Licensing Agreements | $ 30 | $ 35
Contracts and Grants | 50 | 54
Product Royalties | 2,334 | 2,344
Total Revenue | 2,414 | 2,433
OPERATING EXPENSE: |  |
Research and Development | 14,090 | 10,769
Royalty | 2,334 | 2,344
General and Administrative | 3,138 | 2,317
Amortization of Acquired Intangible Assets | 253 | 291
Total Operating Expense | 19,815 | 15,721
Operating Loss | (17,401) | (13,288)
Investment and Other Income, Net | 379 | 205
Interest Expense | (310) | (433)
Net Loss | (17,332) | (13,516)
Basic and Diluted Net Loss Per Common Share (Note 3) (in dollars per share) | $ (0.23) | $ (0.27)
Shares Used in Calculating Basic and Diluted Net Loss per Share (Note 3) (in shares) | 74,027 | 50,145
COMPREHENSIVE INCOME: |  |
Net Loss | (17,332) | (13,516)
Other Comprehensive (Loss) Income: |  |
Foreign Currency Translation Adjustments | (2) | 2
Unrealized (Loss) Gain on Marketable Securities | (54) | 108
Comprehensive Loss | $ (17,388) | $ (13,406)

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