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Unaudited Condensed Consolidated Statements of Cash Flows - GBP (£)
 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Cash flows from operating activities    
Loss for the period £ (30,774,000) £ (22,249,000)
Adjustments for:    
Equity settled share-based payment expense 13,651,000 14,088,000
Depreciation 2,601,000 3,317,000
Net finance (income) / costs (2,773,000) 2,602,000
Foreign exchange movements 9,106,000 (8,808,000)
Other (187,000) (131,000)
Income tax charge / (credit) 387,000 (3,806,000)
Working capital adjustments:    
Increase in trade and other receivables and other non-current assets (3,562,000) (19,951,000)
Increase in trade and other payables 12,177,000 11,474,000
Decrease in current and non-current deferred revenue (3,204,000) (15,905,000)
Other working capital movements (748,000) (648,000)
Cash used in operations (3,326,000) (40,017,000)
R&D tax credits received 9,904,000 0
Taxation paid (177,000) 0
Net cash from / (used in) operating activities 6,401,000 (40,017,000)
Cash flows from investing activities    
Proceeds from sale of property, plant and equipment 0 5,000
Purchase of property, plant and equipment (3,238,000) (475,000)
Interest income receipts 5,550,000 128,000
Net cash flows from / (used in) investing activities 2,312,000 (342,000)
Cash flows from financing activities    
Exercise of share options 14,207,000 1,384,000
Interest paid (3,559,000) (1,805,000)
Repayment of lease liabilities (805,000) (1,449,000)
Net cash flows from / (used in) financing activities 9,843,000 (1,870,000)
Increase / (decrease) in cash and cash equivalents 18,556,000 (42,229,000)
Net foreign exchange difference on cash held (8,754,000) 12,407,000
Cash and cash equivalents at beginning of the period 332,539,000 237,886,000
Cash and cash equivalents at end of the period £ 342,341,000 £ 208,064,000