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Stockholders' Equity (Details) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended
--- | --- | ---
Mar. 31, 2024 | Nov. 30, 2023 | Mar. 31, 2024 | Mar. 31, 2023
Increase (Decrease) in Stockholders' Equity |  |  |  |
Balance, beginning |  |  | $ 429,171 | $ 326,204
Balance, beginning (in shares) |  |  | 55,883,377 |
Shares issued under stock option and employee stock purchase plans |  |  | $ 3,814 | 694
Shares issued in underwritten offering, net |  |  | 432,298 |
Stock-based compensation |  |  | 7,202 | 4,340
Unrealized (loss) gain on marketable securities |  |  | (1,064) | 863
Net loss |  |  | (32,808) | (29,361)
Balance, ending | $ 838,613 |  | $ 838,613 | 302,740
Balance, ending (in shares) | 65,910,548 |  | 65,910,548 |
Net proceeds from sale of common stock |  |  | $ 432,298 |
Underwritten Public Offering |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |
Common stock issued (in shares) | 9,798,000 | 8,538,750 |  |
Net proceeds from sale of common stock | $ 432,300 | $ 216,200 |  |
Common Stock |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |
Balance, beginning |  |  | $ 56 | $ 47
Balance, beginning (in shares) |  |  | 55,883,377 | 47,200,695
Shares issued under stock option and employee stock purchase plans (in shares) |  |  | 229,171 | 43,986
Shares issued in underwritten offering, net |  |  | $ 10 |
Shares issued in underwritten offering, net (in shares) |  |  | 9,798,000 |
Balance, ending | $ 66 |  | $ 66 | $ 47
Balance, ending (in shares) | 65,910,548 |  | 65,910,548 | 47,244,681
Additional Paid-In Capital |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |
Balance, beginning |  |  | $ 1,823,168 | $ 1,580,829
Shares issued under stock option and employee stock purchase plans |  |  | 3,814 | 694
Shares issued in underwritten offering, net |  |  | 432,288 |
Stock-based compensation |  |  | 7,202 | 4,340
Balance, ending | $ 2,266,472 |  | 2,266,472 | 1,585,863
Accumulated Other Comprehensive Income |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |
Balance, beginning |  |  | 3,308 | 1,260
Unrealized (loss) gain on marketable securities |  |  | (1,064) | 863
Balance, ending | 2,244 |  | 2,244 | 2,123
Accumulated Deficit |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |
Balance, beginning |  |  | (1,397,361) | (1,255,932)
Net loss |  |  | (32,808) | (29,361)
Balance, ending | $ (1,430,169) |  | $ (1,430,169) | $ (1,285,293)

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