<SEC-DOCUMENT>0001104659-24-004960.txt : 20240119
<SEC-HEADER>0001104659-24-004960.hdr.sgml : 20240119
<ACCEPTANCE-DATETIME>20240119060418
ACCESSION NUMBER:		0001104659-24-004960
CONFORMED SUBMISSION TYPE:	S-3MEF
PUBLIC DOCUMENT COUNT:		7
<REFERENCE-462B>333-264083
FILED AS OF DATE:		20240119
DATE AS OF CHANGE:		20240119
EFFECTIVENESS DATE:		20240119

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Edgewise Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001710072
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				821725586
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3MEF
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-276595
		FILM NUMBER:		24543645

	BUSINESS ADDRESS:	
		STREET 1:		1715 38TH ST
		CITY:			BOULDER
		STATE:			CO
		ZIP:			80301
		BUSINESS PHONE:		720-262-7002

	MAIL ADDRESS:	
		STREET 1:		1715 38TH ST
		CITY:			BOULDER
		STATE:			CO
		ZIP:			80301
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3MEF
<SEQUENCE>1
<FILENAME>tm243583d1_s3mef.htm
<DESCRIPTION>S-3MEF
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>As filed with the Securities and Exchange Commission
on January&nbsp;19, 2024</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"><B>Registration No.&nbsp;333-&emsp;&emsp;&emsp;</B></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>UNITED STATES</B></P>

<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Washington, D.C. 20549</B></P>

<P STYLE="border-bottom: Black 1pt solid; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>FORM&nbsp;S-3</B></P>

<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>REGISTRATION STATEMENT</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><I>UNDER</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><I>THE SECURITIES ACT OF 1933</I></B></P>

<P STYLE="border-bottom: Black 1pt solid; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 24pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Edgewise Therapeutics,&nbsp;Inc.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(Exact name of registrant as specified in its
charter)</B></P>

<P STYLE="border-bottom: Black 1pt solid; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>



<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center; width: 50%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Delaware</B></FONT></TD>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center; width: 50%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>82-1725586</B></FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(State or other jurisdiction of</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>incorporation or organization)</B></P></TD>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(I.R.S. Employer</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Identification Number)</B></P></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>1715 38<SUP>th</SUP> St.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Boulder, CO 80301</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(720) 262-7002</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(Address, including zip code, and telephone
number, including area code, of registrant&rsquo;s principal executive offices)</B></P>

<P STYLE="border-bottom: Black 1pt solid; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Kevin Koch, Ph.D.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>President and Chief Executive Officer</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Edgewise Therapeutics,&nbsp;Inc.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>1715 38<SUP>th</SUP> St.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Boulder, CO 80301</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(720) 262-7002</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(Name, address, including zip code, and telephone
number, including area code, of agent for service)</B></P>

<P STYLE="border-bottom: Black 1pt solid; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>



