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Staff numbers and costs (Tables)
 12 Months Ended
Dec. 31, 2020
Staff numbers and costs [Abstract]  
Average number of persons employed by group
The average number of persons employed by the Group (including the Board) during the year, analyzed by category, was as follows:

  
2020
No. of employees
  
2019
No. of employees
  
2018
No. of employees
 
Research
  
177
   
284
   
299
 
Development
  
96
   
108
   
95
 
Corporate
  
56
   
67
   
67
 
Total
  
329
   
459
   
461
 
Aggregate staff costs
The aggregate staff costs of these persons were as follows:

 
2020
£’000
  
2019
£’000
  
2018
£’000
 
Wages and salaries
  
29,038
   
31,920
   
29,501
 
Social security costs
  
2,131
   
2,767
   
2,731
 
Share-based payments (Note 25)
  
8,162
   
3,056
   
666
 
Contributions to defined contribution plans (Note 27)
  
1,035
   
1,213
   
981
 
   
40,366
   
38,956
   
33,879