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Nature of Business and Overview (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Nature of Business and Overview
Cash, cash equivalents and marketable securities	$ 725,300
Net loss	(157,863)	$ (141,429)	$ (112,325)
Net cash used in operations	$ (157,778)	$ (107,291)	$ (103,732)

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Sum of investments and unrestricted cash as of the balance sheet date.

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