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Current interest-bearing loans and borrowings (Details)
Dec. 31, 2020
GBP (£)
Mar. 31, 2020
USD ($)
shares
Mar. 02, 2020
USD ($)
shares
Dec. 31, 2019
GBP (£)
Dec. 31, 2019
USD ($)
Sep. 13, 2017
USD ($)
Current Interest-Bearing Loans and Borrowings [Abstract]            
Short-term convertible loan (Note 26) £ 0     £ 19,157,000    
Interest-bearing loans and borrowings 0     19,157,000    
Disclosure of current liabilities [Abstract]            
Borrowings outstanding £ 36,654,000     0    
Gates foundation convertible loan [Member]            
Disclosure of current liabilities [Abstract]            
Maximum borrowing capacity | $         $ 40,000,000 $ 40,000,000
Loan amount received | $           25,000,000
Stock converted (in shares) | shares   203,697        
Derivative asset, derecognized       266,000    
Derivative asset, in accumulated deficit       510,000    
Loans, carrying value       £ 19,356,000    
Borrowings outstanding | $   $ 25,000,000 $ 25,000,000   $ 25,500,000  
Gates foundation convertible loan [Member] | Series B Shares [Member]            
Disclosure of current liabilities [Abstract]            
Stock converted (in shares) | shares   203,697 203,697      
Gates foundation convertible loan [Member] | First tranche [Member]            
Disclosure of current liabilities [Abstract]            
Loan amount received | $           $ 25,000,000
Borrowings outstanding | $     $ 25,000,000