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Finance costs (Details)		12 Months Ended
	Nov. 06, 2020 GBP (£)	Dec. 31, 2020 GBP (£)	Dec. 31, 2019 GBP (£)	Dec. 31, 2018 GBP (£)	Nov. 06, 2020 USD ($)
Finance costs [Abstract]
Interest on lease liabilities		£ 2,401,000	£ 2,947,000	£ 0
Interest expenses on financial liabilities measured at amortized cost		708,000	849,000	842,000
Loss from change in fair value of embedded derivative asset		266,000	454,000	0
Loss from change in fair value of derivative liability		0	5,127,000	0
Other finance costs		0	2,000	0
Total finance costs		3,375,000	£ 9,379,000	£ 842,000
Oxford Debt Agreement [Member]
Finance costs [Abstract]
Interest expense	£ 549,000,000
Debt instrument face amount | $					$ 50,000,000
Gates Foundation [Member]
Finance costs [Abstract]
Interest expense		£ 159,000,000

X

- Definition

Adjustments for decrease (increase) in derivative financial assets to reconcile profit (loss) to net cash flow from (used in) operating activities. [Refer: Derivative financial assets; Profit (loss)]

+ References

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- Definition

The amount of costs associated with financing activities of the entity.

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The amount of expense arising from interest.

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The amount of interest expense for financial liabilities that are not at fair value through profit or loss. [Refer: At fair value [member]; Interest expense; Financial liabilities]

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The amount of interest expense on lease liabilities. [Refer: Lease liabilities]

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The nominal or face amount of a financial instrument, used to calculate payments made on that instrument.

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The amount of finance costs that the entity does not separately disclose in the same statement or note. [Refer: Finance costs]

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The loss resulting from change in the fair value of derivative liability.

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