<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><I>Copies to:</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 50%; padding-right: 5.4pt; padding-left: 5.4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B></B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Kenneth A. Clark</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Tony Jeffries</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Jennifer Knapp</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Wilson Sonsini Goodrich&nbsp;&amp; Rosati,</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Professional Corporation</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>1881 9<SUP>th</SUP> Street, Suite&nbsp;110</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Boulder, CO 80302</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(303) 256-5900&nbsp;</B></P></TD>
    <TD STYLE="width: 50%; padding-right: 5.4pt; padding-left: 5.4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B></B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>R. Michael Carruthers</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Chief Financial Officer</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Edgewise Therapeutics,&nbsp;Inc.</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>1715 38<SUP>th</SUP> St.</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Boulder, CO 80301</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(720) 262-7002</B></P></TD></TR>
  </TABLE>
<P STYLE="border-bottom: Black 1pt solid; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>From time to time after the effective date
of the registration statement.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(Approximate date of commencement of proposed
sale to the public)</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">If the only securities being registered
on this Form&nbsp;are being offered pursuant to dividend or interest reinvestment plans, please check the following box:&ensp;</FONT>&#9744;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">If any of the securities being registered
on this Form&nbsp;are to be offered on a delayed or continuous basis pursuant to Rule&nbsp;415 under the Securities Act of 1933, other
than securities offered only in connection with dividend or interest reinvestment plans, check the following box.&ensp;</FONT><FONT STYLE="font-family: Wingdings">&#120;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">If
this Form&nbsp;is filed to register additional securities for an offering pursuant to Rule&nbsp;462(b)&nbsp;under the Securities Act,
please check the following box and list the Securities Act registration statement number of the earlier effective registration statement
for the same offering.&ensp;</FONT><FONT STYLE="font-family: Times New Roman, Times, Serif"><FONT STYLE="font-family: Wingdings">&#120;</FONT></FONT> (File no. 333-264083)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">If this Form&nbsp;is a post-effective
amendment filed pursuant to Rule&nbsp;462(c)&nbsp;under the Securities Act, please check the following box and list the Securities Act
registration statement number of the earlier effective registration statement for the same offering.&ensp;</FONT>&#9744;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">If this Form&nbsp;is a registration statement
pursuant to General Instruction I.D. or a post-effective amendment thereto that shall become effective upon filing with the Commission
pursuant to Rule&nbsp;462(e)&nbsp;under the Securities Act, check the following box.&ensp;</FONT>&#9744;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">If this Form&nbsp;is a post-effective
amendment to a registration statement filed pursuant to General Instruction I.D. filed to register additional securities or additional
classes of securities pursuant to Rule&nbsp;413(b)&nbsp;under the Securities Act, check the following box.&ensp;</FONT>&#9744;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Indicate by check mark whether the registrant is a large accelerated
filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions
of &ldquo;large accelerated filer,&rdquo; &ldquo;accelerated filer,&rdquo; &ldquo;smaller reporting company&rdquo; and &ldquo;emerging
growth company&rdquo; in Rule&nbsp;12b-2 of the Exchange Act.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="font-size: 10pt; width: 45%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Large accelerated filer</FONT></TD>
    <TD STYLE="font-size: 10pt; width: 5%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="font-size: 10pt; width: 45%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Accelerated filer</FONT></TD>
    <TD STYLE="text-align: right; font-size: 10pt; width: 5%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><FONT STYLE="font-family: Wingdings">&#168;</FONT></FONT></TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Non-accelerated filer</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><FONT STYLE="font-family: Wingdings">&#120;</FONT></FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Smaller reporting company</FONT></TD>
    <TD STYLE="text-align: right; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><FONT STYLE="font-family: Wingdings">&#120;</FONT></FONT></TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Emerging growth company</FONT></TD>
    <TD STYLE="text-align: right; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><FONT STYLE="font-family: Wingdings">&#120;</FONT></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-size: 10pt">If an emerging growth company, indicate
by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial
accounting standards provided pursuant to Section&nbsp;7(a)(2)(B)&nbsp;of Securities Act.&ensp;</FONT>&#9744;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>This Registration Statement shall become effective upon filing with
the Securities and Exchange Commission in accordance with Rule&nbsp;462(b)&nbsp;of the Securities Act.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 12pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 1pt solid; border-bottom: Black 2pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 1 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>EXPLANATORY NOTE AND INCORPORATION BY REFERENCE</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">Pursuant to Rule&nbsp;462(b)&nbsp;under the
Securities Act of 1933, as amended, and General Instruction IV(A)&nbsp;of Form&nbsp;S-3, the registrant is filing this Registration
Statement on Form&nbsp;S-3 to register the offer and sale of an additional $37,919,578.05, or the equivalent thereof, of its
(a)&nbsp; shares of the Company&rsquo;s common stock, $0.0001 par value per share (the &ldquo;Common Stock&rdquo;);
(b)&nbsp;shares of the Company&rsquo;s preferred stock, $0.0001 par value per share (the &ldquo;Preferred Stock&rdquo;);
(c)&nbsp;the Company&rsquo;s debt securities (the &ldquo;Debt Securities&rdquo;); (d)&nbsp;depositary shares of the Company
representing a fractional interest in a share of Preferred Stock (the &ldquo;Depositary Shares&rdquo;); (e)&nbsp;warrants to
purchase Common Stock, Preferred Stock, Debt Securities or Depositary Shares (the &ldquo;Warrants&rdquo;); (f)&nbsp;subscription
rights to purchase Common Stock, Preferred Stock, Debt Securities, Depositary Shares, Warrants or units consisting of some or all of
these securities (the &ldquo;Subscription Rights&rdquo;); (g)&nbsp;purchase contracts of the Company with respect to the securities
of the Company (the &ldquo;Purchase Contracts&rdquo;); and (h)&nbsp;units consisting of two or more securities described above in
any combination (the &ldquo;Units&rdquo;) (the Common Stock, the Preferred Stock, the Debt Securities, the Depositary Shares, the
Warrants, the Subscription Rights, the Purchase Contracts and the Units are collectively referred to herein as the
 &ldquo;Securities&rdquo;). This Registration Statement relates to the registrant&rsquo;s Registration Statement on <A HREF="https://www.sec.gov/Archives/edgar/data/1710072/000110465922041797/tm2210736d1_s3.htm" STYLE="-sec-extract: exhibit">Form&nbsp;S-3</A>
(File No.&nbsp;333-264083) (the &ldquo;Prior Registration Statement&rdquo;), initially filed on April&nbsp;1, 2022 and declared
effective by the Securities and Exchange Commission on May&nbsp;5, 2022. The required opinion and consents are filed herewith. The
additional amount of Securities that is being registered for offer and sale represents no more than 20% of the maximum aggregate
offering price of the remaining securities available to be sold under the Prior Registration Statement. Pursuant to
Rule&nbsp;462(b), the contents of the Prior Registration Statement, including the exhibits thereto, are incorporated by reference
into this Registration Statement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 2; Options: NewSection; Value: 2 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><FONT STYLE="font-size: 10pt"><!-- Field: Sequence; Type: LowerRoman; Name: PageNo -->ii<!-- Field: /Sequence --></FONT></P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>EXHIBIT&nbsp;INDEX</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-bottom: black 1pt solid; white-space: nowrap; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Exhibit&nbsp;<BR>
    Number</B></FONT></TD>
    <TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="border-bottom: black 1pt solid; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Exhibit&nbsp;Description</B></FONT></TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; font-size: 10pt"><A HREF="tm243583d1_ex5-1.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.1</FONT></A></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt"><A HREF="tm243583d1_ex5-1.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Opinion
    of Wilson Sonsini Goodrich&nbsp;&amp; Rosati, Professional Corporation </FONT></A></TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; font-size: 10pt"><A HREF="tm243583d1_ex23-1.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.1</FONT></A></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt"><A HREF="tm243583d1_ex23-1.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Consent
    of Independent Registered Public Accounting Firm </FONT></A></TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; font-size: 10pt"><A HREF="tm243583d1_ex5-1.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.2</FONT></A></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt"><A HREF="tm243583d1_ex5-1.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Consent
    of Wilson Sonsini Goodrich&nbsp;&amp; Rosati, Professional Corporation (included in Exhibit&nbsp;5.1) </FONT></A></TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="white-space: nowrap; vertical-align: top; font-size: 10pt"><A HREF="tm243583d1_ex-filingfees.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">107.1</FONT></A></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt"><A HREF="tm243583d1_ex-filingfees.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Filing
    Fee Table </FONT></A></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 3; Options: NewSection; Value: 1 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="text-align: center; margin-top: 0pt; margin-bottom: 0pt"><FONT STYLE="font-size: 10pt">II-<!-- Field: Sequence; Type: Arabic; Name: PageNo -->1<!-- Field: /Sequence --></FONT></P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>SIGNATURES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">Pursuant to the requirements of the Securities
Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form&nbsp;S-3
and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City
of Boulder, State of Colorado, on January&nbsp;19, 2024.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>EDGEWISE THERAPEUTICS,&nbsp;INC.</B></FONT></TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 45%">&nbsp;</TD>
    <TD STYLE="width: 50%">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">By:</FONT></TD>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; border-bottom: black 0.75pt solid">/s/ Kevin Koch</P></TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Kevin Koch, Ph.D.</FONT></TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">President and Chief Executive Officer</FONT></TD>
    <TD>&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.25in">Pursuant to the requirements of the Securities
