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Condensed Consolidated Statements Of Operations (USD $)
In Thousands, except Per Share data, unless otherwise specified
 3 Months Ended 6 Months Ended 268 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Revenue         $ 3,166
Operating expenses:          
Research and development 27,052 26,638 53,450 50,794 1,521,023
General and administrative 14,533 17,416 24,572 27,193 450,276
In-process research and development costs         19,726
Goodwill impairment         151,428
Total operating expenses 41,585 44,054 78,022 77,987 2,142,453
Loss from operations (41,585) (44,054) (78,022) (77,987) (2,139,287)
Other income (expense) 15 13,347 38 14,729 (2,229)
Interest expense on note payable to related party (1,689) (3,028) (3,378) (6,076) (42,203)
Interest expense on senior convertible notes (2,866) (2,844) (5,729) (5,419) (45,662)
Interest income 1 1 2 2 36,998
Loss before benefit for income taxes (46,124) (36,578) (87,089) (74,751) (2,192,383)
Income tax benefit         382
Net loss (46,124) (36,578) (87,089) (74,751) (2,192,001)
Deemed dividend related to beneficial conversion feature of convertible preferred stock         (22,260)
Accretion on redeemable preferred stock         (952)
Net loss applicable to common stockholders $ (46,124) $ (36,578) $ (87,089) $ (74,751) $ (2,215,213)
Net loss per share applicable to common stockholders - basic and diluted $ (0.16) $ (0.23) $ (0.31) $ (0.49)  
Shares used to compute basic and diluted net loss per share applicable to common stockholders 284,044 159,859 282,062 151,506