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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Cash flows from operating activities:    
Net loss $ (17,066) $ (17,930)
Adjustments to reconcile net loss to net cash used in operating activities:    
Share-based compensation expense 7,325 5,869
Depreciation 3,906 3,678
Amortization of intangible assets 684 822
Amortization of deferred financing costs 132 86
Loss on disposal of property and equipment 88 117
Realized gain from foreign exchange on intercompany transactions (10) (15)
Amortization/accretion on investments 59 74
Change in allowance for doubtful accounts (134) (49)
Changes in operating assets and liabilities:    
Accounts receivable (1,673) (1,897)
Inventories (2,094) (1,595)
Other current assets (26) (236)
Accounts payable 565 131
Accrued liabilities (1,891) (5,673)
Other noncurrent assets and liabilities (468) (338)
Net cash used in operating activities (10,603) (16,956)
Cash flows from investing activities:    
Purchases of available-for-sale securities (7,567) (21,940)
Maturities of available-for-sale securities 16,350 12,404
Purchases of property and equipment (3,488) (4,341)
Net cash provided by (used in) investing activities 5,295 (13,877)
Cash flows from financing activities:    
Proceeds from debt borrowings 25,000
Payments on capital leases (241) (218)
Payment of debt fees (50) (120)
Proceeds from stock option exercises 3,074 2,301
Shares repurchased for payment of taxes on stock awards (1,901) (1,033)
Proceeds from issuance of common stock under employee stock purchase plan 1,205 987
Net cash provided by financing activities 2,087 26,917
Effect of exchange rate changes on cash and cash equivalents 26 69
Net decrease in cash and cash equivalents (3,195) (3,847)
Cash and cash equivalents-beginning of period 24,208 23,764
Cash and cash equivalents-end of period 21,013 19,917
Supplemental cash flow information:    
Cash paid for interest 985 577
Cash paid for income taxes
Non-cash investing and financing activities:    
Accrued purchases of property and equipment 703 306
Assets acquired through capital lease 43
Capital lease asset early termination $ 9