Act of 1933, this registration statement has been signed by the following persons in the capacities and on the dates indicated:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="white-space: nowrap; border-bottom: black 1pt solid; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Signature</B></FONT></TD>
    <TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="border-bottom: black 1pt solid; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Title</B></FONT></TD>
    <TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="border-bottom: black 1pt solid; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Date</B></FONT></TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: bottom">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; border-bottom: black 0.75pt solid">/s/ Kevin Koch</P></TD>
    <TD ROWSPAN="2" STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD ROWSPAN="2" STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">President and Chief Executive Officer and Director</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(Principal Executive Officer)</P></TD>
    <TD ROWSPAN="2" STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD ROWSPAN="2" STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">January&nbsp;19, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Kevin Koch, Ph.D.</FONT></TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: bottom">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; border-bottom: black 0.75pt solid">/s/ R. Michael
    Carruthers</P></TD>
    <TD ROWSPAN="2" STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD ROWSPAN="2" STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Chief Financial Officer</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(Principal Financial and Accounting Officer)</P></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">January&nbsp;19, 2024</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">R. Michael Carruthers</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; border-bottom: black 0.75pt solid">*</P></TD>
    <TD ROWSPAN="2" STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD ROWSPAN="2" STYLE="vertical-align: top; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chairman and Director</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">January&nbsp;19, 2024</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Peter Thompson, M.D.</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; border-bottom: black 0.75pt solid">*</P></TD>
    <TD ROWSPAN="2" STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD ROWSPAN="2" STYLE="vertical-align: top; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">January&nbsp;19, 2024</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Laura Brege</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; border-bottom: black 0.75pt solid">*</P></TD>
    <TD ROWSPAN="2" STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD ROWSPAN="2" STYLE="vertical-align: top; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">January&nbsp;19, 2024</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Badreddin Edris, Ph.D.</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; border-bottom: black 0.75pt solid">&nbsp;</P></TD>
    <TD ROWSPAN="2" STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD ROWSPAN="2" STYLE="vertical-align: top; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">January&nbsp;19, 2024</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Jonathan C. Fox, M.D., Ph.D., FACC</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; border-bottom: black 0.75pt solid">*</P></TD>
    <TD ROWSPAN="2" STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD ROWSPAN="2" STYLE="vertical-align: top; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">January&nbsp;19, 2024</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Jonathan Root, M.D.</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
  <TR>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD>
    <TD COLSPAN="2">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; border-bottom: black 0.75pt solid">*</P></TD>
    <TD ROWSPAN="2" STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD ROWSPAN="2" STYLE="vertical-align: top; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">January&nbsp;19, 2024</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Alan Russell, Ph.D.</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="vertical-align: top; font-size: 10pt; width: 5%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">*By:</FONT></TD>
    <TD STYLE="vertical-align: top; width: 45%">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; border-bottom: black 0.75pt solid">/s/ Kevin Koch</P></TD>
    <TD STYLE="width: 50%">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Kevin Koch, Ph.D.</FONT></TD>
    <TD>&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: top">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">President and Chief Executive Officer</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Attorney-in-Fact</P></TD>
    <TD>&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 4; Options: Last -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>tm243583d1_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"><B>Exhibit 5.1 </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="vertical-align: top; font-size: 10pt; width: 45%"><IMG SRC="tm243583d1_ex5-1img01.jpg" ALT=""></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; width: 10%">&nbsp;</TD>
    <TD STYLE="vertical-align: top; width: 45%">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right">Wilson Sonsini Goodrich &amp; Rosati</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right">Professional Corporation</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right">1881 9th Street, Suite 110</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right">Boulder, Colorado 80302</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right">o: 303.256.5900</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right">f: 866.974.7329</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right">&nbsp;</P></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center">January 19, 2023</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Edgewise Therapeutics, Inc.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">1715 38<SUP>th</SUP> Street</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Boulder, Colorado 80301</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"><B>Re:</B></FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"><B><U>Registration Statement on Form S-3</U>&nbsp;</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Ladies and Gentlemen:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">This opinion is furnished to you in connection
with the Registration Statement on Form S-3 (the &#8220;<B><I>Registration Statement</I></B>&#8221;), filed by Edgewise Therapeutics,
Inc. (the &#8220;<B><I>Company</I></B>&#8221;) with the U.S. Securities and Exchange Commission (the &#8220;<B><I>Commission</I></B>&#8221;)
pursuant to Rule 462(b) of the Securities Act of 1933, as amended (the &#8220;<B><I>Securities Act</I></B>&#8221;), in connection with
the registration under the Securities Act of additional (a)&nbsp;shares of the Company&#8217;s common stock, $0.0001 par value per share
(the &#8220;<B><I>Common Stock</I></B>&#8221;); (b)&nbsp;shares of the Company&#8217;s preferred stock, $0.0001 par value per share (the
 &#8220;<B><I>Preferred Stock</I></B>&#8221;); (c)&nbsp;the Company&#8217;s debt securities (the &#8220;<B><I>Debt Securities</I></B>&#8221;);
(d)&nbsp;depositary shares of the Company representing a fractional interest in a share of Preferred Stock (the &#8220;<B><I>Depositary
Shares</I></B>&#8221;); (e)&nbsp;warrants to purchase Common Stock, Preferred Stock, Debt Securities or Depositary Shares (the &#8220;<B><I>Warrants</I></B>&#8221;);
(f)&nbsp;subscription rights to purchase Common Stock, Preferred Stock, Debt Securities, Depositary Shares, Warrants or units consisting
of some or all of these securities (the &#8220;<B><I>Subscription Rights</I></B>&#8221;); (g)&nbsp;purchase contracts of the Company with
respect to the securities of the Company (the &#8220;<B><I>Purchase Contracts</I></B>&#8221;); and (h)&nbsp;units consisting of two or
more securities described above in any combination (the &#8220;<B><I>Units</I></B>&#8221;) (the Common Stock, the Preferred Stock, the
Debt Securities, the Depositary Shares, the Warrants, the Subscription Rights, the Purchase Contracts and the Units are collectively referred
to herein as the &#8220;<B><I>Securities</I></B>&#8221;), with an aggregate offering price of $37,919,578.05. The Registration Statement
incorporates by reference the Registration Statement on Form S-3 (Registration No. 333-264083) (the &#8220;<B><I>Prior Registration Statement</I></B>&#8221;),
which was declared effective on May 5, 2022, including the prospectus which forms part of the Registration Statement (the &#8220;<B><I>Prospectus</I></B>&#8221;)
and the supplements to the prospectus referred to therein (each a &#8220;<B><I>Prospectus Supplement</I></B>&#8221;).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The Securities are to be sold from time to time
as set forth in the Registration Statement, the Prospectus contained therein and the Prospectus Supplements. The Debt Securities are to
be issued pursuant to a debt securities indenture (the &#8220;<B><I>Indenture</I></B>&#8221;), a form of which has been filed as an exhibit
to the Prior Registration Statement and is to be entered into between the Company and a trustee to be named in a Prospectus Supplement
to the Registration Statement (the &#8220;<B><I>Trustee</I></B>&#8221;). The Securities are to be sold pursuant to a purchase, underwriting
or similar agreement in substantially the form to be filed under a Current Report on Form&nbsp;8-K. The Debt Securities are to be issued
in the form set forth in the Indenture. The Indenture may be supplemented in connection with the issuance of each such series of Debt
Securities, by a supplemental indenture or other appropriate action of the Company creating such series of Debt Securities.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">We have examined instruments, documents, certificates
and records that we have deemed relevant and necessary for the basis of our opinions hereinafter expressed. In such examination, we have
assumed: (a)&nbsp;the authenticity of original documents and the genuineness of all signatures; (b)&nbsp;the conformity to the originals
of all documents submitted to us as copies; (c)&nbsp;the truth, accuracy and completeness of the information, representations and warranties
contained in the instruments, documents, certificates and records we have reviewed; (d)&nbsp;that the Registration Statement, and any
amendments thereto (including post-effective amendments), will have become effective under the Act; (e)&nbsp;that a Prospectus Supplement
will have been filed with the Commission describing the Securities offered thereby; (f)&nbsp;that the Securities will be issued and sold
in compliance with applicable U.S. federal and state securities laws and in the manner stated in the Registration Statement and the applicable
Prospectus Supplement; (g)&nbsp;that a definitive purchase, underwriting or similar agreement with respect to any Securities offered
will have been duly authorized and validly executed and delivered by the Company and the other parties thereto; (h)&nbsp;that any Securities
issuable upon conversion, exchange, redemption or exercise of any Securities being offered will be duly authorized, created and, if appropriate,
reserved for issuance upon such conversion, exchange, redemption or exercise; (i)&nbsp;with respect to shares of Common Stock or Preferred
Stock, that there will be sufficient shares of Common Stock or Preferred Stock authorized under the Company&#8217;s organizational documents
that are not otherwise reserved for issuance; and (j)&nbsp;the legal capacity of all natural persons. As to any facts material to the
opinions expressed herein that were not independently established or verified, we have relied upon oral or written statements and representations
of officers and other representatives of the Company. The term &#8220;Board&#8221; means the Board of Directors of the Company or a duly
constituted and acting committee thereof.</P>

