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Share-based compensation (Tables) | 3 Months Ended
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Mar. 31, 2026
Share-Based Payment Arrangement [Abstract] |
Schedule of Share-based Compensation Expense Recorded in Consolidated Statements of Operations and Comprehensive Loss | The following table shows the total share-based compensation expense recorded in the Condensed Consolidated Statements of Operations and Comprehensive Income (Loss) (in thousands):
|  | Three Months Ended March 31,
|  | 2026 |  | 2025
Research and development |  | $ | 2,572 |  |  | $ | 2,181 |
Selling, general and administrative |  | $ | 3,730 |  |  | $ | 7,308 |
Schedule of Number and Weighted Average Exercise Prices of Share Options Activity | The number and weighted average exercise prices of share options were as follows:
| Number of Share Options |  | Weighted Average Exercise Price |  | Weighted Average Remaining Contractual Term |  | Aggregate Intrinsic Value (in thousands)
Outstanding as of December 31, 2025 | 10,374,316 |  | $ | 31.34 |  |  | 5.9 years |  | $ | 87,338 |
Awards granted | 1,387,755 |  | 32.45 |  |  |  |  |
Awards exercised | (27,334) |  | 22.76 |  |  |  |  |
Awards forfeited | (204,570) |  | 46.15 |  |  |  |  |
Awards expired | (43,926) |  | 42.74 |  |  |  |  |
Outstanding as of March 31, 2026 | 11,486,241 |  | $ | 31.18 |  |  | 5.8 years |  | $ | 48,937 |
Exercisable as of March 31, 2026 | 8,315,349 |  | $ | 28.99 |  |  | 4.5 years |  | $ | 48,149 |
Schedule of Assumptions Used in Determining Fair Value of Stock Options | Awards granted in the three months ended March 31, 2026 and 2025 have been valued using the Black-Scholes option pricing model. The assumptions used in the models for share options granted were as follows:
|  | Three Months Ended March 31,
|  | 2026 |  | 2025
Share price at grant date |  | $32.38 - $34.71 |  | $29.21 - $29.60
Exercise price |  | $32.38 - $34.71 |  | $29.21 - $29.60
Expected volatility |  | 51.08% - 53.52% |  | 53.30% - 55.78%
Expected life |  | 5.5 years |  | 5.5 years
Risk free rate |  | 3.68% - 3.78% |  | 4.14% - 4.41%
Fair value |  | $16.94 - $17.62 |  | $15.70 - $16.21
Schedule of Number and Weighted Average Fair Value of RSUs Awards | The number and weighted average fair value of RSU awards were as follows:
| Number of RSUs |  | Weighted Average Grant Date Fair Value
Unvested and outstanding as of December 31, 2025 | 496,156 |  |  | $ | 29.88 |
Awards granted | 557,683 |  | 32.46 |
Awards vested | (114,671) |  |  | 29.60 |
Awards forfeited | (44,842) |  |  | 29.77 |
Unvested and outstanding as of March 31, 2026 | 894,326 |  |  | $ | 31.53 |

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- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (e) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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