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Income Taxes - Additional Information (Detail) (USD $) | 1 Months Ended | 12 Months Ended
--- | --- | ---
Aug. 31, 2004 | Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2010
Income Taxes [Line Items] |  |  |  |
Deferred tax assets |  | $ 784,600,000 | $ 718,200,000 |
Deferred tax liabilities |  | 34,400,000 | 28,800,000 |
Change in the valuation allowance |  | 60,700,000 | 57,200,000 | 56,500,000
Federal operating loss carryforwards |  | 1,600,000,000 |  |
State operating loss carryforwards |  | 1,100,000,000 |  |
Net operating loss carryforwards | 216,000,000 |  |  |
Net operating loss and credit carryforwards, annual use limitation | 13,000,000 |  |  |
Research and development credits subject to expiration |  | $ 77,400,000 |  |
Research and development credits, expiration year |  | 2033 |  |
Minimum |  |  |  |
Income Taxes [Line Items] |  |  |  |
Net operating loss carry-forwards, expiration year |  | 2013 |  |
Maximum |  |  |  |
Income Taxes [Line Items] |  |  |  |
Net operating loss carry-forwards, expiration year |  | 2014 |  |

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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards expected to be realized or consumed within one year or operating cycle, if longer. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Deferred Tax Asset -URI http://asc.fasb.org/extlink&oid=6510090 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 109 -Paragraph 41, 42, 43, 289 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 45 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=21917399&loc=d3e31917-109318 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 45 -Paragraph 7 -URI http://asc.fasb.org/extlink&oid=21917399&loc=d3e31938-109318 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 45 -Paragraph 6 -URI http://asc.fasb.org/extlink&oid=21917399&loc=d3e31931-109318 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32537-109319 + Details
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