<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; text-transform: uppercase">austin&nbsp;&nbsp;&nbsp;beijing&nbsp;&nbsp;&nbsp;boston&nbsp;&nbsp;&nbsp;BOULDER&nbsp;&nbsp;&nbsp;brussels&nbsp;&nbsp;&nbsp;hong kong&nbsp;&nbsp;&nbsp;london&nbsp;&nbsp;&nbsp;los angeles&nbsp;&nbsp;&nbsp;new york&nbsp;&nbsp;&nbsp;palo alto<BR>
salt lake city&nbsp;&nbsp;&nbsp;san diego&nbsp;&nbsp;&nbsp;san francisco&nbsp;&nbsp;&nbsp;seattle&nbsp;&nbsp;&nbsp;shanghai&nbsp;&nbsp;&nbsp;washington, dc&nbsp;&nbsp;&nbsp;wilmington, de</FONT></P>

<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<!-- Field: Page; Sequence: 1 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><IMG SRC="tm243583d1_ex5-1img02.jpg" ALT="">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Edgewise Therapeutics, Inc.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">January 19, 2024</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Page </FONT>2</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">Based on such examination, we are of the opinion
that:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
<TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 56.35pt"></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 18pt">1.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">With respect to the shares of Common Stock, when: (a)&nbsp;the Board has taken all necessary corporate action to approve the issuance
and the terms of the offering of the shares of Common Stock and related matters; and (b)&nbsp;the shares of Common Stock have been duly
delivered either (i)&nbsp;in accordance with the applicable definitive purchase, underwriting or similar agreement approved by the Board,
or upon the exercise of Warrants to purchase Common Stock, upon payment of the consideration therefor (not less than the par value of
the Common Stock) provided for therein or (ii)&nbsp;upon conversion or exercise of any other Security, in accordance with the terms of
such Security or the instrument governing such Security providing for such conversion or exercise as approved by the Board, for the consideration
approved by the Board, then the shares of Common Stock will be validly issued, fully paid and nonassessable.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 74.35pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
<TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 56.35pt"></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 18pt">2.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">With respect to any particular series of shares of Preferred Stock, when: (a)&nbsp;the Board has taken all necessary corporate action
to approve the issuance and terms of the shares of Preferred Stock, the terms of the offering thereof, and related matters, including
the adoption of a certificate of designation (a &#8220;Certificate&#8221;) relating to such Preferred Stock conforming to the General
Corporation Law of the State of Delaware (the &#8220;<B><I>DGCL</I></B>&#8221;) and the filing of the Certificate with the Secretary of
State of the State of Delaware; and (b)&nbsp;the shares of Preferred Stock have been duly delivered either (i)&nbsp;in accordance with
the applicable definitive purchase, underwriting or similar agreement approved by the Board, or upon the exercise of Warrants to purchase
Preferred Stock, upon payment of the consideration therefor (not less than the par value of the Preferred Stock) provided for therein
or (ii)&nbsp;upon conversion or exercise of any other Security, in accordance with the terms of such Security or the instrument governing
such Security providing for such conversion or exercise as approved by the Board, for the consideration approved by the Board, then the
shares of Preferred Stock will be validly issued, fully paid and nonassessable.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 74.35pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
<TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 56.35pt"></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 18pt">3.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">With respect to Debt Securities to be issued under the Indenture, when: (<FONT STYLE="background-color: white">a)&nbsp;</FONT>the
Trustee is qualified to act as Trustee under the Indenture and the Company has filed a Form&nbsp;T-1 for the Trustee with the Commission;
(<FONT STYLE="background-color: white">b)&nbsp;</FONT>the Trustee has duly executed and delivered the Indenture; (<FONT STYLE="background-color: white">c)&nbsp;</FONT>the
Indenture has been duly authorized and validly executed and delivered by the Company to the Trustee; (<FONT STYLE="background-color: white">d)&nbsp;</FONT>the
Indenture has been duly qualified under the Trust Indenture Act of&nbsp;1939, as amended; (<FONT STYLE="background-color: white">e)&nbsp;</FONT>the
Board has taken all necessary corporate action to approve the issuance and terms of such Debt Securities, the terms of the offering thereof
and related matters; and (<FONT STYLE="background-color: white">f)&nbsp;</FONT>such Debt Securities have been duly executed, authenticated,
issued and delivered in accordance with the provisions of the Indenture and the applicable definitive purchase, underwriting or similar
agreement approved by the Board, or upon the exercise of Warrants to purchase Debt Securities, upon payment of the consideration therefor
provided for therein, such Debt Securities will constitute valid and binding obligations of the Company, enforceable against the Company
in accordance with their terms, and entitled to the benefits of the Indenture.</TD></TR></TABLE>




