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Condensed Statements of Cash Flows - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2024 | Jun. 30, 2023
Cash flows from operating activities |  |
Net loss | $ (60,022) | $ (44,307)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation | 953 | 619
Stock-based compensation | 10,095 | 7,848
Amortization (accretion) of (discount) on marketable securities, net | (6,703) | (4,970)
Amortization of right-of-use asset | 106 | 83
Changes in assets and liabilities: |  |
Prepaid expenses and other assets | 914 | (2,017)
Accounts payable | 2,673 | (472)
Accrued compensation | (1,451) | (907)
Accrued other expenses and other liabilities | (927) | 947
Lease liability | (335) | 116
Net cash used in operating activities | (54,697) | (43,060)
Cash flows from investing activities |  |
Purchases of marketable securities | (368,558) | (131,413)
Sales of marketable securities | 1,759 | 5,146
Maturities of marketable securities | 136,377 | 183,878
Purchases of property and equipment | (518) | (5,127)
Net cash (used in) provided by investing activities | (230,940) | 52,484
Cash flows from financing activities |  |
Proceeds from issuance of common stock, net of underwriting discounts and commissions and offering costs | 239,147 |
Exercise of stock options | 3,503 | 52
Payment of deferred offering costs | (48) |
Proceeds from Employee Stock Purchase Plan | 423 | 338
Net cash provided by financing activities | 243,025 | 390
Net change in cash and cash equivalents | (42,612) | 9,814
Cash and cash equivalents at beginning of period | 86,097 | 21,993
Cash and cash equivalents at end of period | 43,485 | 31,807
Supplemental disclosures of non-cash investing and financing activities: |  |
Right-of-use asset obtained in exchange for new operating lease liability, net of tenant improvement receivable |  | 1,118
Property and equipment purchases included in accounts payable and accrued other expenses | 116 | 324
Deferred offering costs included in accounts payable and accrued other expenses | $ 214 | $ 168

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