<SUBMISSION>
<ACCESSION-NUMBER>0001181431-08-032956
<TYPE>4
<PUBLIC-DOCUMENT-COUNT>1
<PERIOD>20080516
<FILING-DATE>20080520
<DATE-OF-FILING-DATE-CHANGE>20080520
<ISSUER>
<COMPANY-DATA>
<CONFORMED-NAME>AtriCure, Inc.
<CIK>0001323885
<ASSIGNED-SIC>3841
<IRS-NUMBER>341940305
<STATE-OF-INCORPORATION>DE
<FISCAL-YEAR-END>1231
</COMPANY-DATA>
<BUSINESS-ADDRESS>
<STREET1>6033 SCHUMACHER PARK DRIVE
<CITY>WEST CHESTER
<STATE>OH
<ZIP>45069
<PHONE>513-755-4107
</BUSINESS-ADDRESS>
<MAIL-ADDRESS>
<STREET1>6033 SCHUMACHER PARK DRIVE
<CITY>WEST CHESTER
<STATE>OH
<ZIP>45069
</MAIL-ADDRESS>
</ISSUER>
<REPORTING-OWNER>
<OWNER-DATA>
<CONFORMED-NAME>Wrubel Lee R
<CIK>0001336092
</OWNER-DATA>
<FILING-VALUES>
<FORM-TYPE>4
<ACT>34
<FILE-NUMBER>000-51470
<FILM-NUMBER>08849205
</FILING-VALUES>
<BUSINESS-ADDRESS>
<PHONE>(203) 851-3900
</BUSINESS-ADDRESS>
<MAIL-ADDRESS>
<STREET1>105 ROWAYTON AVENUE
<CITY>ROWAYTON
<STATE>CT
<ZIP>06853
</MAIL-ADDRESS>
</REPORTING-OWNER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd207642.xml
<DESCRIPTION>FORM 4
<TEXT>
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                <directOrIndirectOwnership>
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                <transactionPricePerShare>
                    <value>11.23</value>
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                <transactionAcquiredDisposedCode>
                    <value>D</value>
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                <sharesOwnedFollowingTransaction>
                    <value>296677</value>
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            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
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                <transactionShares>
                    <value>900</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>11.24</value>
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                <transactionAcquiredDisposedCode>
                    <value>D</value>
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            <ownershipNature>
                <directOrIndirectOwnership>
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                <transactionShares>
                    <value>60</value>
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                <transactionPricePerShare>
                    <value>11.26</value>
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            <ownershipNature>
                <directOrIndirectOwnership>
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                <natureOfOwnership>
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    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Dr. Wrubel is a general partner of Foundation Medical Partners, LP. Dr. Wrubel disclaims beneficial ownership of the securities held by Foundation Medical Partners, LP, except as to his pecuniary interest therein.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Lee R. Wrubel</signatureName>
        <signatureDate>2008-05-20</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SUBMISSION>
