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Leases (Details) - GBP (£)
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Maturity Analysis Contractual Undiscounted Cash Flows [Abstract]      
Total undiscounted lease liabilities £ 45,767,000 £ 66,591,000  
Lease Liabilities Included in Consolidated Statements of Financial Position [Abstract]      
Current 2,043,000 1,951,000  
Non-current 25,190,000 38,299,000  
Total lease liabilities 27,233,000 40,250,000  
Amounts Recognized in Consolidated Statements of Loss [Abstract]      
Interest on lease liabilities 2,401,000 2,947,000 £ 0
Expenses relating to short-term leases 296,000 486,000 4,205,000
Expenses relating to leases of low-value assets 19,000 33,000  
Interest on investment in sub-lease (38,000) (9,000) 0
Operating Lease Rentals Payable [Abstract]      
Future minimum rentals payable under non-cancellable operating leases 0 73,000 81,586,000
Amounts recognized in Consolidated Statement of Cash Flows [Abstract]      
Total cash outflow for leases 4,426,000 4,036,000  
Lease income [Abstract]      
Operating lease income 460,000 185,000 622,000
Operating lease income 460,000    
Finance lease income on the net investment in the lease 38,000 9,000  
Two Terminated Leasehold Properties [Member]      
Lease Liabilities Included in Consolidated Statements of Financial Position [Abstract]      
Total lease liabilities 10,414,000    
Four Remeasured Leasehold Properties [Member]      
Lease Liabilities Included in Consolidated Statements of Financial Position [Abstract]      
Total lease liabilities 1,075,000    
New Leasehold Property [Member]      
Lease Liabilities Included in Consolidated Statements of Financial Position [Abstract]      
Total lease liabilities 405,000    
Less than One Year [Member]      
Maturity Analysis Contractual Undiscounted Cash Flows [Abstract]      
Total undiscounted lease liabilities 3,560,000 4,469,000  
Operating Lease Rentals Payable [Abstract]      
Future minimum rentals payable under non-cancellable operating leases 0 73,000 4,329,000
One to Five Years [Member]      
Maturity Analysis Contractual Undiscounted Cash Flows [Abstract]      
Total undiscounted lease liabilities 9,607,000 16,834,000  
Operating Lease Rentals Payable [Abstract]      
Future minimum rentals payable under non-cancellable operating leases 0 0 16,566,000
More than Five Years [Member]      
Maturity Analysis Contractual Undiscounted Cash Flows [Abstract]      
Total undiscounted lease liabilities 32,600,000 45,288,000  
Operating Lease Rentals Payable [Abstract]      
Future minimum rentals payable under non-cancellable operating leases £ 0 £ 0 £ 60,691,000