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Segment Information | 6 Months Ended
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Jun. 30, 2025
Segment Information |
Segment Information | (3) Segment Information The Company is managed as a single operating and reportable segment that operates in the business of development, manufacturing and commercialization of novel therapeutics for human health care. Our chief operating decision maker (“CODM”), the Chief Executive Officer, evaluates performance based on consolidated net loss. Other than general and administrative expenses as presented on the consolidated statement of operations, research and development expense disaggregated by program and by nature are considered to be the Company’s significant segment expenses. These results are used, in part, by our CODM in evaluating the performance of the Company by comparing budget to actual results, and to allocate resources. All revenue is derived in and long-lived assets are located in the United States. The CODM does not receive asset information other than what is presented on the consolidated balance sheets. The following table is a summary of the Company’s research and development expenses disaggregated by program. The amounts disclosed reflect direct research and development costs and an allocation of indirect research and development costs to each program. ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended | ​ | Three Months Ended | ​ | Six Months Ended | ​ | Six Months Ended
​ |  | June 30, 2025 |  | June 30, 2024 |  | June 30, 2025 |  | June 30, 2024
​ | ​ | (In thousands)
Barzolvolimab/Anti-KIT Program | ​ | $ | 42,645 | ​ | $ | 30,472 | ​ | $ | 82,348 | ​ | $ | 54,250
CDX-622 | ​ |  | 3,838 | ​ |  | 3,126 | ​ |  | 9,289 | ​ |  | 6,547
Other Programs (a) | ​ |  | 7,713 | ​ |  | 6,089 | ​ |  | 15,173 | ​ |  | 10,551
Total R&D Expense | ​ | $ | 54,196 | ​ | $ | 39,687 | ​ | $ | 106,810 | ​ | $ | 71,348
​
| (a) | Other program expenses primarily include research and development expenses related to early-stage programs, revenue-generating programs and discontinued programs.
The following table is a summary of the Company’s research and development expenses disaggregated by nature. ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended | ​ | Three Months Ended | ​ | Six Months Ended | ​ | Six Months Ended
​ |  | June 30, 2025 |  | June 30, 2024 |  | June 30, 2025 |  | June 30, 2024
​ |  | (In thousands)
Personnel | ​ | $ | 14,129 | ​ | $ | 11,881 | ​ | $ | 27,729 | ​ | $ | 23,321
Laboratory supplies | ​ |  | 1,544 | ​ |  | 1,615 | ​ |  | 3,712 | ​ |  | 2,923
Facility | ​ |  | 1,398 | ​ |  | 1,250 | ​ |  | 2,803 | ​ |  | 2,536
Product development (b) | ​ |  | 33,536 | ​ |  | 22,667 | ​ |  | 65,702 | ​ |  | 38,192
Other expenses (c) | ​ |  | 3,589 | ​ |  | 2,274 | ​ |  | 6,864 | ​ |  | 4,376
Total R&D expense | ​ | $ | 54,196 | ​ | $ | 39,687 | ​ | $ | 106,810 | ​ | $ | 71,348
​
| (b) | Product development expenses include clinical investigator site fees, external trial monitoring costs, data accumulation costs, contracted research and outside clinical drug product manufacturing.
| (c) | Other expenses primarily include research and development consulting, insurance, licensing and software expenses.

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