<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 74.35pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<!-- Field: Page; Sequence: 2 -->
    <DIV STYLE="border-bottom: Black 1pt solid; margin-top: 12pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><IMG SRC="tm243583d1_ex5-1img02.jpg" ALT="">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Edgewise Therapeutics, Inc.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">January 19, 2024</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Page </FONT>3</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
<TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 56.35pt"></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 18pt">4.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">With respect to Depositary Shares, when: (a)&nbsp;the Board has taken all necessary corporate action to approve the issuance and terms
of the Depositary Shares, the terms of the offering thereof, and related matters, including the adoption of a Certificate relating to
the Preferred Stock underlying such Depositary Shares and the filing of the Certificate with the Secretary of State of the State of Delaware;
(b)&nbsp;the Deposit Agreement (the &#8220;Deposit Agreement&#8221;) or agreements relating to the Depositary Shares and the related Depositary
Receipts (the &#8220;Depositary Receipts&#8221;) have been duly authorized and validly executed and delivered by the Company and the depositary
appointed by the Company; (c)&nbsp;the shares of Preferred Stock underlying such Depositary Shares have been deposited with a bank or
trust company (which meets the requirements for the depositary set forth in the Registration Statement) under the applicable Deposit Agreement;
and (d)&nbsp;the Depositary Receipts representing the Depositary Shares have been duly executed, countersigned, registered and delivered
in accordance with the appropriate Deposit Agreement and the applicable definitive purchase, underwriting or similar agreement approved
by the Board upon payment of the consideration therefor provided for therein, the Depositary Shares will be validly issued, fully paid
and nonassessable.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 74.35pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
<TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 56.35pt"></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 18pt">5.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">With respect to the Warrants, when: (a)&nbsp;the Board has taken all necessary corporate action to approve the issuance and terms
of the Warrants and related matters; and (b)&nbsp;the Warrants have been duly executed and delivered against payment therefor, pursuant
to the applicable definitive purchase, underwriting, warrant or similar agreement, as applicable, duly authorized, executed and delivered
by the Company and a warrant agent and the certificates for the Warrants have been duly executed and delivered by the Company and such
warrant agent, then the Warrants will constitute valid and binding obligations of the Company, enforceable against the Company in accordance
with their terms.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
<TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 56.35pt"></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 18pt">6.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">With respect to the Subscription Rights, when: (a)&nbsp;the Board has taken all necessary corporate action to authorize the issuance
and terms of the Subscription Rights, the terms of the offering thereof, and related matters and (b)&nbsp;the rights agreement under which
the Subscription Rights are to be issued has been duly authorized and validly executed and delivered by the Company, and upon payment
of the consideration for the Subscription Rights provided for in such rights agreement, if any, then the Subscription Rights will be valid
and binding obligations of the Company, enforceable against the Company in accordance with their terms.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
<TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 56.35pt"></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 18pt">7.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">With respect to the Purchase Contracts, when: (a)&nbsp;the Board has taken all necessary corporate action to approve the issuance
and terms of the Purchase Contracts and related matters and (b)&nbsp;the agreement under which the Purchase Contracts are to be issued
has been duly authorized and validly executed and delivered by the Company, then the Purchase Contracts will be valid and binding obligations
of the Company, enforceable against the Company in accordance with their terms.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
<TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 56.35pt"></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 18pt">8.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">With respect to the Units, when: (a)&nbsp;the Board has taken all necessary
                                                                                                                                                   corporate action to approve the issuance and terms of the Units (including any Securities underlying the Units) and related matters;
                                                                                                                                                   and (b)&nbsp;the Units (including any Securities underlying the Units) have been duly executed and delivered against payment
                                                                                                                                                   therefor, pursuant to the applicable definitive purchase, underwriting, or similar agreement duly authorized, executed and delivered
                                                                                                                                                   by the Company and any applicable unit or other agents, and the certificates for the Units (including any Securities underlying the
                                                                                                                                                   Units) have been duly executed and delivered by the Company and any applicable unit or other agents, then the Units will constitute valid
and binding obligations of the Company, enforceable against the Company in accordance with their terms.</TD></TR></TABLE>




