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Accrued Expenses and Other Current Liabilities (Detail) (USD $)
In Thousands, unless otherwise specified
Sep. 30, 2013
Dec. 31, 2012
Accrued Expenses and Other Current Liabilities [Line Items]    
Salary and related expenses $ 9,414 $ 10,074
Research and clinical study costs 3,155 5,995
Accrued interest 3,265 4,533
Construction in progress 226 3,878
Other 5,493 1,297
Accrued expenses and other current liabilities $ 21,553 $ 25,777