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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows from operating activities:    
Net loss $ (30,024) $ (33,168)
Adjustments to reconcile net loss to net cash used in operating activities:    
Share-based compensation expense 14,573 13,745
Depreciation 3,861 3,815
Amortization of intangible assets 1,943 965
Amortization of deferred financing costs 255 249
Loss on disposal of property and equipment 25 52
Amortization of investments 983 1,206
Change in fair value of contingent consideration 0 5,100
Other non-cash adjustments 654 472
Changes in operating assets and liabilities:    
Accounts receivable (8,757) (10,799)
Inventories (2,727) (2,707)
Other current assets 32 (308)
Accounts payable 4,240 3,571
Accrued liabilities (5,136) 4,529
Other noncurrent assets and liabilities (325) (571)
Net cash used in operating activities (20,403) (13,849)
Cash flows from investing activities:    
Purchases of available-for-sale securities (3,941) (94,817)
Sales and maturities of available-for-sale securities 51,749 147,884
Purchases of property and equipment (7,565) (5,539)
Net cash provided by investing activities 40,243 47,528
Cash flows from financing activities:    
Payments on leases (437) (399)
Proceeds from stock option exercises and employee stock purchase plan 3,374 9,010
Shares repurchased for payment of taxes on stock awards (11,573) (16,500)
Net cash used in financing activities (8,636) (7,889)
Effect of exchange rate changes on cash and cash equivalents (302) (115)
Net increase in cash and cash equivalents 10,902 25,675
Cash and cash equivalents—beginning of period 43,654 41,944
Cash and cash equivalents—end of period 54,556 67,619
Supplemental cash flow information:    
Cash paid for interest 1,797 2,147
Cash paid for income taxes, net of refunds 132 128
Non-cash investing and financing activities:    
Accrued purchases of property and equipment $ 2,562 $ 529