<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 74.35pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<!-- Field: Page; Sequence: 3 -->
    <DIV STYLE="border-bottom: Black 1pt solid; margin-top: 12pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><IMG SRC="tm243583d1_ex5-1img02.jpg" ALT="">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Edgewise Therapeutics, Inc.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">January 19, 2024</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Page </FONT>4</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">Our opinion that any document is legal, valid and
binding is qualified as to:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
<TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 0.75in"></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 0.25in">a)</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">limitations imposed by bankruptcy, insolvency, reorganization, arrangement, fraudulent transfer, moratorium or other similar laws
relating to or affecting the rights of creditors generally;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 1in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
<TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 0.75in"></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 0.25in">b)</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">rights to indemnification and contribution, which may be limited by applicable law or equitable principles; and</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 1in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
<TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 0.75in"></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 0.25in">c)</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">the effect of general principles of equity, including without limitation concepts of materiality, reasonableness, good faith and fair
dealing, and the possible unavailability of specific performance or injunctive relief, whether considered in a proceeding in equity or
at law.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">We express no opinion herein as to the laws of
any state or jurisdiction other than the DGCL, the federal laws of the United States of America and the laws of the State of New York
as to the enforceability of the Debt Securities.&nbsp;&#9;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">We consent to the use of this opinion as an exhibit
to the Registration Statement, and we consent to the reference of our name wherever it appears in the Registration Statement, Prior Registration
Statement, Prospectus, any Prospectus Supplement, and in any amendment or supplement thereto. In giving this consent, we do not admit
that we are in the category of persons whose consent is required under Section 7 of the Securities Act or the rules and regulations of
the Commission thereunder.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 50%"><FONT STYLE="font-size: 10pt">Very truly yours,</FONT></TD>
    <TD STYLE="width: 50%"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font: 10pt Times New Roman, Times, Serif">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><FONT STYLE="font-size: 10pt">/s/ Wilson Sonsini Goodrich &amp; Rosati, P.C.</FONT></TD>
    <TD><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font: 10pt Times New Roman, Times, Serif">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><FONT STYLE="font-size: 10pt">WILSON SONSINI GOODRICH &amp; ROSATI</FONT></TD>
    <TD><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font: 10pt Times New Roman, Times, Serif; vertical-align: top">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><FONT STYLE="font-size: 10pt">Professional Corporation</FONT></TD>
    <TD><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<!-- Field: Page; Sequence: 4; Options: Last -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>



