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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2023 | Sep. 30, 2022 | Sep. 30, 2023 | Sep. 30, 2022
Revenues: |  |  |  |
Total revenues | $ 1,517 | $ 407 | $ 2,752 | $ 744
Operating expenses: |  |  |  |
Research and development | 34,535 | 21,572 | 87,585 | 59,359
General and administrative | 8,221 | 6,531 | 22,082 | 20,596
Gain on fair value remeasurement of contingent consideration | 0 | (0) | 0 | (6,862)
Litigation settlement related loss |  |  |  | 15,000
Total operating expenses | 42,756 | 28,103 | 109,667 | 88,093
Operating loss | (41,239) | (27,696) | (106,915) | (87,349)
Investment and other income, net | 2,979 | 912 | 8,792 | 1,511
Net loss | $ (38,260) | $ (26,784) | $ (98,123) | $ (85,838)
Basic net loss per common share | $ (0.81) | $ (0.57) | $ (2.08) | $ (1.83)
Diluted net loss per common share | $ (0.81) | $ (0.57) | $ (2.08) | $ (1.83)
Shares used in calculating basic net loss per share | 47,261 | 46,916 | 47,243 | 46,806
Shares used in calculating diluted net loss per share | 47,261 | 46,916 | 47,243 | 46,806
Comprehensive loss: |  |  |  |
Net loss | $ (38,260) | $ (26,784) | $ (98,123) | $ (85,838)
Other comprehensive income (loss): |  |  |  |
Unrealized gain (loss) on marketable securities | 63 | 305 | 875 | (2,006)
Comprehensive loss | (38,197) | (26,479) | (97,248) | (87,844)
Product development and licensing agreements |  |  |  |
Revenues: |  |  |  |
Total revenues | 2 |  | 19 | 30
Contracts and grants |  |  |  |
Revenues: |  |  |  |
Total revenues | $ 1,515 | $ 407 | $ 2,733 | $ 714

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