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Operating loss is stated after charging (Details) - GBP (£)
£ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Operating loss is stated after charging [Abstract]      
Research and development costs £ 74,809 £ 99,991 £ 83,575
Loss on disposal of property, plant and equipment 1,064 3 135
Profit on derecognition of leases (Note 12) (3,700) 0 0
Remeasurement of leases (Note 12) (227) 0 0
Loss on write-offs of intangible fixed assets 0 306 170
Depreciation of property, plant and equipment (Note 11) 6,446 9,003 6,410
Amortization of intangible assets (Note 10) 0 210 297
Operating lease expense (Note 12) 296 486 4,205
Operating lease income (see Note 5) 460 185 622
Realised foreign exchange (gains)/loss 477 189 (1,341)
Research and development expenditure credit £ 227 £ 396 £ 237