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Stockholders' Equity | 9 Months Ended
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Sep. 30, 2023
Stockholders' Equity |
Stockholders' Equity | (7) Stockholders’ Equity ​ In May 2016, the Company entered into a controlled equity offering sales agreement (the “Cantor Agreement”) with Cantor Fitzgerald & Co. (“Cantor”) to allow the Company to issue and sell shares of its common stock from time to time through Cantor, acting as agent. At September 30, 2023, the Company had $50.0 million remaining in aggregate gross offering price available under the Company’s November 2020 prospectus. ​ The changes in Stockholders’ Equity during the three and nine months ended September 30, 2023 and 2022 are summarized below: ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ |  | ​ | ​ |  | ​ | ​ |  | Accumulated |  | ​ | ​ |  | ​ | ​
​ | ​ | Common | ​ | Common | ​ | Additional | ​ | Other | ​ | ​ | ​ | ​ | Total
​ | ​ | Stock | ​ | Stock Par | ​ | Paid-In | ​ | Comprehensive | ​ | Accumulated | ​ | Stockholders’
​ |  | Shares |  | Value |  | Capital |  | Income |  | Deficit |  | Equity
​ | ​ | (In thousands, except share amounts)
Consolidated balance at December 31, 2022 |  | 47,200,695 |  | $ | 47 |  | $ | 1,580,829 |  | $ | 1,260 |  | $ | (1,255,932) |  | $ | 326,204
Shares issued under stock option and employee stock purchase plans |  | 43,986 |  |  | — |  |  | 694 |  |  | — |  |  | — |  |  | 694
Stock-based compensation |  | — |  |  | — |  |  | 4,340 |  |  | — |  |  | — |  |  | 4,340
Unrealized gain on marketable securities |  | — |  |  | — |  |  | — |  |  | 863 |  |  | — |  |  | 863
Net loss |  | — |  |  | — |  |  | — |  |  | — |  |  | (29,361) | ​ |  | (29,361)
Consolidated balance at March 31, 2023 |  | 47,244,681 |  | $ | 47 |  | $ | 1,585,863 |  | $ | 2,123 |  | $ | (1,285,293) |  | $ | 302,740
Shares issued under stock option and employee stock purchase plans | ​ | 9,132 | ​ | ​ | — | ​ | ​ | 133 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 133
Stock-based compensation | ​ | — | ​ | ​ | — | ​ | ​ | 5,217 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 5,217
Unrealized loss on marketable securities | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | (51) | ​ | ​ | — | ​ | ​ | (51)
Net loss | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | (30,502) | ​ | ​ | (30,502)
Consolidated balance at June 30, 2023 | ​ | 47,253,813 | ​ | $ | 47 | ​ | $ | 1,591,213 | ​ | $ | 2,072 | ​ | $ | (1,315,795) | ​ | $ | 277,537
Shares issued under stock option and employee stock purchase plans | ​ | 10,384 | ​ | ​ | — | ​ | ​ | 257 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 257
Stock-based compensation | ​ | — | ​ | ​ | — | ​ | ​ | 7,121 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 7,121
Unrealized gain on marketable securities | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 63 | ​ | ​ | — | ​ | ​ | 63
Net loss | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | (38,260) | ​ | ​ | (38,260)
Consolidated balance at September 30, 2023 | ​ | 47,264,197 | ​ | $ | 47 | ​ | $ | 1,598,591 | ​ | $ | 2,135 | ​ | $ | (1,354,055) | ​ | $ | 246,718
​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ |  | ​ | ​ |  | ​ | ​ |  | Accumulated |  | ​ | ​ |  | ​ | ​
​ | ​ | Common | ​ | Common | ​ | Additional | ​ | Other | ​ | ​ | ​ | ​ | Total
​ | ​ | Stock | ​ | Stock Par | ​ | Paid-In | ​ | Comprehensive | ​ | Accumulated | ​ | Stockholders’
​ | ​ | Shares | ​ | Value | ​ | Capital | ​ | Income | ​ | Deficit | ​ | Equity
​ | ​ | (In thousands, except share amounts)
Consolidated balance at December 31, 2021 |  | 46,730,198 | ​ | $ | 47 | ​ | $ | 1,561,142 | ​ | $ | 1,894 | ​ | $ | (1,143,607) | ​ | $ | 419,476
Shares issued under stock option and employee stock purchase plans |  | 24,150 | ​ |  | — | ​ |  | 304 | ​ |  | — | ​ |  | — | ​ |  | 304
Stock-based compensation |  | — | ​ |  | — | ​ |  | 3,153 | ​ |  | — | ​ |  | — | ​ |  | 3,153
Unrealized loss on marketable securities |  | — | ​ |  | — | ​ |  | — | ​ |  | (1,782) | ​ |  | — | ​ |  | (1,782)
Net loss |  | — | ​ |  | — | ​ |  | — | ​ |  | — | ​ |  | (23,050) | ​ |  | (23,050)
Consolidated balance at March 31, 2022 |  | 46,754,348 | ​ | $ | 47 | ​ | $ | 1,564,599 | ​ | $ | 112 | ​ | $ | (1,166,657) | ​ | $ | 398,101
Shares issued under stock option and employee stock purchase plans |  | 10,355 | ​ |  | — | ​ |  | 71 | ​ |  | — | ​ |  | — | ​ |  | 71
Stock-based compensation |  | — | ​ |  | — | ​ |  | 3,454 | ​ |  | — | ​ |  | — | ​ |  | 3,454
Unrealized loss on marketable securities |  | — | ​ |  | — | ​ |  | — | ​ |  | (529) | ​ |  | — | ​ |  | (529)
Net loss |  | — | ​ |  | — | ​ |  | — | ​ |  | — | ​ |  | (36,004) | ​ |  | (36,004)
Consolidated balance at June 30, 2022 |  | 46,764,703 | ​ | $ | 47 | ​ | $ | 1,568,124 | ​ | $ | (417) | ​ | $ | (1,202,661) | ​ | $ | 365,093
Shares issued under stock option and employee stock purchase plans | ​ | 331,360 | ​ | ​ | — | ​ | ​ | 2,306 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 2,306
Stock-based compensation | ​ | — | ​ | ​ | — | ​ | ​ | 4,496 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 4,496
Unrealized gain on marketable securities | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 305 | ​ | ​ | — | ​ | ​ | 305
Net loss | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | (26,784) | ​ | ​ | (26,784)
Consolidated balance at September 30, 2022 | ​ | 47,096,063 | ​ | $ | 47 | ​ | $ | 1,574,926 | ​ | $ | (112) | ​ | $ | (1,229,445) | ​ | $ | 345,416
​

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