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Facility Financing Agreement - Additional Information (Detail) (USD $) Share data in Millions, except Per Share data, unless otherwise specified	9 Months Ended	272 Months Ended				1 Months Ended						1 Months Ended		1 Months Ended			1 Months Ended
	Sep. 30, 2013	Sep. 30, 2013	Jul. 01, 2013 Registration Rights Agreement	Jul. 01, 2013 Facility Agreement Maximum	Sep. 30, 2013 Senior convertible notes due December 31 2019	Jul. 01, 2013 Senior convertible notes due December 31 2019 Tranche One	Jul. 01, 2013 Senior convertible notes due December 31 2019 Milestone Rights	Jul. 01, 2013 Deerfield	Jul. 01, 2013 Deerfield Tranches Three and Four	Sep. 30, 2013 Deerfield Maximum Milestone Rights	Jul. 01, 2013 Deerfield Maximum Milestone Rights	Jul. 01, 2013 Deerfield Senior convertible notes due December 31 2019	Sep. 30, 2013 Deerfield Senior convertible notes due December 31 2019	Jul. 01, 2013 Deerfield Senior convertible notes due December 31 2019 Tranche One	Jul. 01, 2013 Deerfield Senior convertible notes due December 31 2019 Milestone Rights	Jul. 01, 2013 Deerfield Senior convertible notes due December 31 2019 Tranche Two	Jul. 01, 2013 Deerfield Senior convertible notes due December 31 2019 Maximum	Jul. 01, 2013 Deerfield Senior convertible notes due December 31 2019 Minimum
Debt Instrument [Line Items]
Debt facility principal amount					$ 80,000,000							$ 160,000,000		$ 40,000,000		$ 40,000,000
Debt facility periodic principal amount												40,000,000
Interest rate												9.75%
Debt facility maturity year												2019
Shares issued upon conversion																	12.0
Debt facility conversion price																		$ 3.33
Repayment as a percentage of original principal amount												25.00%		110.00%
Debt instrument maturity date												Dec. 31, 2019
Minimum available amount of credit facility under covenant restrictions				25,000,000
Value received, from Tranche 1 Notes and Milestone Rights												52,900,000
Proceeds from debt issuance														39,500,000
Commitment asset at fair value												13,400,000
Estimated fair values debt issued					75,700,000									37,100,000	16,300,000
Effective interest rate														12.19%		12.45%
Debt discount														3,300,000		3,700,000
Payment for debt issue costs	598,000	598,000						500,000				448,737
Debt issuance costs								597,529	259,800			536,266
Contingent liability for milestone payments										90,000,000	90,000,000
Short term liability															3,200,000
Long term liability	$ 72,933,000	$ 72,933,000			$ 72,933,000										$ 13,100,000
Discount rate						12.00%	17.50%								17.50%
Risk premium															5.00%
Share registration statement shares of common stock to be registered			12.0
Additional damage calculation percentage													1.00%

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