Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We consent to the incorporation by reference in Registration Statement Nos. 333-117811, 333-127876,
333-137332, and 333-149049 on Form S-8 of our report dated February 27, 2009, relating to the
financial statements of MannKind Corporation and of our report dated February 27, 2009 relating to
the effectiveness of MannKind Corporation’s internal control over financial reporting, appearing in
the Annual Report on Form 10-K of MannKind Corporation for the year ended December 31, 2008.
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Deloitte & Touche LLP |
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Los Angeles, California |
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February 27, 2009
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