<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"></P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>tm243583d1_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0pt">&nbsp;</P>

<P STYLE="text-align: right; margin: 0pt"><B>Exhibit 23.1</B></P>

<P STYLE="margin: 0pt; text-align: right">&nbsp;</P>

<P STYLE="margin: 0pt; text-align: right"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 25%; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><IMG SRC="tm243583d1_ex23-1img001.jpg" ALT=""></FONT></TD>
    <TD STYLE="width: 75%; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 10pt">KPMG LLP<BR>
 Suite&nbsp;800<BR> 1225 17th Street<BR> Denver, CO 80202-5598</TD>
    <TD></TD></TR>
  </TABLE>
<P STYLE="margin: 0pt; text-align: right">&nbsp;&nbsp;</P>

<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><B>Consent of Independent
Registered Public Accounting Firm</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">We consent to the incorporation by reference in the registration statement
(No.&nbsp;333-264083) on Form&nbsp;S-3 of our report dated February&nbsp;23,&nbsp;2023, with respect to the financial statements of Edgewise
Therapeutics,&nbsp;Inc.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">/s/ KPMG LLP</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Denver, Colorado<BR>
January&nbsp;19,&nbsp;2024</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" BORDER="0" STYLE="width: 100%; margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">
<TR STYLE="vertical-align: top">
  <TD STYLE="width: 20%">&nbsp;</TD>
  <TD STYLE="width: 80%">KPMG LLP, a Delaware limited liability partnership and a member firm of <BR>
the KPMG global organization of independent member firms affiliated with <BR>
KPMG International Limited, a private English company limited by guarantee.</TD></TR>
</TABLE>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 1; Options: Last -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="margin: 0pt">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>4
<FILENAME>tm243583d1_ex-filingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"><B>Exhibit&nbsp;107.1</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>CALCULATION OF FILING FEE TABLES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>FORM&nbsp;S-3</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Form&nbsp;Type)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>EDGEWISE THERAPEUTICS,&nbsp;INC.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Exact Name of Registrant as Specified in its Charter)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><U>Table 1: Newly Registered Securities</U></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="border-top: black 1pt solid; white-space: nowrap; border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-top: black 1pt solid; border-left: Black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap">&nbsp;</TD>
    <TD STYLE="border-left: Black 1pt solid; padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Security</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Type</B></P></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt"><B>Title of each<BR>
 Class of <BR>
Securities to<BR>
 be Registered</B></FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Fee</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Calculation</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Rule</B></P></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Amount to</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>be</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Registered</B></P></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Proposed</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Maximum</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Offering</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Price Per</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Share</B></P></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Proposed</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Maximum</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Aggregate</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Offering</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Price</B></P></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Fee</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Rate</B></P></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Amount of</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Registration</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Fee</B></P></TD></TR>
  <TR>
    <TD STYLE="border-top: black 1pt solid; white-space: nowrap; border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-top: black 1pt solid; border-left: Black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap; padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Fees to be</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Paid</P></TD>
    <TD STYLE="border-left: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Equity</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Common stock, par value</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">$0.0001 per share</P></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">457(o)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap; padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Fees to be</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Paid</P></TD>
    <TD STYLE="border-left: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Equity</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Preferred Stock, par value $0.0001 per share</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">457(o)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap; padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Fees to be</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Paid</P></TD>
    <TD STYLE="border-left: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Debt</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Debt Securities</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">457(o)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap; padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Fees to be</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Paid</P></TD>
    <TD STYLE="border-left: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Equity</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Depositary Shares</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">457(o)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap; padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Fees to be</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Paid</P></TD>
    <TD STYLE="border-left: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Other</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Warrants</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">457(o)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap; padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Fees to be</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Paid</P></TD>
    <TD STYLE="border-left: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Other</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Subscription Rights</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">457(o)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap; padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Fees to be</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Paid</P></TD>
    <TD STYLE="border-left: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Other</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Purchase Contracts</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">457(o)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap; padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Fees to be</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Paid</P></TD>
    <TD STYLE="border-left: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Other</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Units</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">457(o)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&minus;</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-bottom: Black 1pt solid; border-left: black 1pt solid; white-space: nowrap; padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Fees to be</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Paid</P></TD>
    <TD STYLE="border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Unallocated (Universal Shelf)</FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">Unallocated (Universal Shelf)</FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">457(o)</FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">$37,919,578.05 (1)</P></TD>
    <TD STYLE="border-bottom: Black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">0.0001476</FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">$5,596.93</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap; padding-bottom: 1pt"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="border-left: Black 1pt solid; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="padding-bottom: 1pt"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD></TR>
  <TR>
    <TD STYLE="border-top: black 1pt solid; white-space: nowrap; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-top: black 1pt solid; border-left: Black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-left: Black 1pt solid; padding-bottom: 1pt"><FONT STYLE="font-size: 10pt">&thinsp;Total Offering Amounts&thinsp;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">$37,919,578.05 (1)</P></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">$5,596.93</FONT></TD></TR>
  <TR>
    <TD STYLE="border-top: black 1pt solid; white-space: nowrap; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-top: black 1pt solid; border-left: Black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-left: Black 1pt solid; padding-bottom: 1pt"><FONT STYLE="font-size: 10pt">&thinsp;Total Fees Previously Paid&thinsp;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&mdash;</FONT></TD></TR>
  <TR>
    <TD STYLE="border-top: black 1pt solid; white-space: nowrap; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-top: black 1pt solid; border-left: Black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-left: black 1pt solid; white-space: nowrap">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-left: Black 1pt solid; padding-bottom: 1pt"><FONT STYLE="font-size: 10pt">&thinsp;Total Fee Offsets&thinsp;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="border-left: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">&mdash;</FONT></TD></TR>
  <TR>
    <TD STYLE="border-top: black 1pt solid; white-space: nowrap; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-top: black 1pt solid; border-left: Black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-left: black 1pt solid">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-bottom: black 1pt solid; white-space: nowrap; border-left: black 1pt solid">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-left: Black 1pt solid; border-bottom: black 1pt solid; padding-bottom: 1pt"><FONT STYLE="font-size: 10pt">&thinsp;Net Fee Due&thinsp;</FONT></TD>
    <TD STYLE="border-left: black 1pt solid; border-bottom: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-bottom: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-left: black 1pt solid; border-bottom: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-bottom: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-left: black 1pt solid; border-bottom: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-bottom: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-left: black 1pt solid; border-bottom: black 1pt solid">&nbsp;</TD>
    <TD STYLE="border-bottom: black 1pt solid; border-right: black 1pt solid; padding-right: 2.4pt; padding-bottom: 1pt; text-align: center"><FONT STYLE="font-size: 10pt">$5,596.93</FONT></TD></TR>
  </TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The registrant previously registered the offer and sale of certain securities having a proposed maximum aggregate offering price of $400,000,000 pursuant to a Registration Statement on Form S-3 (File No. 333-</FONT><FONT STYLE="font-size: 10pt">264083) (the &ldquo;Prior Registration Statement&rdquo;), which was initially filed on April 1, 2022 and declared effective by the Securities and Exchange Commission on May 5, 2022. As of the date hereof, a balance of $202,080,423.95 of such securities remains unsold under the Prior Registration Statement. In accordance with Rule 462(b) under the Securities Act of 1933, as amended, and General Instruction IV(A) of Form S-3, the registrant is hereby registering the offer and sale of an additional $37,919,578.05 of its Securities. The additional amount of Securities that is being registered for offer and sale represents no more than 20% of the maximum aggregate offering price of the remaining securities available to be sold under the Prior Registration Statement. </FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 1; Options: Last -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>tm243583d1_ex23-1img001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
begin 644 tm243583d1_ex23-1img001.jpg
M_]C_X  02D9)1@ ! 0$ R #(  #_VP!#  $! 0$! 0$! 0$! 0$! 0$! 0$!
M 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0'_
MVP!# 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$!
M 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0'_P  1"  V ' # 2(  A$! Q$!_\0
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MVEM?HOQ/F3_A9W[1?_1KQ_\ #U>"?_C57O@A\<=0^+NH_&K0-9\!:CX"\6?
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M-0M/$=]HKW>ES>+[/P9X*U&RDU-/*\*W-I:QO%#''L_9+_@B]^S!\??VC_\
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;H4444 %%%% !1110 4444 %%%% !1110!__9

end
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>tm243583d1_ex5-1img01.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
begin 644 tm243583d1_ex5-1img01.jpg
M_]C_X  02D9)1@ ! 0$ 8 !@  #_VP!#  @&!@<&!0@'!P<)"0@*#!0-# L+
M#!D2$P\4'1H?'AT:'!P@)"XG("(L(QP<*#<I+# Q-#0T'R<Y/3@R/"XS-#+_
MVP!# 0@)"0P+#!@-#1@R(1PA,C(R,C(R,C(R,C(R,C(R,C(R,C(R,C(R,C(R
M,C(R,C(R,C(R,C(R,C(R,C(R,C(R,C+_P  1" !% )X# 2(  A$! Q$!_\0
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1T8HHH 3&:,444 +1110!_]D!

end
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>tm243583d1_ex5-1img02.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
begin 644 tm243583d1_ex5-1img02.jpg
M_]C_X  02D9)1@ ! 0$ 8 !@  #_VP!#  @&!@<&!0@'!P<)"0@*#!0-# L+
M#!D2$P\4'1H?'AT:'!P@)"XG("(L(QP<*#<I+# Q-#0T'R<Y/3@R/"XS-#+_
MVP!# 0@)"0P+#!@-#1@R(1PA,C(R,C(R,C(R,C(R,C(R,C(R,C(R,C(R,C(R
M,C(R,C(R,C(R,C(R,C(R,C(R,C(R,C+_P  1"  G %,# 2(  A$! Q$!_\0
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96V68>6Z]#P><8[YHHHNQ\J[&C1112&?_V0$!

end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
